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Jaeki K Min, 56Memphis, TN

Jaeki Min Phones & Addresses

Memphis, TN   

2176 Heritage Trace Ct, Marietta, GA 30062    770-5526710   

Long Island City, NY   

Mentions for Jaeki K Min

Jaeki Min resumes & CV records

Resumes

Jaeki Min Photo 14

Staff Scientist At St.jude Children's Research Hospital

Position:
Staff Scientist at St.Jude Children's Research Hospital
Location:
Greater Memphis Area
Industry:
Research
Work:
St.Jude Children's Research Hospital - Greater Memphis Area since Apr 2010
Staff Scientist
St.Jude Children's Research Hospital - Greater Memphis Area Oct 2009 - Apr 2010
Research Lab Specialist
Emory University - Greater Atlanta Area Jan 2007 - Oct 2009
Research Scientist-The Chemical Biology Discovery Center
New York University - Greater New York City Area Aug 2004 - Dec 2006
Postdoctoral Research Associate
JW Pharmaceutical Corporation, C&C Research Labs - South Korea Jan 2003 - Jul 2004
Associate Principal Researcher
JW Pharmaceutical Corporation, C&C Research Labs - South Korea Jan 1991 - Jan 2003
Senior Research Scientist
Education:
Seoul National University 1998 - 2004
Ph.D., Organic Chemistry
Hanyang University 1990 - 1992
M.S., Organic Chemistry
Hanyang University 1986 - 1990
B.S., Chemistry
Interests:
Medicinal Chemistry, Organic Chemistry, Chemical Biology, High-throughput Screening (HTS), Assay Development, Combinatorial Chemistry, Drug Discovery, Chemical Genetics, ADME
Jaeki Min Photo 15

Jaeki Min

Publications & IP owners

Us Patents

S-Triazine Compounds, Pharmaceutical Compositions And Method Of Using The Same

US Patent:
8163748, Apr 24, 2012
Filed:
May 23, 2008
Appl. No.:
12/154696
Inventors:
Neville Robert Kallenbach - Philadelphia PA, US
Young-Tae Chang - Singapore, SG
Zhigang Liu - New York NY, US
Chunhui Zhou - Woodhaven NY, US
Jaeki Min - Marietta GA, US
Assignee:
New York University - New York NY
International Classification:
A61K 31/53
C07D 251/54
C07D 403/00
US Classification:
514245, 544196, 544197, 544198
Abstract:
Novel s-triazine compounds are disclosed that have a formula represented by the following:.

Prostaglandin Transporter Inhibitors

US Patent:
8227466, Jul 24, 2012
Filed:
May 15, 2007
Appl. No.:
12/227267
Inventors:
Victor L. Schuster - New York NY, US
Yuling Chi - Bronx NY, US
Young-Tae Chang - Singapore, SG
Jaeki Min - Marietta GA, US
Assignee:
Albert Einstein College of Medicine of Yeshiva University - Bronx NY
International Classification:
A61K 31/53
C07D 251/54
US Classification:
514245, 544196
Abstract:
Provided are methods of inhibiting prostaglandin transporter (PGT) activity in mammals. Also provided are methods of determining whether a test compound is an inhibitor of a prostaglandin transporter. Additionally provided are compounds that inhibit prostaglandin transporter activity, and pharmaceutical compositions of those compounds. Methods of inhibiting COX-2 in a mammal are also provided. Additionally, methods of treating pain or inflammation in a mammal are provided.

Substituted Triazine Compounds For Nerve Regeneration

US Patent:
2010023, Sep 23, 2010
Filed:
Mar 31, 2008
Appl. No.:
12/594066
Inventors:
John L. Bixby - Miami FL, US
Vance P. Lemmon - Miami FL, US
Young-Tae Chang - Singapore, SG
Jae-Wook Lee - San Diego CA, US
Jaeki Min - Marietta GA, US
Lynn Usher - Cali, CO
International Classification:
A61K 49/00
C07D 403/12
C07D 403/14
C40B 40/04
A61K 31/53
C40B 30/06
A61P 25/00
US Classification:
424 92, 544212, 506 15, 514245, 506 10
Abstract:
A family of substituted triazine compounds is synthesized by combinatorial solid phase chemistry. These compounds were found to increase the growth of neurons/axons from central nervous system neurons that had been damaged, and can be used in methods and pharmaceutical compositions for treating injuries, diseases and conditions associated with nerve damage.

Imaging Agents For Protein Misfolding

US Patent:
2010027, Nov 4, 2010
Filed:
Feb 11, 2008
Appl. No.:
12/029271
Inventors:
Thomas Wisniewski - Staten Island NY, US
Jaeki Min - Marietta GA, US
Qian Li - Frederick MD, US
Young-Tae CHANG - Singapore, SG
Assignee:
NYU - New York NY
International Classification:
G01N 1/30
C07D 401/06
C07D 215/20
C07D 213/57
C07D 209/08
C07C 255/42
C07C 215/68
C07D 295/033
C07D 233/58
C07D 307/79
C07D 307/36
C07D 405/06
C07D 401/14
US Classification:
435 405, 5462774, 546178, 546330, 548469, 546179, 558394, 564443, 544178, 5483435, 549469, 549506
Abstract:
Charged and neutral small fluorescent molecules based upon the styryl scaffold are useful as imaging agents for misfolded proteins such as amyloid plaque. Charged molecules are prepared using pyrrolidine catalyzed reactions by solution-phase synthesis. Neutral styryl molecules are prepared using acetic anhydride catalyzed reactions, Horner-Emmons reactions or Wittig reactions.

