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Jianying Luo, 55Topsfield, MA

Jianying Luo Phones & Addresses

Topsfield, MA   

Malden, MA   

263 63Rd St, Philadelphia, PA 19139    215-4748751    215-4763790   

Reading, MA   

Medford, MA   

Ipswich, MA   

Wellesley, MA   

Boxford, MA   

Beverly, MA   

Havertown, PA   

263 S 63Rd St, Philadelphia, PA 19139   

Work

Position: Private Household Service Occupations

Mentions for Jianying Luo

Publications & IP owners

Us Patents

Methods And Compositions For Targeting Proteins Of Interest To The Host Cell Envelope

US Patent:
2011009, Apr 28, 2011
Filed:
Aug 14, 2008
Appl. No.:
12/673906
Inventors:
James C. Samuelson - Newburyport MA, US
Jianying Luo - Ipswich MA, US
Assignee:
NEW ENGLAND BIOLABS, INC. - Ipswich MA
International Classification:
G01N 33/573
C07H 21/04
C07K 14/00
C12N 9/96
C12P 21/06
G01N 33/53
C12N 9/16
C12N 15/63
C12N 5/10
US Classification:
435 74, 536 234, 530350, 435188, 435 697, 435 71, 435196, 4353201, 435325
Abstract:
Methods and compositions are provided for producing membrane proteins or toxic proteins from recombinant DNA introduced into a prokaryotic host cell by targeting the expressed proteins to the envelope of the host cell. The methods and compositions utilize a protein vehicle fused to a protein of interest. The fusion protein may contain one or more protease cleavage sites to separate the protein of interest from the protein vehicle either in vivo or in vitro. The protein vehicle is characterized by a membrane-tar peptide and a trans-membrane segment separated by a cytoplasmic amino acid sequence that includes a cytoplasmic affinity-binding domain.

Composition, Method And Kit For Obtaining Purified Recombinant Proteins

US Patent:
2015003, Feb 5, 2015
Filed:
Aug 26, 2011
Appl. No.:
13/821113
Inventors:
James C. Samuelson - Newburyport MA, US
Jianying Luo - Ipswich MA, US
Assignee:
NEW ENGLAND BIOLABS, INC. - Ipswich MA
International Classification:
C12N 9/00
US Classification:
435183, 4352528, 4352891
Abstract:
Compositions relating to a combination of two types of separation matrix; and to variant host cells which contain at least one essential host protein that is fused to an affinity binding tag or has been mutated to replace at least two of a plurality of histidines or basic amino acids are provided. Methods are also provided that relate to isolating a recombinant protein from a lysate.

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