Jiang Zhu, 5117 Benton Ave, Staten Island, NY 10305

7893276, Feb 22, 2011

Jun 1, 2010

12/791252

Gary M. Lee - Belmont CA, US
Jiang Zhu - Cupertino CA, US

Roche Palo Alto LLC - South San Francisco CA

C07D 249/12

5482632

The present process provides a improved method for the preparation of alkylsulfanyl substituted triazoles 2 which are useful intermediates in a new process for the preparation of triazolones 20.

8261312, Sep 4, 2012

Jun 27, 2008

12/163916

Jiang Zhu - Stanford CA, US
Kaichuan He - San Jose CA, US
Dipak Punnoran Koroth - San Jose CA, US
Jonathan Lemon - Stoughton WI, US
Anil Thomas - Milpitas CA, US
Xi Xu - Castro Valley CA, US

Cisco Technology, Inc. - San Jose CA

H04N 7/173

725115, 725114, 725 92, 725116

A streaming file is constructed with a file header section that includes a file header object, a media data file descriptor, and an index descriptor. A hinting index section includes a first level hinting index with a linear organization corresponding to timing tick key values. A second level hinting index has a non-sequential organization corresponding to such timing tick key values. A special mark in the second level hinting index indicates that the first level hinting index must be consulted for a next timing tick key value. Such mark is positioned in the last of a sequential run of timing tick key values associated with its entries. A data section that can be put in a separate file, and it accepts media data blocks associated in sequential runs of timing tick key values as its entries. Thus hinting is provided for a non-sequential media data file.

2005003, Feb 17, 2005

Jun 18, 2004

10/871917

Terrence Connolly - Redwood City CA, US
Kieran Durkin - Folsom CA, US
Keshab Sarma - Sunnyvale CA, US
Jiang Zhu - Cupertino CA, US

C07H019/067
C07D045/04

536028510, 544310000

A process for the preparation of a 4′-azido-2′,3′,5′-triacyl-nucleoside compound (I; B=B1; Ris RCO— and Ris RCO—) or a 4′-azidonucleoside compounds (I; B is B1 or B2 and Rand Rare hydrogen and acid addition salts thereof) wherein Rand Rare independently Calkyl or phenyl optionally substituted with 1 to 3 substituents selected from the group consisting of alkyl, alkoxy, halogen, nitro or cyano and Ris selected from the group consisting of hydrogen, Calkyl, Chaloalkyl and halogen, comprising contacting a 5′-iodo compound II with a peracid, RC(O)OOH, an acid RC(O)OH and a phase transfer catalyst and interconverting a uridine B1 to a cytosine B2. The present process provides the 4′-azidonucleosides safely and selectively in high purity with increased efficiency.

2008013, Jun 12, 2008

Oct 10, 2007

11/973748

Steven D. Axt - Menlo Park CA, US
Qingwu Jin - San Jose CA, US
Suguna Rachakonda - Robbinsville NJ, US
Bruce Ross - Plainsboro NJ, US
Keshab Sarma - Sunnyvale CA, US
Justin Vitale - San Mateo CA, US
Jiang Zhu - Cupertino CA, US

C07H 19/06
C07H 13/04
C07D 307/20

536 285, 536115, 549478

The present process provides an improved method for converting 2′-deoxy-2′-fluoro-2′-methyl-D-ribonolactones derivatives to 3-fluoro-3-methyl-2-chlorofuran compounds which are useful for the synthesis of nucleosides and improved processes for the synthesis of the D-ribonolactone compounds.

2010005, Mar 4, 2010

Oct 5, 2007

12/444608

Steven D. Axt - Menlo Park CA, US
Keshab Sarma - Sunnyvale CA, US
Justin Vitale - San Mateo CA, US
Jiang Zhu - Cupertino CA, US
Bruce Ross - Plainsboro NJ, US
Suguna Rachakonda - Robbinsville NJ, US
Qingwu Jin - San Jose CA, US

C07H 19/067

536 285

The present process provides an improved method for the preparation of 4-amino-1-((2R,3R,4R,5R)-3-fluoro-4-hydroxy-5-hydrox-ymethyl-3-methyl-tetrahydro-furan-2-yl)-1H-pyrimidin-2-one of the formula (IV) which is a potent inhibitor of Hepatitis C Virus (HCV) NS5B polymerase.

