Hua LiState College, PA
Hua Li Phones & Addresses
State College, PA
Newark, DE
Arlington, VA
Washington, DC
Mentions for Hua Li
Publications & IP owners
Us Patents
Dna Encoding Peripheral-Type Benzodiazipine Receptor Associated Protein 7 And Applications Or Methods Of Use
US Patent:
7056694, Jun 6, 2006
Filed:
Aug 11, 1999
Appl. No.:
09/762594
Inventors:
Vassilios Papadopoulos - North Potomac MD, US
Hua Li - North Potomac MD, US
Hua Li - North Potomac MD, US
Assignee:
Georgetown University - Washington DC
International Classification:
C07H 21/04
C12N 1/20
C12N 15/09
C12N 5/00
C12P 21/00
C12N 1/20
C12N 15/09
C12N 5/00
C12P 21/00
US Classification:
435 691, 435 701, 4352523, 4353201, 435325, 435 711, 536 231, 536 235, 530350
Abstract:
The present invention relates to nucleic acids encoding peripheral-type benzodiazepine receptor (PBR)-associated proteins (PAPs), and nucleic acids that hybridize or are variant of nucleic acids encoding the peripheral-type benzodiazepine receptor (PBR)-associated proteins (PAPs), which are capable of encoding proteins that regulate the function of PBRs affecting both steroid biosynthesis and mediating cholesterol delivery as well as other PBR-mediated functions.
Cd16A Binding Proteins And Use For The Treatment Of Immune Disorders
US Patent:
7351803, Apr 1, 2008
Filed:
May 29, 2003
Appl. No.:
10/449566
Inventors:
Leslie S. Johnson - Darnestown MD, US
Ling Huang - Gaithersburg MD, US
Hua Li - North Potomac MD, US
Nadine Tuaillon - Sykesville MD, US
Ling Huang - Gaithersburg MD, US
Hua Li - North Potomac MD, US
Nadine Tuaillon - Sykesville MD, US
Assignee:
Macrogenics, Inc. - Rockville MD
International Classification:
C07K 16/00
C12P 21/08
C07K 17/00
C12P 21/08
C07K 17/00
US Classification:
5303871, 5303873, 5303881, 53038822
Abstract:
CD16A binding proteins useful for the reduction of a deleterious immune response are described. In one aspect, humanized anti-CD16A antibodies, optionally lacking effector function, are used for treatment of immune disorders such as idiopathic thrombocytopenic purpura and autoimmune hemolytic anemia.
Cd16A Binding Proteins And Use For The Treatment Of Immune Disorders
US Patent:
7618628, Nov 17, 2009
Filed:
Jun 4, 2007
Appl. No.:
11/757932
Inventors:
Leslie S. Johnson - Darnestown MD, US
Ling Huang - Bethesda MD, US
Hua Li - North Potomac MD, US
Nadine Tuaillon - Sykesville MD, US
Ling Huang - Bethesda MD, US
Hua Li - North Potomac MD, US
Nadine Tuaillon - Sykesville MD, US
Assignee:
Macrogenics Inc. - Rockville MD
International Classification:
A61K 39/395
C07K 16/00
C07K 16/00
US Classification:
4241301, 5303871
Abstract:
CD16A binding proteins useful for the reduction of a deleterious immune response asre described. In one aspect, humanized anti-cd16A antibodies, optionally lacking effector function, are used for the treatment of immune disorders such as idiopathic thrombocytopenic purpura and autoimme hemolytic anemia.
Fcγriib Fusion Proteins And Compositions Thereof
US Patent:
7700100, Apr 20, 2010
Filed:
Jan 13, 2004
Appl. No.:
10/756153
Inventors:
Leslie S. Johnson - Darnstown MD, US
Hua Li - Gaithersburg MD, US
Nadine Tuaillon - Gettysburg PA, US
Hua Li - Gaithersburg MD, US
Nadine Tuaillon - Gettysburg PA, US
Assignee:
Macrogenics, Inc. - Rockville MD
International Classification:
A61K 39/395
US Classification:
4241341, 4241441, 4241851, 4241921
Abstract:
The present invention relates to molecules, preferably soluble (i. e. , not membrane bound) polypeptides, most preferably soluble fusion polypeptides comprising the extracellular soluble regions of FcγRIIB, derivatives and analogs thereof, and nucleic acids encoding same. Molecules of the invention are particularly useful for the treatment, management, or prevention of, or amelioration of one or more symptoms of, an autoimmune disease, especially for ameliorating serum platelet deficiency associated with immune thrombocytopenic purpura. The invention provides methods and compositions for enhancing the therapeutic efficacy of standard, current or experimental therapies for an autoimmune disease by administering a molecule of the invention.
