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Jerzy J Golik, 7948 End Rd, Southington, CT 06489

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48 End Rd, Southington, CT 06489    860-2760185   

20 Gretchens Way, Weymouth, MA 02188   

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Jerzy J Golik

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Position: Homemaker

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Degree: High school graduate or higher

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Jerzy Golik

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Us Patents

Water Soluble Prodrugs Of Azole Compounds

US Patent:
6362172, Mar 26, 2002
Filed:
Jan 10, 2001
Appl. No.:
09/757438
Inventors:
Yasutsugu Ueda - Clinton CT
John D. Matiskella - Wallingford CT
Jerzy Golik - Southington CT
Thomas W. Hudyma - Durham CT
Chung-Pin Chen - Madison CT
Assignee:
Bristol-Myers Squibb Company - Princeton NJ
International Classification:
A61K 31375
US Classification:
514 85, 514 86, 514 93, 544337, 544243, 548112
Abstract:
Water-soluble prodrugs of triazole antifungal compounds having a secondary or tertiary hydroxy group are provided. More particularly, new water-soluble triazole antifungal compounds are provided having the general formula wherein A is the non-hydroxy portion of a triazole antifungal compound of the type containing a secondary or tertiary hydroxyl group and R and R are as defined in the specification.

Phosphonooxymethyl Ethers Of Taxane Derivatives

US Patent:
6455575, Sep 24, 2002
Filed:
Jun 6, 1997
Appl. No.:
08/870794
Inventors:
Jerzy Golik - Southington CT
Dolatrai Vyas - Madison CT
John J. Wright - Guilford CT
Henry Wong - Durham CT
John F. Kadow - Wallingford CT
John K. Thottathil - Robbinsville NJ
Wen-Sen Li - Marlboro NJ
Murray A. Kaplan - Syracuse NY
Robert K. Perrone - Liverpool NY
Mark D. Wittman - Cheshire CT
Assignee:
Bristol-Myers Squibb Company - Princeton NJ
International Classification:
A61K 31337
US Classification:
514449, 549510, 549511
Abstract:
The present invention concerns antitumor compounds. More particularly, the invention provides novel taxane derivatives, pharmaceutical compositions thereof, and their use as antitumor agents.

Water-Soluble Prodrugs Of Azole Compounds

US Patent:
2001001, Aug 16, 2001
Filed:
Dec 4, 2000
Appl. No.:
09/729409
Inventors:
Jerzy Golik - Southington CT, US
John Matiskella - Wallingford CT, US
Yasutsugu Ueda - Clinton CT, US
International Classification:
C07F009/6506
C07F009/6518
US Classification:
548/112000, 548/118000
Abstract:
Water soluble prodrugs of azole antifungal agents are provided by quaternizing a nitrogen atom of the azole ring with a phosphonooxymethyl group.

Water-Soluble Prodrugs Of Azole Compounds

US Patent:
2001001, Aug 23, 2001
Filed:
Dec 4, 2000
Appl. No.:
09/729404
Inventors:
Jerzy Golik - Southington CT, US
John Matiskella - Wallingford CT, US
Yasutsugu Ueda - Clinton CT, US
International Classification:
C07F009/6506
C07F009/6518
US Classification:
548/112000, 548/118000
Abstract:
Water soluble prodrugs of azole antifungal agents are provided by quaternizing a nitrogen atom of the azole ring with a phosphonooxymethyl group.

Antitumor Antibiotic Bmy-41339

US Patent:
5028536, Jul 2, 1991
Filed:
Mar 15, 1989
Appl. No.:
7/323648
Inventors:
Jerzy Golik - Southington CT
John Beutler - Braddock Heights MD
Pat Clark - Frederick MD
John Ross - Myersville MD
John Roach - Frederick MD
Gary Muschik - Frederick MD
William B. Lebherz - Woodsboro MD
Assignee:
Bristol-Myers Squibb Company - New York NY
International Classification:
C12P 1900
C12P 1300
C12P 106
US Classification:
435101
Abstract:
An antitumor antibiotic designated BMY-41339 is produced by fermentation of certain strains of Actinomadura verrucosospora. BMY-41339 exhibits antimicrobial activity and also inhibits the growth of tumors in experimental animals.

Esperamicin Derivatives

US Patent:
4837206, Jun 6, 1989
Filed:
Apr 29, 1987
Appl. No.:
7/043916
Inventors:
Jerzy Golik - Southington CT
Assignee:
Bristol-Myers Company - New York NY
International Classification:
A61K 3170
C07H 1504
US Classification:
514 25
Abstract:
Novel N-acetyl derivatives designated N-acetyl-esperamicins A. sub. 1, A. sub. 2 and A. sub. 1b are prepared by acetylating known antitumor antibiotics. The new derivatives exhibit both antimicrobial and antitumor activity and have the structures ##STR1## wherein R. sup. 1 and R. sup. 2 are hydrogen or ##STR2## and R. sup. 3 is --CH(CH. sub. 3). sub. 2 or --CH. sub. 2 CH. sub. 3.

Antitumor Antibiotic

US Patent:
5086045, Feb 4, 1992
Filed:
Aug 24, 1990
Appl. No.:
7/572062
Inventors:
Jerzy Golik - Southington CT
John Beutler - Braddock Heights MD
Pat Clark - Frederick MD
John Ross - Myersville MD
John Roach - Frederick MD
Gary Muschik - Frederick MD
William B. Lebherz - Woodsboro MD
Assignee:
Bristol-Myers Squibb Company - New York NY
International Classification:
A61K 31715
A61K 3170
C07G 1100
C07G 300
US Classification:
514 61
Abstract:
An antitumor antibiotic designated BMY-41339 is produced by fermentation of certain strains of Actinomadura verrucosospora. BMY-41339 exhibits antimicrobial activity and also inhibits the growth of tumors in experimental animals.

Phosphonooxymethyl Ethers Of Taxane Derivatives

US Patent:
5646176, Jul 8, 1997
Filed:
May 19, 1995
Appl. No.:
8/445360
Inventors:
Jerzy Golik - Southington CT
Dolatrai Vyas - Madison CT
John J. Wright - Guilford CT
Henry Wong - Durham CT
John F. Kadow - Wallingford CT
John K. Thottathil - Robbinsville NJ
Wen-Sen Li - Marlboro NJ
Murray A. Kaplan - Syracuse NY
Robert K. Perrone - Liverpool NY
Mark D. Wittman - Cheshire CT
Assignee:
Bristol-Myers Squibb Company - Princeton NJ
International Classification:
A61K 3138
C07D30514
US Classification:
514444
Abstract:
The present invention concerns antitumor compounds. More particularly, the invention provides novel taxane derivatives, pharmaceutical compositions thereof, and their use as antitumor agents.

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