2013000, Jan 3, 2013

Jul 1, 2011

13/175764

Mattia Pascolini - San Mateo CA, US
Jerzy Guterman - Mountain View CA, US
Jonathan Haylock - Los Angeles CA, US
Jiang Zhu - Sunnyvale CA, US
Peter Jeziorek - Mountain View CA, US

H01Q 1/12

343878

An electronic device may have magnetically mounted antenna structures. The electronic device may have a dielectric member against which one or more antennas are mounted. The dielectric member may be a cover glass layer that covers a display in the electronic device, a dielectric antenna window, or other dielectric structure. Each antenna may have an antenna support structure. Conductive antenna structures for the antenna may be mounted to the antenna support structure. The antennas may be cavity-backed planar inverted-F antennas. Portions of each antenna support structure may be configured to receive magnets. The magnets may be attracted towards ferromagnetic structures mounted on the dielectric member. As the magnets are attracted towards the ferromagnetic structure, the antennas may be held in place against the dielectric member.

2013023, Sep 12, 2013

Mar 12, 2012

13/417827

Paul Quinn - San Francisco CA, US
Jiang Zhu - Sunnyvale CA, US

H04N 7/18

348143, 348E07085

A method is provided in one example embodiment and includes creating a key from a hash of a resource identifier associated with a video object; storing the video object in a distributed hash table with the key; and replicating the video object in the distributed hash table based on a redundancy factor associated with the video object. In more particular embodiments, the method can include fragmenting the video object into segments; creating sub-keys with a hash of resource identifiers associated with each of the segments; storing the segments in the distributed hash table with the sub-keys; and replicating the segments in the distributed hash table based on the redundancy factor.

2014001, Jan 9, 2014

Sep 12, 2013

14/025688

Ana Gonzalez Buenrostro - San Mateo CA, US
Hilary Plake Beck - San Carlos CA, US
Xiaoqi Chen - Palo Alto CA, US
Richard Victor Connors - Pacifica CA, US
Jeffrey Deignan - San Francisco CA, US
Jason Duquette - Millbrae CA, US
John Eksterwicz - San Francisco CA, US
Benjamin Fisher - San Mateo CA, US
Brian Matthew Fox - Brisbane CA, US
Jiasheng Fu - Foster City CA, US
Zice Fu - Foster City CA, US
Felix Gonzalez Lopez De Turiso - San Mateo CA, US
Michael William Gribble - San Francisco CA, US
Dann James Gustin - Half Moon Bay CA, US
Julie Anne Heath - Orinda CA, US
Xin Huang - Wellesley MA, US
Xianyun Jiao - Belmont WA, US
Michael Johnson - San Francisco CA, US
Frank Kayser - San Francisco CA, US
David John Kopecky - San Francisco CA, US
Sujen Lai - Burlingame CA, US
Yihong Li - Millbrae CA, US
Zhihong Li - Millbrae CA, US
Jiwen Liu - Foster City CA, US
Jonathan Dante Low - Tarzana CA, US
Brian Stuart Lucas - San Francisco CA, US
Zhihua Ma - Foster City CA, US
Lawrence R. McGee - Pacifica CA, US
Joel McIntosh - Pacifica CA, US
Dustin McMinn - Pacifica CA, US
Julio Cesar Medina - San Carlos CA, US
Jeffrey Thomas Mihalic - San Francisco CA, US
Steven Howard Olson - Millbrae CA, US
Yosup Rew - Foster City CA, US
Philip Marley Roveto - San Francisco CA, US
Daqing Sun - Foster City CA, US
Xiaodong Wang - Millbrae CA, US
Yingcai Wang - Millbrae CA, US
Xuelei Yan - Foster City CA, US
Ming Yu - Foster City CA, US
Jiang Zhu - Palo Alto CA, US

AMGEN INC. - Thousand Oaks CA

C07D 211/76
C07D 417/12
C07D 413/06
C07D 471/10
C07D 409/04
C07D 401/04
C07D 279/02
C07D 491/08
C07D 498/08
C07D 417/14
C07D 491/153
C07D 417/06
C07D 401/06
C07D 405/04

5142102, 546221, 514327, 544130, 5142355, 546208, 514326, 544 582, 5142278, 546209, 514318, 546210, 546 17, 514278, 546213, 544360, 51425312, 5142362, 546188, 514316, 546207, 544329, 514256, 544 3, 5142222, 544105, 544 11, 5142228, 546 90, 514291, 546216, 544336, 51425505, 544332, 514275, 546198, 514321, 5142305

The present invention provides MDM inhibitor compounds of Formula I,