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David R Macmillan, 8711 Juniper Dr, Greystone Park, NJ 07950

David Macmillan Phones & Addresses

11 Juniper Dr, Morris Plains, NJ 07950    973-5398987   

Morristown, NJ   

Reston, VA   

Trenton, NJ   

Pasadena, CA   

Morgan, NJ   

Work

Company: The Costa Law Firm Address:

Mentions for David R Macmillan

Career records & work history

Lawyers & Attorneys

David Macmillan Photo 1

David Macmillan - Lawyer

Office:
The Costa Law Firm
Specialties:
Civil Litigation, Personal Injury, Premises Liability, Commercial Liability, Homeowners Association Law, Directors and Officers Liability, Construction Defects, Insurance
ISLN:
905266549
Admitted:
1984
University:
Santa Clara University, B.A., 1973
Law School:
Monterey College of Law, J.D., 1983

David Macmillan resumes & CV records

Resumes

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David Macmillan

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David Macmillan

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David E Macmillan

Industry:
Computer Software
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David Macmillan

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David Macmillan

David Macmillan Photo 20

Small Business Owner

Work:

Small Business Owner
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David T Tom Macmillan

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David Macmillan

Publications & IP owners

Us Patents

Organo-Cascade Catalysis: One-Pot Production Of Chemical Libraries

US Patent:
2010019, Aug 5, 2010
Filed:
Jul 21, 2008
Appl. No.:
12/670152
Inventors:
David MacMillan - Princeton NJ, US
Assignee:
The Trustees of Princeton University - Princeton NJ
International Classification:
C40B 40/04
C40B 50/00
US Classification:
506 15, 506 23
Abstract:
A method for production of a chemical library is provided, where the method involves: reacting, in a single vessel, a) a plurality, x, of aldehydes and/or ketones; and b) either (i) a plurality, y, of nucleophiles, (ii) a plurality, z, of electrophiles or both (i) and (ii); in the presence of c) a cascade catalyst capable of catalyzing reaction between said plurality of aldehydes and/or ketones and said plurality of nucleophiles, said plurality of electrophiles or both; to obtain a mixture of x-y β-nucleophile substituted aldehydes and/or ketones, xz α-electrophile substituted aldehydes and/or ketones or xyz β-nucleophile substituted, α-electrophile substituted aldehydes and/or ketones; and the chemical libraries thus produced.

Intercellular And Intracellular Proximity-Based Labeling Compositions And Systems

US Patent:
2023010, Mar 30, 2023
Filed:
Feb 26, 2021
Appl. No.:
17/802823
Inventors:
- Princeton NJ, US
Ciaran Seath - Princeton NJ, US
David W.C. MacMillan - Princeton NJ, US
International Classification:
C07D 213/22
C07D 213/56
C07D 213/79
C07D 401/14
C07F 15/00
C09K 11/06
Abstract:
In one aspect, transition metal complexes are described herein having composition and electronic structure for generating reactive labeling intermediates having lifetimes and diffusion radii advantageous for proximity-based labeling of various biomolecular species, including proteins, in intracellular and intercellular environments.

Alpha Alkylation Of Aldehyde With A Polycyclic Olefin

US Patent:
2021014, May 20, 2021
Filed:
Apr 17, 2018
Appl. No.:
16/605309
Inventors:
- GENEVA 8, CH
David W.C. MACMILLAN - Princeton NJ, US
International Classification:
C07C 47/225
C07C 45/69
C07C 47/115
A61K 8/33
A61Q 5/02
A61Q 19/10
B01J 31/22
C11D 3/00
C11D 3/50
A61Q 13/00
C11B 9/00
Abstract:
The alpha alkylation of an aldehyde with a polycyclic olefin followed by a ring opening step is presented in order to provide a compound of formula (I) in the form of any one of its stereoisomers or a mixture thereof and where in R represents a hydrogen atom or Clinear alkyl group; R, R, R, and Rrepresent, when taken separately, independently of each other, a hydrogen atom or a Clinear alkyl group or a Clinear or branched alkyl group; or Rand R, when taken together, represent a Clinear, branched or cyclic alkanediyl group and n is 1 or 2 is presented.

Methods For Modulating Sirtuin Enzymes

US Patent:
2015033, Nov 26, 2015
Filed:
May 4, 2015
Appl. No.:
14/703371
Inventors:
- Princeton NJ, US
Emre Koyuncu - Princeton NJ, US
Hahn Kim - Princeton NJ, US
Ileana Cristea - Princeton NJ, US
David MacMillan - Princeton NJ, US
International Classification:
A61K 31/554
A61K 31/519
A61K 45/06
A61K 31/502
A61K 31/4709
A61K 31/4155
A61K 31/444
A61K 31/4439
A61K 31/42
A61K 31/4178
A61K 31/4164
A61K 31/553
A61K 31/4412
A61K 31/496
A61K 31/4015
A61K 31/415
A61K 31/4725
A61K 31/501
A61K 31/47
Abstract:
This document relates to compounds useful for modulating sirtuin enzymes. For example, the compounds provided herein are useful as broad spectrum antiviral agents. In addition, the compounds provided herein may be used in the treatment of other disorders associated with sirtuin enzymes, such as diseases related to aging and stress, blood clotting disorders, cancer, cardiovascular diseases, diabetes, inflammation, neurodegenerative diseases, and obesity.

Organo-Cascade Catalysis: One-Pot Production Of Chemical Libraries

US Patent:
2014014, May 22, 2014
Filed:
Jan 27, 2014
Appl. No.:
14/165079
Inventors:
- PRINCETON NJ, US
David MACMILLAN - Princeton NJ, US
Assignee:
THE TRUSTEES OF PRINCETON UNIVERSITY - PRINCETON NJ
International Classification:
C07C 45/61
US Classification:
506 27
Abstract:
A method for production of a chemical library is provided, where the method involves: reacting, in a single vessel, a) a plurality, x, of aldehydes and/or ketones; and b) either (i) a plurality, y, of nucleophiles, (ii) a plurality, z, of electrophiles or both (i) and (ii); in the presence of c) a cascade catalyst capable of catalyzing reaction between said plurality of aldehydes and/or ketones and said plurality of nucleophiles, said plurality of electrophiles or both; to obtain a mixture of x-y β-nucleophile substituted aldehydes and/or ketones, x•z α-electrophile substituted aldehydes and/or ketones or x•y•z β-nucleophile substituted, α-electrophile substituted aldehydes and/or ketones; and the chemical libraries thus produced.

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