Jia Zheng Li, 814640 E Asbury Cir UNIT 12, Denver, CO 80222

6764822, Jul 20, 2004

Apr 3, 2000

09/541210

John M. Butler - Menlo Park CA
Jia Li - Union City CA
Joseph A. Monforte - Berkeley CA
Christopher H. Becker - Palo Alto CA

Sequenom, Inc. - San Diego CA

C12Q 168

435 6, 435 912, 436 94, 436173, 536 253, 536 254

The present invention is related to the fields of genetic mapping and genetic identity detection, including forensic identification and paternity testing. This invention is more specifically directed to the use of mass spectrometry to detect length variation in DNA nucleotide sequence repeats (including variants of common alleles), such as microsatellites and short tandem repeats, and to DNA sequences provided as primers for the analysis of DNA tandem nucleotide repeat polymorphisms at specific loci on specific chromosomes.

2003015, Aug 21, 2003

Jan 30, 2003

10/354693

Dorothee Foernzler - Lenzburg, CH
Lara Hashimoto - Basle, CH
Jia Li - Union City CA, US
Eric Luedin - Liestal, CH
Andrew Sleight - Riedisheim, FR
Pierre Vankan - Basle, CH

C12Q001/68
A61K031/44
A61K031/541
A61K031/5377

514/227500, 435/006000, 514/235500, 514/357000

The present invention relates to a method for correlating single nucleotide polymorphisms in the preprotachykinin (NKNA) gene with the efficacy and compatibility of a pharmaceutically active compound administered to a human being. The invention further relates to a method for determining the efficacy and compatibility of a pharmaceutically active compound administered to a human being which method comprises determining at least one single nucleotide polymorphism in the NKNA gene. Said methods are based on determining specific single nucleotide polymorphisms in the NKNA gene and determining the efficacy and compatibility of a pharmaceutically active compound in the human by reference to polymorphism in NKNA. The invention further relates to isolated nucleic acids comprising within their sequence the polymorphisms as defined herein, to nucleic acid primers and oligonucleotide probes capable of hybridizing to such nucleic acids and to a diagnostic kit comprising one or more of such primers and probes for detecting a polymorphism in the NKNA gene, to a pharmaceutical pack comprising NK-1 receptor antagonists and instructions for administration of the drug to human beings tested for the polymorphisms as well as to a computer readable medium with the stored sequence information for the polymorphisms in the NKNA gene.

2006001, Jan 19, 2006

Jun 28, 2005

11/170717

Jia Li - Union City CA, US
Russell Higuchi - Alameda CA, US
Sunhee Ro - Foster City CA, US
Gary Peltz - Redmond City CA, US

Roche Molecular Systems., Inc. - Alameda CA

C12Q 1/68
C12P 19/34

435006000, 435091200

The current invention is based on the discovery that the Prol2Ala and VN102 single nucleotide polymorphisms in the PPARγ2 provides a method of determining a susceptibility to osteoporosis by detecting the presence of PPARγ of the alleles.

2006022, Oct 12, 2006

Jun 21, 2006

11/472083

Dorothee Foernzler - Lenzburg, CH
Lara Hashimoto - Basle, CH
Jia Li - Union City CA, US
Eric Luedin - Liestal, CH
Andrew Sleight - Riedisheim, FR
Pierre Vankan - Basle, CH

C12Q 1/68
A61K 31/5377
C07H 21/04

435006000, 514235200, 536023500

The present invention relates to a method for correlating single nucleotide polymorphisms in the preprotachykinin (NKNA) gene with the efficacy and compatibility of a pharmaceutically active compound administered to a human being. The invention further relates to a method for determining the efficacy and compatibility of a pharmaceutically active compound administered to a human being which method comprises determining at least one single nucleotide polymorphism in the NKNA gene. Said methods are based on determining specific single nucleotide polymorphisms in the NKNA gene and determining the efficacy and compatibility of a pharmaceutically active compound in the human by reference to polymorphism in NKNA. The invention further relates to isolated nucleic acids comprising within their sequence the polymorphisms as defined herein, to nucleic acid primers and oligonucleotide probes capable of hybridizing to such nucleic acids and to a diagnostic kit comprising one or more of such primers and probes for detecting a polymorphism in the NKNA gene, to a pharmaceutical pack comprising NK-1 receptor antagonists and instructions for administration of the drug to human beings tested for the polymorphisms as well as to a computer readable medium with the stored sequence information for the polymorphisms in the NKNA gene.

