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James Alexander Patch, 46Seattle, WA

Known as:
James A Patch
Related to:
Raeanne D Patch 42 Ralph E Patch 73 Christopher N Breitenbach 32 Elizabeth Breitenbach Jeannine A Breitenbach 63 Katherine E Breitenbach 63 Alyssa K Breitenbach 34 Sean M Breitenbach 40 Katherine E Karle 38 Katie E Breintenbach John J Breitenbach 63 Herman F Breitenbach Catherine R Patch 37

James Patch Phones & Addresses

Seattle, WA   

3337 Birdsall Ave STE 210, Oakland, CA 94619   

Emeryville, CA   

San Francisco, CA   

Oak Park, IL   

Valley Cottage, NY   

Wilmette, IL   

Cornwall on Hudson, NY   

Durham, NC   

Skokie, IL   

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James Patch resumes & CV records

Resumes

James Patch Photo 33

James Patch

James Patch Photo 34

James Patch

James Patch Photo 35

James Patch

James Patch Photo 36

Sr. Engineer, Purification Development At Genentech

Position:
Sr. Engineer, Purification Development at Genentech
Location:
San Francisco Bay Area
Industry:
Biotechnology
Work:
Genentech since Feb 2012
Sr. Engineer, Purification Development Pfizer Jan 2005 - Feb 2012
Staff Engineer II
Education:
Northwestern University 1997 - 2004
Ph.D., Chemical Engineering Duke University 1996 - 1997
James Patch Photo 37

James Patch

Location:
United States
James Patch Photo 38

James Patch

Location:
United States

Publications & IP owners

Us Patents

Shortened Purification Process For The Production Of Capsular Streptococcus Pneumoniae Polysaccharides

US Patent:
2008028, Nov 20, 2008
Filed:
Mar 20, 2008
Appl. No.:
12/052525
Inventors:
Yonghui Yuan - Tappan NY, US
Mark Ruppen - Garnerville NY, US
Wei-Qiang Sun - Morristown NJ, US
Ling Chu - Suffern NY, US
John Simpson - Upper Nyack NY, US
James Patch - Cornwall on Hudson NY, US
Justin Keith Moran - Valley Cottage NY, US
Pamela Fink - New City NY, US
Assignee:
Wyeth - Madison NJ
International Classification:
C12P 19/04
US Classification:
435101
Abstract:
A shortened process for producing a solution containing substantially purified capsular polysaccharides from a cellular lysate broth is described. Ultrafiltering and diafiltering a clarified lysate followed by pH adjustment to less than 4.5, preferably about 3.5, precipitated at least 98% of the protein in the solution without seriously affecting polysaccharide yield. Furthermore, following ultrafiltration and diafiltration and acidification to a pH of less than 4.5, filtration using activated carbon precipitated at least 90% of remaining protein without seriously affecting polysaccharide yield. Exemplary, non-limiting serotypes that can be purified using the shortened process of the invention are 1, 4, 5, 6A, 6B, 7F, 9V, 14, 18C, 19A, 19F, and 23F. In one embodiment, the cells are lysed using deoxycholate sodium (DOC), while in another embodiment the lytic agent is a non-animal derived lytic agent such as N-lauryl sarcosine sodium (NLS).

Selective Poly-Substituted Glycine Antibiotics And Related Compositions

US Patent:
2012029, Nov 22, 2012
Filed:
Feb 6, 2012
Appl. No.:
13/385181
Inventors:
Annelise E. Barron - Palo Alto CA, US
Ronald N. Zuckermann - El Cerrito CA, US
Ann M. Czyzewski - Grayslake IL, US
Michelle T. Dohm - Palos Park IL, US
Tyler M. Miller - Englewood CO, US
James A. Patch - San Francisco CA, US
Nathaniel P. Chongsiriwatana - Chicago IL, US
International Classification:
A01N 37/18
A01P 1/00
US Classification:
514 24
Abstract:
Antimicrobial peptoid compounds and related compositions as can be used against bacteria effectively and selectively.

Selective Poly-N-Substituted Glycine Antibiotics

US Patent:
2014003, Jan 30, 2014
Filed:
May 20, 2013
Appl. No.:
13/898181
Inventors:
Annelise E. Barron - Palo Alto CA, US
Ronald N. Zuckermann - El Cerrito CA, US
Ann M. Czyzewski - Grayslake IL, US
Michelle T. Dohm - Palos Park IL, US
Tyler M. Miller - Englewood CO, US
James A. Patch - San Francisco CA, US
Nathaniel P. Chongsiriwatana - Chicago IL, US
International Classification:
C07K 7/06
US Classification:
530328
Abstract:
Antimicrobial peptoid compounds and related compositions as can be used against bacteria effectively and selectively.

