Inventors:
- New York NY, US
John Lance Perez - Doylestown PA, US
Kathrin Ute Jansen - New York NY, US
Paul Liberator - Holmdel NJ, US
Cuiwen Tan - Ridgewood NJ, US
Thomas Richard Jones - Bluffton SC, US
Johannes Frederik Beeslaar - Sandwich, Kent, GB
Judith Absalon - Bronx NY, US
Jason Douglas Maguire - Chesapeake VA, US
Shannon Lea Harris - Boston MA, US
International Classification:
A61K 39/095
A61P 31/04
A61K 47/02
Abstract:
NEW MATERIAL: Recombinant plasmid pTPGIF2 having a size of 4,660 base pairs and a structure obtained by inserting a DNA having a size of 52 base pairs and containing a sequence coding somatostatin into a BamHI incision site of a plasmid vector pTP70-1 capable or fusing a heteropeptide to a carboxy-terminal of a dihydrofolic acid reductase gene of . USE: Producton of fused protein containing somatostatin.PREPARATION: A somatostatin gene is integrated into a plasmid vector pTP70-1. pTPGIF2 is kept in stable state when introduced into . C600 strain. The . C600 train containing pTPGIF2 is deposited in Fermentation Research institute as FERM BP-1577.
