John O Sewell, 88Alexandria, VA

6491647, Dec 10, 2002

Sep 23, 1999

09/401762

Keith Bridger - Washington DC
Arthur V. Cooke - Baltimore MD
Philip M. Kuhn - Severna Park MD
Joseph J. Lutian - Arnold MD
Edward J. Passaro - Towson MD
John M. Sewell - Cockeysville MD
Terence V. Waskey - Centerville MD
Gregg R. Rubin - Baltimore MD

Active Signal Technologies, Inc. - Cockeysville MD

A61B 502

600585, 600500, 128900

The present invention relates to a non-invasive device for measuring physiological processes. More particularly, it concerns a device that can be applied externally to the body of an animal or human to detect and quantify displacement, force, motion, vibration and acoustic effects resulting from internal biological functions. Specifically, an inexpensive device is disclosed that is compact, light, portable and comfortable, and operates satisfactorily even with imprecise location on the body, ambient noise, motion and light.

6751954, Jun 22, 2004

Nov 4, 2002

10/287269

Keith Bridger - Washington DC, 20002-6023
Arthur V. Cooke - Baltimore MD, 21212
Frank J. Crowne - Laurel MD, 20707
Joseph J. Lutian - Arnold MD, 21012
John M. Sewell - Cockeysville MD, 21030

F16D 3102

60475

A compact hybrid actuator has a fluid pump ( ) arranged to supply fluid to an actuator ( ). The pump has at least one electrically-powered solid-state pump driver ( ) provided with a displacement element ( ). The position of this displacement element modulates the volume of a fluid chamber ( ). A driven valve ( ) is operatively arranged to control the flows of fluid with respect to the pump chamber, and has one member ( ) movable relative to a body ( ) to modulate the opening of ports ( ) so as to form at least one three-way valve. A valve driver ( ) is operatively arranged to operate the driven valve. Electrical power is provided to each valve and to the valve driver so as to operate these various elements in synchronism with one another. The improved pump driver and driven valve may be operated at frequencies in excess of 1 kHz.

6887199, May 3, 2005

Mar 12, 2002

10/095861

Keith Bridger - Washington DC, US
Arthur V. Cooke - Baltimore MD, US
Philip M. Kuhn - Severna Park MD, US
Joseph J. Lutian - Arnold MD, US
Edward J. Passaro - Towson MD, US
John M. Sewell - Cockeysville MD, US
Terence V. Waskey - Centerville MD, US
Gregg R. Rubin - Baltimore MD, US

Active Signal Technologies, Inc. - Linthicum MD

A61B005/00

600300, 128920, 600544

A non-invasive brain assessment monitor is disclosed. An embodiment of the monitor includes a head-mounted brain sensor which passively senses acoustic signals generated from pulsing blood flow through a patient's brain. A reference sensor may be mounted at another location on the patient's body to sense an arterial pulse, and the signals from the brain sensor and reference sensor may be compared. Another embodiment includes transmitters which generate acoustic signals in the brain which are also detected by the brain sensor. The brain assessment monitor may be used to detect conditions such as head trauma, stroke and hemorrhage.

8265291, Sep 11, 2012

Nov 15, 2006

11/599833

Keith Bridger - Washington DC, US
Arthur V. Cooke - Baltimore MD, US
Dennis J. Kohlhafer - Ellicott City MD, US
Joseph J. Lutian - Arnold MD, US
John M. Sewell - Glen Rock PA, US
Richard E. Strite - Germantown MD, US

Active Signal Technologies, Inc. - Linthicum MD

A61B 7/04

381 67, 381423, 600586

A physiological sensing stethoscope suitable for use in high-noise environments is disclosed. The stethoscope is designed to be substantially matched to the mechanical impedance of monitored physiological activity and substantially mismatched to the mechanical impedance of air-coupled acoustic activity. One embodiment of the stethoscope utilizes a passive acoustic system. Another embodiment utilizes an active Doppler system. The passive and active systems can be combined in one stethoscope enabling switching from a passive mode to an active mode suitable for use in very high-noise environments. The stethoscope is suitable for use in environments having an ambient background noise of 100 dBA and higher. The passive includes a head having a housing, a flexural disc mounted with the housing, and an electromechanical stack positioned between the housing and the flexural disc in contact with the skin of a patient. The active system detects Doppler shifts using a high-frequency transmitter and receiver.

2012030, Nov 29, 2012

Aug 8, 2012

13/569835

Keith Bridger - Washington DC, US
Arthur V. Cooke - Baltimore MD, US
Dennis J. Kohlhafer - Ellicott City MD, US
Joseph J. Lutian - Arnold MD, US
John M. Sewell - Glen Rock PA, US
Richard E. Strite - Germantown MD, US

Active Signal Technologies, Inc. - Linthicum MD

A61B 7/04

600586

A physiological sensing stethoscope suitable for use in high-noise environments is disclosed. The stethoscope is designed to be substantially matched to the mechanical impedance of monitored physiological activity and substantially mismatched to the mechanical impedance of air-coupled acoustic activity. One embodiment of the stethoscope utilizes a passive acoustic system. Another embodiment utilizes an active Doppler system. The passive and active systems can be combined in one stethoscope enabling switching from a passive mode to an active mode suitable for use in very high-noise environments. The stethoscope is suitable for use in environments having an ambient background noise of 100 dBA and higher. The passive includes a head having a housing, a flexural disc mounted with the housing, and an electromechanical stack positioned between the housing and the flexural disc in contact with the skin of a patient. The active system detects Doppler shifts using a high-frequency transmitter and receiver.

5919144, Jul 6, 1999

May 6, 1997

8/851796

Keith Bridger - Washington DC
Arthur V. Cooke - Baltimore MD
Frank J. Crowne - Laurel MD
Philip M. Kuhn - Severna Park MD
Joseph J. Lutian - Arnold MD
Edward J. Passaro - Towson MD
John M. Sewell - Cockeysville MD

Active Signal Technologies, Inc. - Cockeysville MD

A61B 500

600561

A non-invasive apparatus and method are disclosed for measuring intracranial pressure. The intracranial measurement system transmits acoustic signals through a cranium and provides an indication of intracranial pressure based on the received acoustic signals after interaction with the brain. Properties such as acoustic transmission impedance, resonant frequency, resonance characteristics, velocity of sound and the like may be measured and correlated with intracranial pressure. The acoustic signals have typical frequencies of less than 100 kHz, for example, in the audible and sub-audible frequency ranges. The intensity of the transmitted acoustic signals used to determine intracranial pressure is relatively low, resulting in little or no health risks during short term or long term monitoring.