Cd16A Binding Proteins And Use For The Treatment Of Immune Disorders
US Patent:
7838635, Nov 23, 2010
Filed:
Jun 4, 2007
Appl. No.:
11/757939
Inventors:
Leslie S. Johnson - Darnestown MD, US
Ling Huang - Bethesda MD, US
Hua Li - North Potomac MD, US
Nadine Tuaillon - Sykesville MD, US
Ling Huang - Bethesda MD, US
Hua Li - North Potomac MD, US
Nadine Tuaillon - Sykesville MD, US
Assignee:
MacroGenics, Inc. - Rockville MD
International Classification:
C07K 16/00
C12P 21/08
C07K 14/00
C12N 15/00
C12P 21/08
C07K 14/00
C12N 15/00
US Classification:
5303871, 5303873, 5303881, 53038822
Abstract:
CD16A binding proteins useful for the reduction of a deleterious immune response are described. In one aspect, humanized anti-cd16A antibodies, optionally lacking effector function, are used for the treatment of immune disorders such as idiopathic thrombocytopenic purpura and autoimmune hemolytic anemia.
Peripheral-Type Benzodiazepine Receptor Associated Proteins, Cloning, Expression And Methods Of Use
US Patent:
2006010, May 18, 2006
Filed:
Jan 13, 2006
Appl. No.:
11/331940
Inventors:
Vassilios Papadopoulos - North Potomac MD, US
Hua Li - North Potomac MD, US
Hua Li - North Potomac MD, US
International Classification:
C07K 14/705
C07K 16/28
C12Q 1/68
G01N 33/53
C07H 21/04
C12P 21/06
A61K 39/395
C07K 16/28
C12Q 1/68
G01N 33/53
C07H 21/04
C12P 21/06
A61K 39/395
US Classification:
530350000, 435069100, 435320100, 435325000, 435007100, 530388220, 435006000, 424143100, 536023500
Abstract:
The present invention relates to nucleic acids encoding PBR-associated proteins (PAPs) and methods for use in producing PAPs and methods of using PAPs. In this study we have identified proteins (PAPs) that interact with PBR protein by a yeast two-hybrid system. We used PBR as bait to screen a mouse testis cDNA library. Five clones were isolated based on their ability to interact with PBR. These proteins may be involved in the regulation of the function of PBR, serving as an endogenous ligand or allosteric modulator of the receptor.
Fcgammariib Fusion Proteins And Compositions Thereof
US Patent:
2010019, Aug 5, 2010
Filed:
Mar 11, 2010
Appl. No.:
12/721887
Inventors:
Leslie S. Johnson - Darnestown MD, US
Hua Li - Gaithersburg MD, US
Nadine Tuaillon - Gettysburg PA, US
Hua Li - Gaithersburg MD, US
Nadine Tuaillon - Gettysburg PA, US
Assignee:
MacroGenics, Inc. - Rockville MD
International Classification:
A61K 39/395
A61P 37/00
A61P 37/00
US Classification:
4241341
Abstract:
The present invention relates to molecules, preferably soluble (i.e., not membrane bound) polypeptides, most preferably soluble fusion polypeptides comprising the extracellular soluble regions of an FcγR, derivatives and analogs thereof, and nucleic acids encoding same. Molecules of the invention are particularly useful for the treatment, management, or prevention of, or amelioration of one or more symptoms of, an autoimmune disease, especially for ameliorating serum platelet deficiency associated with immune thrombocytopenic purpura. The invention provides methods and compositions for enhancing the therapeutic efficacy of standard, current or experimental therapies for an autoimmune disease by administering a molecule of the invention.
Cd16A Binding Proteins And Use For The Treatment Of Immune Disorders
US Patent:
2011015, Jun 23, 2011
Filed:
Oct 14, 2010
Appl. No.:
12/904554
Inventors:
Leslie S. Johnson - Darnestown MD, US
Ling Huang - Gaithersburg MD, US
Hua Li - North Potomac MD, US
Nadine Tuaillon - Sykesville MD, US
Ling Huang - Gaithersburg MD, US
Hua Li - North Potomac MD, US
Nadine Tuaillon - Sykesville MD, US
Assignee:
MacroGenics, Inc. - Rockville MD
International Classification:
C07K 16/28
US Classification:
5303873
Abstract:
CD 16A binding proteins useful for the reduction of a deleterious immune response asre described. In one aspect, humanized anti-cd16A antibodies, optionally lacking effector function, are used for the treatment of immune disorders such as idiopathic thrombocytopenic purpura and autoimme hemolytic anemia.
Isbn (Books And Publications)
Rotating Shell Dynamics
Author:
Hua Li
ISBN #:
0080444776
Vision Chips: Implementing Vision Algorithms With Analog Vlsi Circuits
Author:
Hua Li
ISBN #:
0818664916
Vision Chips: Implementing Vision Algorithms With Analog Vlsi Circuits
Author:
Hua Li
ISBN #:
0818664924
Fuzzy Logic And Intelligent Systems
Author:
Hua Li
ISBN #:
0792395751
Chan Ye Jie Gou You Hua Yu Guo You Jing Ji Zhan Lue Xing Tiao Zheng: Mo Xing Fen Xi Ji Zheng Ce Yan Jiu =Chanyejiegouyouhuayugouyoujingjizhanluexingtiaozheng
Author:
Hua Li
ISBN #:
7501719748
Video Data Compression For Multimedia Computing: Statistically Based And Biologically Inspired Techniques
Author:
Hua Harry Li
ISBN #:
0792397908
Possible Relatives
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