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Jayanthi S Rajagopalan, 64301 Accolade Dr, Cary, NC 27513

Known as:
Jayanthi S R Ramaswamy Jayanthi S Ramaswamy Jay Rajagopalan Jayanthi Rajapopalan Ramaswamy Jayanthi
Related to:
Arvind Ramaswamy

Jayanthi Rajagopalan Phones & Addresses

301 Accolade Dr, Cary, NC 27513    919-4688666   

Washington, DC   

Durham, NC   

Burbank, CA   

Cheltenham, PA   

Milwaukee, WI   

301 Accolade Dr, Cary, NC 27513    919-2253675   

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Position: Food Preparation and Serving Related Occupations
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Mentions for Jayanthi S Rajagopalan

Publications & IP owners

Us Patents

Drug-Oligomer Conjugates With Polyethylene Glycol Components

US Patent:
7030084, Apr 18, 2006
Filed:
Feb 10, 2004
Appl. No.:
10/774903
Inventors:
Nnochiri N. Ekwuribe - Cary NC, US
Muthukumar Ramaswamy - Cary NC, US
Jayanthi Rajagopalan - Cary NC, US
Assignee:
Nobex Corporation - Durham NC
International Classification:
A61K 38/28
C07K 14/62
A61K 38/02
C07K 2/00
US Classification:
514 3, 514 2, 514 21, 530303, 530345, 530410
Abstract:
The present invention relates generally to hydrolyzable drug-oligomer conjugates, pharmaceutical compositions comprising such conjugates, and to methods for making and using such conjugates and pharmaceutical compositions. For example, a conjugate of insulin, PEG, and oleic acid can be orally administered.

Insulin Prodrugs Hydrolyzable In Vivo To Yield Peglylated Insulin

US Patent:
7169889, Jan 30, 2007
Filed:
Jun 19, 2000
Appl. No.:
10/018879
Inventors:
Nnochiri N. Ekwuribe - Cary NC, US
Muthukumar Ramaswamy - Cary NC, US
Jayanthi Rajagopalan - Cary NC, US
Assignee:
Biocon Limited - Bangalore
International Classification:
A61K 38/28
C07K 14/62
US Classification:
530303, 514 3
Abstract:
The present invention relates generally to hydrolyzable drug-oligomer conjugates, pharmaceutical compositions comprising such conjugates, and to methods for making and using such conjugates and pharmaceutical compositions. For example, a conjugate of insulin, PEG, and oleic acid can be orally administered.

Amphiphilic Drug-Oligomer Conjugates With Hydroyzable Lipophile Components And Methods For Making And Using The Same

US Patent:
6309633, Oct 30, 2001
Filed:
Jun 19, 1999
Appl. No.:
9/336548
Inventors:
Nnochiri Ekwuribe - Cary NC
Muthukumar Ramaswamy - Cary NC
Jayanthi Sethuraman Rajagopalan - Cary NC
Assignee:
Nobex Corporation - Research Triangle Park NC
International Classification:
A61K 9107
A61K 3817
A61K 3828
A61K 39385
C07K 1113
US Classification:
424 851
Abstract:
The invention provides a drug-oligomer conjugate having the following general formula: ##STR1## wherein D is a therapeutic drug moiety; H and H' are each a hydrophilic moiety, independently selected from the group consisting of straight or branched PEG polymers having from 2 to 130 PEG subunits, and sugars; L is a lipophilic moiety selected from the group consisting of alkyl groups having 2-26 carbon atoms, cholesterol, adamantane and fatty acids; o is a number from 1 to the maximum number of covalent bonding sites on H; m+n+p together have a value of at least one and not exceeding the total number of covalent bonding sites on D for the --H', --L and --H--L substituents; the H--L bond(s) are hydrolyzable and the D--L' bond(s), when present, are hydrolyzable; the conjugate being further characterized by one of the following: (i) m is 0 and p is at least 1; (ii) n is 0 and p is at least 1; (iii) m and n are each 0 and p is at least 1; (iv) p is 0 and m and n are each at least 1. The therapeutic drug moiety is preferably a therapeutic protein or peptide, preferably insulin or a functional equivalent thereof.

Possible Relatives

Ganesh Rajagopalan  Geetha Rajagopalan  Kannan Rajagopalan  Kavitha K Rajagopalan  Keshav Rajagopalan  Krishnan Rajagopalan  Murali K Rajagopalan 

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