Shortened Purification Process For The Production Of Capsular Streptococcus Pneumoniae Polysaccharides

US Patent:
2015016, Jun 18, 2015
Filed:
Feb 27, 2015
Appl. No.:
14/633141
Inventors:
- New York NY, US
Mark Ruppen - Garnerville NY, US
Wei-Qiang Sun - Morristown NJ, US
Ling Chu - Suffern NY, US
John Simpson - Upper Nyack NY, US
James Patch - Cornwall on Hudson NY, US
Justin Keith Moran - Valley Cottage NY, US
Pamela Fink Charbonneau - New City NY, US
International Classification:
A61K 39/09
Abstract:
A shortened process for producing a solution containing substantially purified capsular polysaccharides from a cellular lysate broth is described. Ultrafiltering and diafiltering a clarified lysate followed by pH adjustment to less than 4.5, preferably about 3.5, precipitated at least 98% of the protein in the solution without seriously affecting polysaccharide yield. Furthermore, following ultrafiltration and diafiltration and acidification to a pH of less than 4.5, filtration using activated carbon precipitated at least 90% of remaining protein without seriously affecting polysaccharide yield. Exemplary, non-limiting S. pneumoniae serotypes that can be purified using the shortened process of the invention are 1, 4, 5, 6A, 6B, 7F, 9V, 14, 18C, 19A, 19F, and 23F. In one embodiment, the cells are lysed using deoxycholate sodium (DOC), while in another embodiment the lytic agent is a non-animal derived lytic agent such as N-lauryl sarcosine sodium (NLS).

Shortened Purification Process For The Production Of Capsular Streptococcus Pneumoniae Polysaccharides

US Patent:
2014036, Dec 11, 2014
Filed:
Jan 24, 2014
Appl. No.:
14/163863
Inventors:
- Madison NJ, US
Mark RUPPEN - Garnerville NY, US
Wei-Qiang SUN - Morristown NJ, US
Ling CHU - Suffern NY, US
John SIMPSON - Upper Nyack NY, US
James PATCH - Cornwall on Hudson NY, US
Justin Keith MORAN - Valley Cottage NY, US
Pamela FINK CHARBONNEAU - New City NY, US
Assignee:
Wyeth LLC - Madison NJ
International Classification:
C07H 1/08
A61K 39/09
US Classification:
42419711, 5361231, 4242441
Abstract:
A shortened process for producing a solution containing substantially purified capsular polysaccharides from a cellular lysate broth is described. Ultrafiltering and diafiltering a clarified lysate followed by pH adjustment to less than 4.5, preferably about 3.5, precipitated at least 98% of the protein in the solution without seriously affecting polysaccharide yield. Furthermore, following ultrafiltration and diafiltration and acidification to a pH of less than 4.5, filtration using activated carbon precipitated at least 90% of remaining protein without seriously affecting polysaccharide yield. Exemplary, non-limiting serotypes that can be purified using the shortened process of the invention are 1, 4, 5, 6A, 6B, 7F, 9V, 14, 18C, 19A, 19F, and 23F. In one embodiment, the cells are lysed using deoxycholate sodium (DOC), while in another embodiment the lytic agent is a non-animal derived lytic agent such as N-lauryl sarcosine sodium (NLS).

Selective Poly-N-Substituted Glycine Antibiotics

US Patent:
2010003, Feb 11, 2010
Filed:
Feb 9, 2009
Appl. No.:
12/378034
Inventors:
Annelise E. Barron - Palo Alto CA, US
Ann M. Czyzewski - Grayslake IL, US
Michelle T. Dohm - Palos Park IL, US
Tyler M. Miller - Aurora CO, US
Ronald N. Zuckermann - El Cerrito CA, US
James A. Patch - Cornwall-on-Hudson NY, US
Nathaniel P. Chongsiriwatana - Albuquerque NM, US
International Classification:
C07K 2/00
US Classification:
530300
Abstract:
Antimicrobial peptoid compounds and related compositions as can be used against bacteria effectively and selectively.

Possible Relatives

David C Patch  Dawn E Patch  Deanna A Patch  Debra L Patch  Daniel D Patch  Aaron Patch  Denise R Patch  James V Johnson  James C Stamps  James E Stanage 

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