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John C Shimko, 496541 Hawthorne St, Columbus, OH 43085

John Shimko Phones & Addresses

6541 Hawthorne St, Columbus, OH 43085    614-4366441   

6552 Hawthorne St, Columbus, OH 43085    570-5469337   

Worthington, OH   

Minneapolis, MN   

Montoursville, PA   

122 Hamburg St, Baltimore, MD 21230    410-8378650   

King of Prussia, PA   

Mechanicsburg, PA   

Lewisburg, PA   

Philadelphia, PA   

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John Shimko

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Us Patents

Methods For Detecting And Quantifying Binding And Inhibition Of Binding Of Species To Nucleic Acids

US Patent:
2003014, Aug 7, 2003
Filed:
Nov 6, 2002
Appl. No.:
10/289057
Inventors:
Jack Summers - Baltimore MD, US
Michael Sturgess - Quakertown PA, US
John Shimko - Baltimore MD, US
International Classification:
C12Q001/68
US Classification:
435/006000
Abstract:
The invention features methods for detecting and quantifying the binding or inhibition of binding of species to biopolymers, e.g., nucleic acids. The invention is based on the use of probes that have magnetic relaxation properties that are affected by the presence of paramagnetic metal ions, e.g., Mn. Any class of biopolymer that binds metal ions at its active site or uses metal ion cofactors can be studied using these methods.

Methods For Detecting And Quantifying Binding And Inhibition Of Binding Of Species To Nucleic Acids

US Patent:
2007009, May 3, 2007
Filed:
May 1, 2006
Appl. No.:
11/415364
Inventors:
Jack Summers - Baltimore MD, US
Michael Sturgess - Quakertown PA, US
John Shimko - Baltimore MD, US
International Classification:
C12Q 1/68
US Classification:
435006000
Abstract:
The invention features methods for detecting and quantifying the binding or inhibition of binding of species to biopolymers, e.g., nucleic acids. The invention is based on the use of probes that have magnetic relaxation properties that are affected by the presence of paramagnetic metal ions, e.g., Mn. Any class of biopolymer that binds metal ions at its active site or uses metal ion cofactors can be studied using these methods.

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