6090558, Jul 18, 2000

Sep 18, 1998

9/157177

John M. Butler - Menlo Park CA
Jia Li - Union City CA
Joseph A. Monforte - Berkeley CA
Christopher H. Becker - Palo Alto CA

Genetrace Systems, Inc. - Alameda CA

C07H 2104
C12P 1934
C12Q 168

435 6

The present invention is related to the fields of genetic mapping and genetic identity detection, including forensic identification and paternity testing. This invention is more specifically directed to the use of mass spectrometry to detect length variation in DNA nucleotide sequence repeats (including variants of common alleles), such as microsatellites and short tandem repeats, and to DNA sequences provided as primers for the analysis of DNA tandem nucleotide repeat polymorphisms at specific loci on specific chromosomes.

2022036, Nov 24, 2022

Aug 3, 2022

17/880531

- San Francisco CA, US
Jia Li - Burlingame CA, US
Maurizio Tarsia - San Carlos CA, US

A24F 40/40
A24F 40/51
A24F 40/10

A vaporizer device includes a cartridge and a vaporizer body. The cartridge includes reservoir configured to hold a vaporizable material. The cartridge further includes a channel extending from the reservoir and having an opening at an end of the channel. The vaporizer body includes a movable block. The vaporizer body further includes a controller configured to actuate the movable block, the actuating of the movable block moving the movable block towards the channel to compress the channel, and the compression of the channel ejects, from the opening, at least a portion of the vaporizable material. The vaporizer body further includes a heating element positioned toward the opening of the channel when the cartridge is coupled with the vaporizer body, the heating element configured to vaporize the portion of the vaporizable material.

2023006, Mar 2, 2023

Oct 24, 2022

18/049098

- Santa Monica CA, US
Yuke Zhu - Stanford CA, US
Ning Xu - Irvine CA, US
Kevin Dechau Tang - Los Angeles CA, US
Jia Li - Marina Del Rey CA, US

H04L 51/10
G06F 16/22
G06F 16/51
G06F 16/583
G06N 20/00
G06F 16/9535
G06F 16/954
G06F 16/2457
G06F 16/951
G06N 3/04
G06N 3/08
G06V 20/00
H04L 51/52

Systems, devices, methods, media, and instructions for automated image processing and content curation are described. In one embodiment a server computer system communicates at least a portion of a first content collection to a first client device, and receives a first selection communication in response, the first selection communication identifying a first piece of content of the first plurality of pieces of content. The server analyzes analyzing the first piece of content to identify a set of context values for the first piece of content, and accesses accessing a second content collection comprising pieces of content sharing at least a portion of the set of context values of the first piece of content. In various embodiments, different content values, image processing operations, and content selection operations are used to curate the content collections.

2023004, Feb 9, 2023

Jan 19, 2022

17/579377

- San Francisco CA, US
Caiming Xiong - Menlo Park CA, US
Jia Li - Mountain View CA, US
Yongjun Chen - Palo Alto CA, US

G06N 3/08
G06N 3/04

A method for providing a neural network system includes performing contrastive learning to the neural network system to generate a trained neural network system. The performing the contrastive learning includes performing first model augmentation to a first encoder of the neural network system to generate a first embedding of a sample, performing second model augmentation to the first encoder to generate a second embedding of the sample, and optimizing the first encoder using a contrastive loss based on the first embedding and the second embedding. The trained neural network system is provided to perform a task.