James E Cullen, 36137 E 26Th St APT 4F, New York, NY 10010

6620900, Sep 16, 2003

Feb 7, 2002

10/071753

Edward G. Malawer - Wayne NJ
James P. Cullen - Bartonsville PA
Chi-San Wu - Wayne NJ
Laurence Senak - Livingston NJ
William J. Drefko - Kearny NJ

ISP Investments Inc. - Wilmington DE

C08F 2608

526264, 526330, 424464

What is described herein is a pharmaceutical excipient which is a proliferous copolymer of vinyl pyrrolidone and vinyl acetate, having advantageous dissolution and disintegration properties.

6806334, Oct 19, 2004

Sep 16, 2003

10/663565

Edward G. Malawer - Wayne NJ
James P. Cullen - Bartonsville PA
Chi-San Wu - Wayne NJ
Laurence Senak - Livingston NJ
William J. Drefko - Kearny NJ
David K. Hood - Basking Ridge NJ
Peter J. Brush - Andover NJ

ISP Investments Inc. - Wilmington DE

C08F 2608

526264, 526330, 424464

What is described herein is an excipient for a pharmaceutical tablet which is a proliferous copolymer of vinyl pyrrolidone and vinyl acetate, to provide the tablet with rapid dissolution and disintegration properties, and, also reduced hygroscopicity.

5597551, Jan 28, 1997

Jan 5, 1995

8/369016

Edward G. Malawer - Wayne NJ
Kolazi S. Narayanan - Wayne NJ
James P. Cullen - Bartonsville PA
Colleen M. Rocafort - Lake Hiawatha NJ

ISP Investments Inc. - Wilmington DE

A61K 711
A61K 9107

424 47

A low volatile organic compound hair spray composition in the form of a stable, clear, single phase microemulsion in which the particles therein have a diameter of less than 1 micron, consisting essentially of by weight, (a) a butyl half-ester of a copolymer of maleic anhydride and ethyl vinyl ether in an amount of about 2-10%, optionally neutralized up to 20 mole %, (b) poly(methyl vinyl ether) as a surface active polymer in an amount of at least 0. 75 to 1 part of (a); (c) a secondary surfactant that is a polyethoxylated glyceryl fatty acid ester in an amount of at least 0. 1%, and which has a hydrophilic-hydrophobic balance of greater than 10, (d) ethanol in an amount of 20 to 50%, and (e) water to 100%.

5458871, Oct 17, 1995

Aug 23, 1994

8/294464

Edward G. Malawer - Wayne NJ
Kolazi S. Narayanan - Palisades Park NJ
James Cullen - Bartonsville PA
Colleen M. Rocafort - Lake Hiawatha NJ

ISP Investments Inc. - Wilmington DE

A61K 711
A61K 706

424 47

A 0% VOC, single phase hair spray composition of a water-insoluble polymer wherein substantially all the particles therein have a diameter of less than 1 micron, i. e. a microemulsion.

5739183, Apr 14, 1998

Sep 13, 1995

8/528380

Chi-San Wu - Wayne NJ
James Curry - Wayne NJ
James P. Cullen - Bartonsville PA
John S. Mc Ewan - Paducah KY

ISP Investments Inc. - Wilmington DE

C08K 516

524239

A method of stabilizing an aqueous solution of an acid copolymer of maleic acid and a C. sub. 1 -C. sub. 5 alkyl vinyl ether against degradation in viscosity or molecular weight upon storage for an extended period of time in aqueous solution at ambient conditions, with a single stabilizing agent, which comprises forming the acid copolymer directly from a slurry of corresponding anhydride in an organic solvent by hydrolysis in water, and adding including ethylenediamine tetraacetic acid (EDTA), or salt thereof, as the single stabilizing agent to the solution either before or after hydrolysis.

5626835, May 6, 1997

Jun 7, 1994

8/255192

Edward G. Malawer - Wayne NJ
Kolazi S. Narayanan - Palisades Park NJ
James Cullen - Bartonsville PA
Colleen M. Rocafort - Lake Hiawatha NJ

ISP Investments Inc. - Wilmington DE

A61K 711

424 47

A low volatile organic compounds hair spray microemulsion in the form of a stable, clear, single phase system in which the particles therein have a diameter of less than 1 micron, consisting essentially of, by weight, (a) an ethyl half-ester of a copolymer of maleic anhydride and an alkyl vinyl ether in an amount of less than 20%, optionally neutralized up to 20 mole %, (b) an ethoxylated glycerol fatty acid ester as the surfactant having a hydrophobic-lipophilic balance of 10-18, in an amount of at least 0. 1%, (c) ethanol in an amount of 55% or less, and (d) water to 100%.

5621136, Apr 15, 1997

Oct 13, 1995

8/542579

Chi-San Wu - Wayne NJ
James Curry - Wayne NJ
James P. Cullen - Bartonsville PA
John S. McEwan - Paducah KY

ISP Investments Inc. - Wilmington DE

C07C 6900
C07C 69007
C07C 6901

560 2

A method of stabilizing an aqueous solution of an acid copolymer of maleic acid and a C. sub. 1 -C. sub. 5 alkyl vinyl ether against degradation in viscosity or molecular weight upon storage for an extended period of time in aqueous solution at ambient conditions, with a single stabilizing agent, which comprises forming the acid copolymer, preferably directly from a slurry of corresponding anhydride in an organic solvent by hydrolysis in water, and adding superoxide dismutase as the single stabilizing agent to the solution either before or after hydrolysis.

5338814, Aug 16, 1994

Apr 21, 1993

8/051107

Chi-San Wu - Wayne NJ
James F. Curry - Wayne NJ
James P. Cullen - Bartonsville PA

ISP Investments Inc. - Wilmington DE

C08F 204
C08F 2610

526210

A process for making polyvinylpyrrolidone (PVP) K-90 having a polydispersity of less than 6, preferably less than 5, and most preferably, less than 4, which comprises polymerizing vinylpyrrolidone monomer by free radical solution polymerization, in water, in the presence of polyethylene glycol (PEG) having a molecular weight of about 300 as a chain transfer agent. The product is an aqueous solution of 15-25% PVP K-90, preferably 20%, 15-30% PEG, preferably 25%, and 45-70% water, preferably 55%, by weight of the solution.