Inventors:
- Ada MI, US
Jennifer Patterson - Grand Rapids MI, US
Arun Rajgopal - Grand Rapids MI, US
Donald J. Pusateri - Hemet CA, US
Kevin W. Gellenbeck - Poway CA, US
Jeffrey Scholten - Grand Rapids MI, US
Stephen R. Missler - Grand Rapids MI, US
Russell K. Randolph - Anaheim CA, US
Jennifer Chuang - Saratoga CA, US
Yumei Lin - Long Beach CA, US
Valiantsina Kazlova - Stanton CA, US
International Classification:
A61K 36/9066
A61K 36/53
A61K 36/31
A61K 45/06
A61K 31/352
A23L 33/16
A23L 33/105
A23L 2/52
A23L 33/15
A23L 33/155
Abstract:
A supplement including a blend of turmeric, quercetin and rosemary, or holy basil, wasabi, and broccoli seed extract which are present in a balanced and predetermined ratio, and which stimulate the Antioxidant Response Element (ARE), Quinone Reductase, and/or induce related gene expression, for example, heme oxygenase-1 (HMOX-1) expression. The blend of ingredients can be formed as or in a dietary supplement adapted for administration to a subject. The dietary supplement can be formulated so that the turmeric, quercetin and rosemary are present in a predetermined ratio of 1:3:5, or holy basil, wasabi, and broccoli seed extract in a predetermined ratio of 1:1:0.2. Additional ingredients can be included in the supplement. The supplement can synergistically affect natural antioxidant response pathways within cells of a subject to whom the supplement is administered. A related method of use is also provided.
