Jeong P Lee, 83Corona, CA

6520934, Feb 18, 2003

Dec 29, 1999

09/474668

Jeong S. Lee - Diamond Bar CA
Vidya Nayak - Cupertino CA
John Schreiner - Hemet CA
Christine Gutting - Murrieta CA
Edwin Wang - Tustin CA
Gary Heinemann - Campbell CA
Roseminda White - Wildomar CA

Advanced Cardiovascular Systems, Inc. - Santa Clara CA

A61M 2900

6041031

A catheter assembly comprising a shaft and at least one flexible radiopaque marker affixed with the shaft. Flexibility of radiopaque marker is achieved by using a segmented band of radiopaque material or a coiled band formed by winding a wire or hollow tube filled with radiopaque material. The flexible radiopaque marker may be affixed with the shaft by an adhesive, by swaging, by crimping, by soldering, or by spring-action tension fit against the shaft.

6527741, Mar 4, 2003

Dec 21, 1999

09/469966

Jeong S. Lee - Diamond Bar CA
Florencia Lim - Union City CA
Cheryl Stiger - San Diego CA
Carolyn Voyles - Escondido CA
Vincent Bavaro - Temecula CA

Advanced Cardiovascular Systems, Inc. - Santa Clara CA

A61M 2900

60410306, 604509, 606194, 264529

A resizable inflatable balloon, primarily for use with balloon catheters. The resizable inflatable balloon comprises a first portion and an adjacent second portion. The first portion is inflatable to a working diameter at a first pressure while the second portion does not substantially expand at the first pressure. The second portion does expand to the working diameter at a second pressure greater than the first pressure, so that subsequent inflation at the first pressure inflates the first portion and the second portion to the working diameter. The methods of resizing the inflatable members include placing the inflatable balloon in a mold and supplying inflation fluid to expand the second member to the working diameter. In practice, a catheter having the resizable inflatable balloon is guided through a patients vasculature until the inflatable balloon is positioned in a desired region. Inflation fluid is supplied at the first pressure to inflate the first portion to the working diameter.

6530938, Mar 11, 2003

Dec 9, 1999

09/458361

Jeong Soo Lee - Diamond Bar CA
Kenneth L. Wantink - Temecula CA
Alan A. Tannier - Temecula CA
Stephen J. Tiernan - Palo Alto CA

Advanced Cardiovascular Systems, Inc. - Santa Clara CA

A61M 2900

606194, 606191

The invention is directed to a catheter formed at least in part of a multilayered member having a first layer which is fusion bondable to another catheter component such as the skirt of an inflatable balloon and a second layer which is adjacent the first layer having a melting point greater than the first layer so that the multilayered member of the catheter is not deformed when the other catheter component is fusion bonded to the first layer of the multilayered member. The second layer is preferably lubricious in nature. In one embodiment of the invention, the multilayered member is a tubular element with the lubricious second layer defining an inner lumen extending within the tubular element. The outer layer of the tubular member may extend beyond the distal end of the inner layer and form a non-traumatic distal tip. Alternatively, a flexible non-traumatic distal tip may be fusion bonded to at least the outer layer of the multilayered tubular member.

6620127, Sep 16, 2003

Dec 1, 1999

09/451902

Jeong S. Lee - Diamond Bar CA
Timoteo Tomas - Union City CA

Advanced Cardiovascular Systems, Inc. - Santa Clara CA

A61M 2900

604 9601, 606194, 428 369

A balloon catheter having a balloon formed at least in part of a blend of a first polymeric material having a first Shore durometer hardness, and at least a second polymeric material having a second Shore durometer hardness less than the Shore durometer hardness of the first polymeric material. The balloon of the invention has enhanced softness and flexibility due to the presence of the second polymeric material, and a lower than expected compliance. In a presently preferred embodiment, the balloon is formed of a blend of polymeric materials comprising polyether block amides.

6641694, Nov 4, 2003

Dec 22, 1999

09/470075

Jeong S. Lee - Diamond Bar CA

Advanced Cardiovascular Systems, Inc. - Santa Clara CA

B29C 4922

15624414, 264512, 264515, 264516, 264573

An angioplasty balloon and method of manufacture are provided. The balloon has a working length and a taper each having a substantially equivalent thickness. This allows the balloon to be steered easily through vasculature to the site of a stenosis prior to inflation during an angioplasty procedure. The taper thickness in particular is achieved through use of a specially designed multi-tubular slug which is molded to form the angioplasty balloon of the present invention.

6695809, Feb 24, 2004

Sep 13, 1999

09/394653

Jeong S. Lee - Diamond Bar CA

Advanced Cardiovascular Systems, Inc. - Santa Clara CA

A61M 2900

604 9601, 606108

An intraluminal balloon catheter with an elongated shaft, and an inflatable balloon on the shaft which has an inner layer and a discontinuous outer layer formed at least in part of an elastomeric polymeric material. In a presently preferred embodiment, the catheter is a stent delivery catheter with a stent disposed on the balloon in contact with at least a section of the discontinuous outer layer of the balloon. The discontinuous outer layer of the balloon may comprise fibers or strands of the elastomeric material woven into a braided, webbed, meshed, wrapped or wound outer layer of the balloon.

6697667, Feb 24, 2004

May 31, 2001

09/872248

Jeong S. Lee - Diamond Bar CA
Bruce Wilson - Temecula CA
Deborah Kilpatrick - Mountain View CA
Robert Ainsworth - Scotts Valley CA
Bridget A. Hurley - Mountain View CA
Jeffrey T. Ellis - Mountain View CA

Advanced Cardiovascular Systems, Inc. - Santa Clara CA

A61B 502

600479, 600585, 604523, 356336, 385119

An intravascular device for locating a coronary sinus of a patients heart and method of using the same. In one embodiment, the intravascular device includes an elongated member having at least one lumen and at least one optical fiber coupled to the elongated member. The optical fiber has a distal end configured to contact with a blood flow within the patients heart and a proximal end coupled to a laser Doppler velocimetry system for performing a plurality of laser Doppler velocity measurements of the blood flow within the heart to locate the coronary sinus of the heart. Incorporating LDV technology into an intravascular device such as a catheter or a guidewire system provides diagnostic information of the physiologic environment of the lesion before, during, or after a therapeutic procedure.

6712833, Mar 30, 2004

Aug 22, 2001

09/935449

Jeong S. Lee - Diamond Bar CA
Jose A. Romero - Perris CA
Roseminda J. White - Wildomar CA

Advanced Cardiovascular Systems, Inc. - Santa Clara CA

A61M 2900

606194, 606191

A method of forming a catheter component, such as a balloon, in which the component has a thinned skirt section formed by expanding tubing to a radially enlarged outer diameter and then decreasing the inner diameter and the outer diameter of the radially enlarged skirt section before or during bonding of the skirt section to the catheter shaft. The method generally includes blow molding tubing in a balloon mold having a skirt portion with an inner diameter which is larger than an outer diameter of the thinned skirt section of the balloon, so that the balloon mold produces a balloon having a radially enlarged skirt section with a larger outer diameter than is desired for the finished balloon. By then decreasing the diameter of the radially enlarged skirt section, the resulting skirt section is thinned, to provide a balloon catheter having improved flexibility and low profile.