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Jayvardhan Pandit, 66126 High St, Mystic, CT 06355

Jayvardhan Pandit Phones & Addresses

126 High St, Mystic, CT 06355    860-5369722    860-5728423   

12 Water St, Mystic, CT 06355   

Groton, CT   

Norwich, CT   

Berkeley, CA   

126 High St, Mystic, CT 06355    860-5728423   

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Jayvardhan Pandit

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Work

Company: Biopharmaworks May 2018 Position: Director, structural biology

Education

Degree: Doctorates, Doctor of Philosophy School / High School: Indian Institute of Science 1980 to 1985 Specialities: Philosophy

Mentions for Jayvardhan Pandit

Jayvardhan Pandit resumes & CV records

Resumes

Jayvardhan Pandit Photo 11

Director, Structural Biology

Location:
Groton, CT
Work:
Biopharmaworks
Director, Structural Biology
Education:
Indian Institute of Science 1980 - 1985
Doctorates, Doctor of Philosophy, Philosophy

Publications & IP owners

Us Patents

Crystal Structure Of 3', 5'-Cyclic Nucleotide Phosphodiesterase (Pde1B) And Uses Thereof

US Patent:
2005007, Apr 7, 2005
Filed:
Mar 31, 2004
Appl. No.:
10/815390
Inventors:
Jayvardhan Pandit - Mystic CT, US
International Classification:
G06F019/00
G01N033/48
G01N033/50
G01N031/00
US Classification:
702020000
Abstract:
Crystal structures of phosphodiesterase 1B (PDE1B), and the 3-D atomic coordinates of the PDE1B binding domain, are described and used to obtain PDE1B ligands, including PDE1B inhibitors. The inhibitors are formulated into pharmaceutical compositions and used to treat various psychological disorders.

Crystal Structure Of 3', 5'-Cyclic Nucleotide Phosphodiesterase (Pde10A) And Uses Thereof

US Patent:
2005020, Sep 15, 2005
Filed:
Jan 28, 2005
Appl. No.:
11/045860
Inventors:
Jayvardhan Pandit - Mystic CT, US
International Classification:
G06F019/00
G01N033/48
G01N033/50
C12N009/16
US Classification:
435196000, 702019000
Abstract:
Crystal structure of phosphodiesterase 10A (PDE10A), and the 3-D atomic coordinates of the PDE10A binding domain, as described and used for the identification of ligands, including PDE10A inhibitors, used to treat various psychological disorders.

Crystal Structure Of Staphylococcus Undecaprenyl Pyrophosphate Synthase And Uses Thereof

US Patent:
2005020, Sep 22, 2005
Filed:
Oct 17, 2003
Appl. No.:
10/688167
Inventors:
Mark Ammirati - Stonington CT, US
Jayvardhan Pandit - Mystic CT, US
International Classification:
C12N009/12
G06F019/00
G01N033/48
G01N033/50
US Classification:
435194000, 702019000
Abstract:
The invention is directed generally to the structure of prenyltransferases, particularly undecaprenyl pyrophosphate synthase, an enzyme important in bacterial cell wall synthesis. The invention relates to the crystal structure of undecaprenyl pyrophosphate synthase from and the interaction with a cofactor and ligands. The invention also relates to the structure of ligand and cofactor binding sites.

Crystallization Of M-Csf.alpha.

US Patent:
5866114, Feb 2, 1999
Filed:
May 25, 1995
Appl. No.:
8/351292
Inventors:
Jayvardhan Pandit - Mystic CT
Jarmila Jancarik - Walnut Creek CA
Kirston Koths - El Cerrito CA
Robert Halenbeck - San Rafael CA
Anna Lisa Fear - Oakland CA
Eric Taylor - Oakland CA
Ralph Yamamoto - Martinez CA
Andrew Bohm - Berkeley CA
Assignee:
Chiron Corporation - Emeryville CA
International Classification:
A61K 3819
US Classification:
424 851
Abstract:
The present invention is directed to methods for crystallizing macrophage colony stimulating factor (M-CSF) and to a crystalline M-CSF produced thereby. The present invention is also directed to methods for designing and producing M-CSF agonists and antagonists using information derived from the crystallographic structure of M-CSF. The invention is also directed to methods for screening M-CSF agonists and antagonists. In addition, the present invention is directed to an isolated, purified, soluble and functional M-CSF receptor.

Identification Of M-Csf Agonists And Antagonists

US Patent:
6025146, Feb 15, 2000
Filed:
Jun 5, 1995
Appl. No.:
8/462069
Inventors:
Jayvardhan Pandit - Mystic CT
Jarmila Jancarik - Walnut Creek CA
Kirston Koths - El Cerrito CA
Robert Halenbeck - San Rafael CA
Anna Lisa Fear - Oakland CA
Eric Taylor - Oakland CA
Ralph Yamamoto - Martinez CA
Andrew Bohm - Armonk NY
Assignee:
Chiron Corporation - Emeryville CA
International Classification:
G01N 3353
US Classification:
435 72
Abstract:
The present invention is directed to methods for crystallizing macrophage colony stimulating factor. The present invention is also directed to methods for designing and producing M-CSF agonists and antagonists using information derived from the crystallographic structure of M-CSF. The invention is also directed to methods for screening M-CSF agonists and antagonists. In addition, the present invention is directed to an isolated, purified, soluble and functional M-CSF receptor.

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