Inventors:
Hong ZHAO - Edison NJ, US
Prasanna REDDY - Somerset NJ, US
Ivan HORAK - West Orange NJ, US
Jing XIA - Warren NJ, US
Assignee:
ENZON PHARMACEUTICALS, INC. - Bridgewater NJ
International Classification:
A61K 47/48
C07C 271/22
C07D 403/14
C07H 21/02
C07K 16/00
A61K 31/27
A61K 31/4025
A61K 38/00
A61K 31/7105
A61K 31/496
A61K 39/395
A61K 38/43
C12N 5/00
US Classification:
4241791, 560148, 548520, 530328, 530300, 536 231, 530327, 544357, 435183, 5303911, 514483, 514425, 514 2, 51425211, 424 941, 435375
Abstract:
The present invention provides polymeric conjugates containing positively charged moieties. Methods of making the polymeric delivery systems and methods of treating mammals using the same are also disclosed.