Aminoquinoline Derived Heat Shock Protein 90 Inhibitors, Methods Of Preparing Same, And Methods For Their Use

US Patent:
2011028, Nov 17, 2011
Filed:
Oct 6, 2009
Appl. No.:
13/122785
Inventors:
Aiming Sun - Atlanta GA, US
Ganesh Thota - Decatur GA, US
Jaeki Min - Marietta GA, US
Pahk Thepchatri - Atlanta GA, US
Yuhong Du - Atlanta GA, US
James P Snyder - Atlanta GA, US
Dennis C. Liotta - Atlanta GA, US
Assignee:
EMORY UNIVERSITY - Atlanta GA
International Classification:
A61K 31/47
A61K 31/4709
C07D 401/12
C07D 215/38
A61P 35/00
US Classification:
514313, 546171, 514311, 546162
Abstract:
Novel classes of molecular chaperone Heat shock protein 90 (Hsp90) inhibitors and methods for making these classes are provided herein. These compounds are useful in treating and preventing cancer and other Hsp90-related diseases, such as inflammation and neurodegenerative disorders. Also provided herein are methods of treating and preventing cancer and other Hsp90 related disease. The methods include administering to a subject a therapeutically effective amount of an Hsp90 inhibitor.

Heat Shock Protein 90 Inhibitors, Methods Of Preparing Same, And Methods For Their Use

US Patent:
2012002, Jan 26, 2012
Filed:
Oct 6, 2009
Appl. No.:
13/122798
Inventors:
Jaeki Min - Marietta GA, US
Pahk Thepchatri - Atlanta GA, US
Yuhong Du - Atlanta GA, US
Dennis C. Liotta - Atlanta GA, US
Haian Fu - Decatur GA, US
Assignee:
EMORY UNIVERSITY - Atlanta GA
International Classification:
A61K 31/5375
C07D 213/74
C07C 225/30
C07D 239/42
C07D 295/116
C07D 211/14
C07D 295/26
A61K 31/47
A61K 31/44
A61K 31/136
A61K 31/505
A61K 31/451
A61K 31/495
A61P 35/00
A61P 29/00
A61P 25/28
C07D 215/38
US Classification:
5142388, 546171, 546312, 564429, 544332, 544173, 546206, 544395, 544383, 514311, 514352, 514657, 514275, 514319, 51425503
Abstract:
Novel classes of molecular chaperone Heat shock protein 90 (Hsp90) inhibitors are disclosed. These compounds are useful in treating and preventing cancer and other Hsp90-related diseases and conditions, such as inflammation and neurodegenerative disorders. Methods of treating and preventing cancer and other Hsp90 related diseases and conditions are disclosed that include administering to the subject a therapeutically effective amount of an Hsp90 inhibitor. Methods of preparing the novel Hsp90 inhibitors are also provided.

Prostaglandin Transporter Inhibitors

US Patent:
2013017, Jul 4, 2013
Filed:
Jul 23, 2012
Appl. No.:
13/555408
Inventors:
Victor L. Schuster - New York NY, US
Yuling Chi - Bronx NY, US
Young-Tae Chang - Singapore, SG
Jaeki Min - Marietta GA, US
International Classification:
A61K 31/53
G01N 33/68
A61K 31/713
US Classification:
4241721, 514245, 514 44 A, 514 44 R, 506 9, 435 721
Abstract:
The present invention generally relates to prostaglandin transport. More specifically, the invention is directed to compounds that inhibit prostaglandin transport and subsequent COX-2 induction, and methods relating thereto.

Aryl-Substituted Imidazoles

US Patent:
2013034, Dec 26, 2013
Filed:
Sep 30, 2011
Appl. No.:
13/876465
Inventors:
R. Kiplin Guy - Memphis TN, US
Yiqun Zhang - Memphis TN, US
Brandon Young - Memphis TN, US
Michael Dyer - Memphis TN, US
Kristin Finch - Memphis TN, US
Donald Bashford - Memphis TN, US
Nagakumar Bharatham - Memphis TN, US
Richard Kriwacki - Memphis TN, US
Grace Royappa - Memphis TN, US
Lie Min - Memphis TN, US
Jaeki Min - Memphis TN, US
Anthony Ferreira - Germantown TN, US
International Classification:
C07D 403/06
US Classification:
51425405, 544370
Abstract:
The compounds of the invention are antagonists of MDM2 and MDMX, with excellent specificity for MDM2 and MDMX over other proteins, and with selective binding affinity to MDMX over MDM2. The compounds can therefore regulate p53 activity and treat a variety of cancers. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present invention.

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