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Jasbir S Seehra, 683 Lincoln Ter, Lexington, MA 02421

Known as:
Jasbir Singh Seehra Jasbir Dr Seehra Jasbir J Seehra Jasbirs S Seehra Jasbir Jasbir

Jasbir Seehra Phones & Addresses

3 Lincoln Ter, Lexington, MA 02421    781-8600106   

139 Shade St, Lexington, MA 02421    781-8600106   

6234 Lexington Ridge Dr, Lexington, MA 02421   

Westford, MA   

Tewksbury, MA   

Austin, TX   

Arlington, MA   

Education

Degree: Graduate or professional degree
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Mentions for Jasbir S Seehra

Jasbir Seehra resumes & CV records

Resumes

Jasbir Seehra Photo 8

Jasbir Seehra

Location:
United States
Work:
Achelois BioScience Inc 2011 - 2011
CEO and Founder Acceleron Pharma Feb 2004 - Nov 2010
Founder, Chief Scientific Officer
Education:
University of Southampton 1974 - 1981
BSc and PhD, Biochemistry and Chemistry

Publications & IP owners

Us Patents

Highly Purified Mocarhagin Cobra Venom Protease Polynucleotides Endcoding Same And Related Proteases And Therapeutic Uses Thereof

US Patent:
6413760, Jul 2, 2002
Filed:
Feb 18, 1998
Appl. No.:
09/026001
Inventors:
Amechand Boodhoo - Edmonton, CA
Jasbir S. Seehra - Lexington MA
Gray Shaw - Cambridge MA
Dianne Sako - Boston MA
Assignee:
Genetics Institute, Inc. - Cambridge MA
International Classification:
C12N 964
US Classification:
435226, 526 232, 526 231, 4353201, 435325, 4352523
Abstract:
Highly purified mocarhagin, a cobra venom protease, is disclosed. Pharmaceutical compositions and therapeutic uses of the highly purified protease are also provided. Polynucleotides encoding such protease and related proteases are also disclosed.

Crystalline Il-6 And Models Of The Molecular Structure Of Il-6

US Patent:
6461604, Oct 8, 2002
Filed:
Feb 7, 2000
Appl. No.:
09/499148
Inventors:
William S. Somers - Boston MA
Mark L. Stahl - Wilmington MA
Jasbir S. Seehra - Lexington MA
Thomas E. McDonagh - Acton MA
Jin Hong - Ayer MA
Assignee:
Genetics Institute, LLC - Cambridge MA
International Classification:
C07K 130
US Classification:
424 852, 530351, 530402, 530412, 530418, 530419, 530420, 435 6952
Abstract:
Crystallographic and NMR solution structures of human IL-6 are reported. The invention provides models and systems incorporating such structures which are useful for identifying IL-6/IL-6 receptor interactions and for identification of agonists and antagonists of such interactions. Crystalline human IL-6 is also provided.

Inhibitors Of Phospholipase Enzymes

US Patent:
6500853, Dec 31, 2002
Filed:
Oct 11, 2000
Appl. No.:
09/686616
Inventors:
Jasbir S. Seehra - Lexington MA
John C. McKew - Arlington MA
Frank Lovering - Acton MA
Jean E. Bemis - Arlington MA
YiBin Xiang - Acton MA
Lihren Chen - Cambridge MA
John L. Knopf - Acton MA
Assignee:
Genetics Institute, LLC - Cambridge MA
International Classification:
A61K 31405
US Classification:
514415, 548509, 548250, 514339, 514381, 5462774
Abstract:
This invention concerns compounds and pharmaceutical compositions useful for treating or preventing inflammatory conditions in a mammal, the methods comprising administration of novel pharmaceutically useful compounds of the general formulae: or pharmaceutically acceptable salts thereof, wherein R -R are as defined in the specification.

