Jack Bin Zhang, 40Whittier, CA

6357626, Mar 19, 2002

Mar 5, 2001

09/798049

Jack Yongfeng Zhang - Rancho Cucamonga CA, 91730
Anthony D. Marrs - Rancho Cucamonga CA, 91730
Mary Ziping Luo - Rancho Cucamonga CA, 91730

A61J 700

222 78, 222212, 222215, 222420, 2225411

A pre-filled oral liquid disposable plastic container along with its storage means are provided to deliver medication to a patient in a easy to use and sanitary manner. The plastic container ( ) includes a hollow bulb portion ( ) on one end and a hollow stem portion ( ) on the other. A bulbous flange ( ) is integrally formed onto the distal end or the hollow stem, thus permitting comfortable insertion of the container into a patients mouth. A specified quantity of liquid medication ( ) is pre-filled into the container with the container sized appropriately. The plastic in the container is colored, thereby indicating the type of liquid medication, and permitting the medication to be colorless and still maintain its identity. All of the containers have a recognizable shape on the bulb portion, such as a cylinder with spherical ends for adult medicine, or in some shape attractive to infants and small children. A metallic foil closure ( ) is attached to the distal end of the container for sealing the liquid medication within, and a tab ( ) is included for ease of removal.

6399087, Jun 4, 2002

Dec 20, 2000

09/745018

Jack Yongfeng Zhang - Rancho Cucamonga CA
Jie Fei Ding - Rancho Cucamonga CA
Mary Zi-ping Luo - Rancho Cucamonga CA

Amphastar Pharmaceuticals, Inc. - Rancho Cucamonga CA

A01N 2500

424405, 424757, 514731, 514816, 514938

A sterile, stable pharmaceutical formulations of oil-in-water emulsions of Propofol containing no preservative are provided that comprise optimal amounts of egg lecithin and soybean oil, with a suitable pH range to prevent significant growth of microorganisms for at least 24 hours after adventitious, extrinsic contamination. The lower pH in the formulation has shown the most antimicrobial activity. The reduced amount of fat in the formulation also allows chronic sedation over extended periods of time with a reduced chance of fat overload in the blood.

6418982, Jul 16, 2002

Nov 21, 2000

09/718111

Jack Y. Zhang - South El Monte CA
Mary Ziping Luo - South El Monte CA
Frank Z Xia - South El Monte CA

Amphastar Pharmaceuticals Inc. - Rancho Cucamonga CA

B65B 104

141 4, 141 65, 141 37, 141 2, 141 18, 141234

A process of bulk filling containers which includes the steps of arranging a number of containers upside down in a tray ( ) that has a raised peripheral lip ( ). This tray full of containers is then placed in a vacuum chamber ( ) which is then evacuated to a predetermined level below atmospheric pressure. Liquid ( ) is then introduced into the tray through a reservoir ( ) and conduit ( ) which penetrates the wall of the vacuum chamber and the vacuum within the chamber is gradually released at a rate that draws the liquid into the containers. At this point in the process unwanted liquid is rinsed away and the tray is removed from the chamber and turned right side up. The final step is to seal the top of the containers with an appropriate cap, barrier, tip or connection. A second embodiment adds a step to the process by positioning the containers upside down in a rack ( ) and positioning the rack directly above the tray containing the liquid. The rack is then lowered until the container necks are immersed in the liquid.

6425403, Jul 30, 2002

May 11, 2000

09/569013

Richard Chun Lin Lu - Chino CA
Charles Can Lin Wu - Chino CA
Mary Luo - Chino CA
Jack Zhang - Chino CA

Naturastar, Inc. - Chino CA

A61K 713

132208, 132206, 132211, 132270

A hair dyeing process which utilizes a hair dye in combination with a heat application means. By applying heat to a persons head, immediately after the dye has been applied, the hair can be quickly and efficiently dyed and hair damage is minimized. The heat application means ( ) is disclosed in five designs: the first utilizes a conventional, hand-held, hot-air blower ( ) in combination with a plastic head cap ( ) such as a shower cap ( ); the second utilizes the plastic head cap ( ) having attached a light flexible hose ( ) that is connected to a heat source ( ); the third consists of a hot, moistened towel ( ); the fourth consists of a corded, electric heating pad ( ); the fifth consists of a cordless heating pad ( ) that has inserted a multiplicity of heat absorbing elements ( ). When the pad ( ) is heated in a microwave oven the elements ( ) allow the pad ( ) to retain heat for an extended period of time.

