Jian Z Xu, 4966 Winchester St, Malden, MA 02148

8183864, May 22, 2012

Mar 31, 2010

12/750875

Jian Xu - New Hyde Park NY, US

Siemens Medical Solutions USA, Inc. - Malvern PA

G01V 3/00

324307, 324309

A system for respiratory motion compensated MR imaging or spectroscopy, comprises an MR imaging system. The MR imaging system performs a single imaging scan including, acquiring a first imaging data set representing a spatially localized first imaging region located on a patient diaphragm, using a first RF excitation pulse sequence and by transmitting a nuclei excitation first resonant frequency and receiving data substantially at the first resonant frequency. The MR imaging system derives data representing diaphragm position over a respiratory cycle using the first imaging data set, in the single imaging scan. The MR imaging system in response to determining the diaphragm position is within a predetermined window, acquires a second anatomical imaging data set representing a spatially localized second imaging region using a second RF excitation pulse sequence and by transmitting a nuclei excitation second resonant frequency different to the first resonant frequency and receiving data substantially at the second resonant frequency in the single imaging scan.

8185187, May 22, 2012

Mar 11, 2009

12/402055

Jian Xu - Kew Gardens NY, US

Siemens Medical Solutions USA, Inc. - Malvern PA

A61B 5/05

600413

In the acquisition of magnetic resonance imaging or spectroscopic data, 2D PACE is employed to identify an acceptance or shimming window within which the magnetic resonance data are acquired, and to trigger the acquisition of the magnetic resonance data at the same position of the patient's diaphragm in each respiratory cycle. The patient is thereby allowed to freely breath during the data acquisition procedure, but the acquisition of the magnetic resonance data is always able to take place with the patient's diaphragm in the same physical position in each respiratory cycle.

8334691, Dec 18, 2012

Nov 19, 2009

12/622061

Vivian S. Lee - New York NY, US
Jian Xu - New Hyde Park NY, US

Siemens Medical Solutions USA, Inc. - Malvern PA
New York University - New York NY

G01V 3/00

324306, 324309

In a magnetic resonance imaging method for non-contrast imaging of blood at a region in the subject's body, a first 3D MR image is acquired represented by a first 3D volume data set of the region at a first trigger delay time. The first 3D image is acquired using a substantially 90 excitation pulse followed by a plurality of variable flip angle refocus pulses forming an echo train where the refocus pulses are smaller than or equal to 180. To form the first 3D MR image, multiple MR slices are acquired related to the first trigger delay time to speed up the acquisition of the first image. A second 3D MR image is acquired represented by a second 3D volume data set at the same region using the same steps for acquiring the first 3D MR image except that a second trigger delay time is used which is different than the first trigger delay time. The first 3D volume data set and the second 3D volume data set are subtracted to create a third 3D volume data set. From the third 3D volume data set a 2D substantially maximum intensity projection data set is created which may then be displayed to show the blood at the region.

8542046, Sep 24, 2013

May 4, 2011

13/100669

Eduard Roytman - Newton Centre MA, US
Jian Xu - Westborough MA, US
Rahul R. Shah - Marlborough MA, US
Kambiz R. Munshi - Shrewsbury MA, US
Ronald L. Bedard - Westminster MA, US
Mahalingam Nagarajan - Grafton MA, US

Intel Corporation - Santa Clara CA

H03K 3/017

327175, 327 35, 327108

Described herein are an apparatus, system, and method for compensating voltage swing and duty cycle of a signal on an input-output (I/O) pad of a processor by adjusting the voltage swing and duty cycle of the signal. The apparatus comprises a driver to transmit a signal on an I/O pad, the signal on the I/O pad having a voltage swing and a duty cycle; and an adjustment unit, coupled to the driver, to receive the signal from the I/O pad transmitted by the driver and to generate voltage swing and duty cycle control signals for adjusting the voltage swing and duty cycle of the signal on the I/O pad respectively. Described herein is also an analog-to-digital (A2D) converter for measuring and/or calibrating various signal attributes including current, voltage, and time.

2011026, Oct 27, 2011

Feb 2, 2011

13/019379

Jian Xu - New Hyde Park NY, US

SIEMENS MEDICAL SOLUTIONS USA, INC. - Malvern PA

A61B 5/055

600419

A system for Non-Contrast Agent enhanced MR imaging, includes an MR image acquisition device that acquires first and second datasets representing first and second image slabs individually comprising multiple image slices acquired at fast and slow blood flow portions of a heart cycle and oriented substantially perpendicular in at least one axis to direction of vasculature blood flow, in response to a heart cycle synchronization signal. An image data processor processes imaging datasets representing the first and second image slabs to provide first and second volume datasets representing a 3D volume imaged at the fast blood flow portion and the slow blood flow portion respectively and for providing a difference dataset representing an image difference between the first and second volume datasets and enhancing arterial blood flow. A display processor provides data representing an image showing the enhanced arterial blood flow.

2013011, May 9, 2013

May 9, 2012

13/467219

Jian Xu - New Hyde Park NY, US

SIEMENS MEDICAL SOLUTIONS USA, INC. - Malvern PA

A61B 5/055
A61B 5/0402

600413

A system for cardiac MR imaging receives a heart rate signal representing heart electrical activity. The system, over multiple successive heart cycles, uses multiple MR imaging RF coils in gradient echo imaging a patient heart, synchronized with the heart rate signal and uses an inversion recovery pulse for inverting myocardium tissue MR signal for an individual heart cycle, to acquire, within multiple individual successive portions of an individual heart cycle, corresponding successive multiple patient heart images. An individual image of an individual heart cycle portion is derived from multiple heart image representative data sets comprising a reduced set of k-space data elements acquired using corresponding multiple coils of the RF imaging coils. An image generator generates an MR image of an individual heart cycle portion using the multiple heart image representative data sets comprising the reduced set of k-space data elements.

2022037, Dec 1, 2022

Nov 4, 2020

17/772631

- Cambridge MA, US
Jian Xu - Cambridge MA, US

Jounce Therapeutics, Inc. - Cambridge MA

A61K 39/395
C07K 16/28
A61K 9/00

Methods of treating cancer with anti-PD-1 antibodies are provided.

2020022, Jul 16, 2020

Jun 27, 2018

16/626148

- Basel, CH
Jian Xu - Bedford MA, US
Luigi Manenti - Livingston NJ, US

C07K 16/28
A61K 31/7068
A61K 39/00

Antibody molecules that specifically bind to TIM-3 are disclosed. The antibody molecules can be used to treat or prevent cancerous or infectious conditions and disorders.