Inventors:
Emad ALKHAWAM - New City NY, US
Mankit Ho - West Nyack NY, US
Jin Qiang Xia - Ridgefield NJ, US
Satheesh Papineni - Harriman NY, US
International Classification:
G01N 33/15
Abstract:
The present invention is directed to devices useful for determining the release profile of a macromolecule from a pharmaceutical composition comprising the macromolecule and methods of using the device. Transport of a macromolecule across a semi-permeable barrier is measured as a function of time using the device, the results of which can correlate with an in vivo release of the macromolecule from a pharmaceutical composition, a bioavailability of the macromolecule, or the stability or purity of the pharmaceutical composition comprising the macromolecule.