Inhibitors Of Phospholipase Enzymes

US Patent:
6630496, Oct 7, 2003
Filed:
Aug 24, 2000
Appl. No.:
09/645042
Inventors:
Jasbir S. Seehra - Lexington MA
Neelu Kaila - Natick MA
John C. McKew - Arlington MA
Jean E. Bemis - Arlington MA
YiBin Xiang - Acton MA
Lihren Chen - Cambridge MA
Assignee:
Genetics Institute LLC - Madison NJ
International Classification:
C07D41706
US Classification:
514369, 548181, 548183
Abstract:
This invention provides substituted indole and indoline compounds useful in inhibiting phospholipase activity, particularly including cytosolic phospholipase A2 (cPLA2) activity, as well as pharmaceutical compositions containing the compounds and methods of using them to treat various maladies, including pain and inflammatory conditions.

Crystal Structure Of Cpla2 And Methods Of Identifying Agonists And Antagonists Using Same

US Patent:
6801860, Oct 5, 2004
Filed:
Feb 15, 1999
Appl. No.:
09/250083
Inventors:
Andrea Dessen - Grenoble, FR
William S. Somers - Cambridge MA
Mark L. Stahl - Lexington MA
Jasbir S. Seehra - Lexington MA
Assignee:
Genetics Institute, LLC - Cambridge MA
International Classification:
G06F 9455
US Classification:
702 27, 702 19, 435 19
Abstract:
The present invention provides for crystalline cPLA2. The crystal structure of cPLA2 has also been solved using such material. Models based upon such crystal structure are also provided. Methods of identifying inhibitors of cPLA2 activity and membrane binding using such models are also disclosed.

Inhibitors Of Phospholipase Enzymes

US Patent:
6828344, Dec 7, 2004
Filed:
Sep 29, 2000
Appl. No.:
09/677021
Inventors:
Jasbir S. Seehra - Lexington MA
Neelu Kaila - Natick MA
John McKew - Arlington MA
Frank Lovering - Acton MA
Jean E. Bemis - Arlington MA
YiBin Xiang - Acton MA
Assignee:
Genetics Institute, LLC - Madison NJ
International Classification:
A61K 31404
US Classification:
514415, 546152, 5462774, 548491, 549 29, 549429
Abstract:
Novel compounds are disclosed which inhibit the activity of phospholipase enzymes, particularly cytosolic phospholipase A. Pharmaceutical compositions comprising such compounds and methods of treatment using such compositions are also disclosed.

Highly Purified Mocarhagin, A Cobra Venom Protease, Polynucleotides Encoding Same And Related Proteases, And Therapeutic Uses Thereof

US Patent:
6881404, Apr 19, 2005
Filed:
Nov 27, 2001
Appl. No.:
09/996620
Inventors:
Amechand Boodhoo - Edmonton, CA
Jasbir S. Seehra - Lexington MA, US
Gray Shaw - Cambridge MA, US
Dianne Sako - Boston MA, US
Assignee:
Genetics Institute, LLC - Cambridge MA
International Classification:
A61K038/48
C12N009/64
C12N015/57
US Classification:
424 9467, 435226, 536 232
Abstract:
Highly purified mocarhagin, a cobra venom protease, is disclosed. Pharmaceutical compositions and therapeutic uses of the highly purified protease are also provided. Polynucleotides encoding such protease and related proteases are also disclosed.

Inhibitors Of Phospholipase Enzymes

US Patent:
6916841, Jul 12, 2005
Filed:
May 8, 2002
Appl. No.:
10/075079
Inventors:
Jasbir S. Seehra - Lexington MA, US
Neelu Kaila - Natick MA, US
John C. McKew - Arlington MA, US
Frank Lovering - Acton MA, US
Jean E. Bemis - Arlington MA, US
YiBin Xiang - Acton MA, US
Assignee:
Genetics Institute, LLC - Madison NJ
International Classification:
A61K031/40
C07D209/04
C07D209/18
US Classification:
514419, 548491, 548495
Abstract:
Novel compounds are disclosed which inhibit the activity of phospholipase enzymes in a mammal, particularly cytosolic phospholipase A. Pharmaceutical compositions comprising such compounds and methods of treatment using such compositions are also disclosed.

Possible Relatives

Jasbir Singh  Jasbir S Sethi  Jasbir S Arora  Jasbir K Bains  Jasbir K Dhillon  Jasbir Kaur  Jasbir S Saini  Jasbir S Sidhu  Jasbir Malhotra  Jasbir Cheema 

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