6457612, Oct 1, 2002

Oct 12, 2001

09/975126

Jack Yongfeng Zhang - South El Monte CA
Mary Zi-Ping Luo - South El Monte CA
Frank Zhishi Xia - South El Monte CA

Amphastar Pharmaceuticals Inc. - Rancho Cucamonga CA

A47G 1914

2224651, 222107, 422100, 422 99, 7386332, 7386401, 7386453

An improved pre-filled disposable pipette ( ) consisting of a hollow tube ( ) dimensioned to enclose a medicinal product and having attached a medication transfer tube ( ) from where the pipette is filled and the medicinal product released. The improvement consists in having a primary grasping tab ( ) attached to an upper end ( ) of the bulb ( ); a secondary grasping tab ( ) attached to each side of the tube ( ); and a support tab ( ) also attached to each side of the tube ( ) near the lower end ( ) of the tube ( ). The primary and secondary grasping tabs ( ) allow the pipette ( ) to be conveniently and easily handled without having to grasp the sensitive bulb ( ) or to directly grasp the tube ( ). The support tab ( ) functions to allow the pipette ( ) to be placed on a conveyor rack apparatus ( ) from where the pipette ( ) can be automatically filled and sealed by a cap ( ) or heat applied foil ( ).

6551298, Apr 22, 2003

Nov 21, 2000

09/718112

Jack Y. Zhang - South El Monte CA, 91733
Frank Zhishi Xia - So. El Monte CA, 91733
Mary Ziping Luo - So. El Monte CA, 91733

A61B 1900

604403, 206363, 604 91, 604259, 604162

A controlled medicament security enclosure system that houses liquid filled reservoirs which consists of a portable enclosure ( ) formed with a top half ( ) and a bottom half ( ) that permanently snap together to form a secure inseparable repository for the reservoirs. Inside the enclosure is at least one glass vial ( ) for storing the liquid medicament with each vial having a sliding piston stopper ( ) within that seals the inside of the vial and slides to maintain the liquid air free regardless of the volume. An adapter socket ( ) is removably attached to the stopper and includes a hollow needle that pierces the stopper and permits a flowpath for the liquid. A flexible outlet tube ( ) along with connectors on each end transmit the medicament to a mechanical drug delivery system that has a peristaltic pump and a control module.

6793076, Sep 21, 2004

Mar 5, 2002

10/090033

Mary Ziping Luo - South El Monte CA
Jack Yongfeng Zhang - South El Monte CA
Frank Z. Xia - South El Monte CA
Rong Zhou - South El Monte CA
Denny R. S. Ko - South El Monte CA

Amphastar Pharmaceuticals, Inc. - Rancho Cucamonga CA

B65D 8102

206521, 206592, 215 121

A glass bottle protective enclosure ( ) designed to protect a glass bottle ( ) in the event the bottle is subjected to an impact shock. The enclosure is provided with a leak-proof seal and is particularly adapted for protecting glass bottles ( ) containing toxic injectable medication. The enclosure ( ), which is preferably made from a transparent plastic, consists of a lower bottle container ( ) which includes a base ( ) and a plurality of shock absorbing protrusions ( ), which are located to allow a bottle label to be clearly visible, on the base ( ) is located at least one sensor cavity ( ) into which is inserted an enclosure leakage sensor ( ) consisting of either a water soluble sensor ( ) or an electronic sensor ( ). Both of which provide an indication if a bottle leakage occurs. To complete the enclosure ( ) the container ( ) includes a threaded bottle container cap ( ) which includes a plurality of cap shock absorbing protrusions ( ).

6827479, Dec 7, 2004

Sep 30, 2002

10/261552

Frank Zhishi Xia - South El Monte CA
Mary Ziping Luo - South El Monte CA
Jack Yongfeng Zhang - South El Monte CA

Amphastar Pharmaceuticals Inc. - Rancho Cucamonga CA

B01F 504

3661624, 3661732, 3661764, 3661818, 3661822

A uniform small particle homogenizer for liquid product comprising a pair of intensifier cylinder pumps ( ) driven by a hydraulic system ( ). The pumps have a power stroke side and a suction stroke side, and a pair of proximity sensors ( ) that interface with each pump to detect forward and rearward movement. A microprocessor ( ) with timing capabilities controls the sequential operation of each pump with the power stroke of each pump timed to alternately produce a flow of the liquid product with a precisely timed flow overlap period from the alternating pumps. Since the power stroke takes a longer time than the suction stroke, the instant each power stroke is started the opposite pump is timed to hesitate and slightly overlap until a constant product flow-rate is produced from the alternating pumps, which eliminates large variances in pressure and therefore achieves uniformity in product particle size.