Huan Xu resumes & CV records
Resumes
Huan Xu
Huan XuRaleigh, NC
Huan Xu Phones & Addresses
Raleigh, NC
Chapel Hill, NC
Mentions for Huan Xu
Publications & IP owners
Us Patents
Nano-Puerarin Regulates Tumor Microenvironment And Facilitates Chemo- And Immunotherapy In Murine Triple Negative Breast Cancer Model
US Patent:
2022019, Jun 23, 2022
Filed:
Apr 23, 2020
Appl. No.:
17/605377
Inventors:
- Chapel Hill NC, US
Huan Xu - Chapel Hill NC, US
Huan Xu - Chapel Hill NC, US
International Classification:
A61K 31/7048
A61K 9/107
A61K 47/24
A61K 47/18
A61K 31/337
A61K 39/395
A61P 35/00
A61K 9/107
A61K 47/24
A61K 47/18
A61K 31/337
A61K 39/395
A61P 35/00
Abstract:
Disclosed are nanoemulsions comprising puerarin and methods of their use in treating cancer, including breast cancer and melanoma. The presently disclosed puerarin-containing nanoemulsions regulate the tumor microenvironment and importantly de-activate tumor associated fibroblasts (TAFs) rather than killing them. The presently disclosed methods can be used in combination with chemotherapy, e.g., polymer formulations of paclitaxel, or PD-L1 blockade therapy to treat cancer.
Possible Relatives
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