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John M Sorvillo, 7027 Ford Rd, North Sudbury, MA 01776

John Sorvillo Phones & Addresses

27 Ford Rd, Sudbury, MA 01776    978-4436686   

47 Maple Ave UNIT 1001, Sudbury, MA 01776    978-4436686   

19 Washbrook Rd, Sudbury, MA 01776    978-4436686   

Ozone Park, NY   

31 Edith Pl, Merrick, NY 11566   

Elmont, NY   

Mentions for John M Sorvillo

John Sorvillo resumes & CV records

Resumes

John Sorvillo Photo 14

John Sorvillo

Location:
Greater Boston Area
Industry:
Biotechnology
Experience:
Genocea Biosciences (Privately Held; Biotechnology industry): Vice President, Business Development,  (July 2009-August 2010) Altus Pharmaceuticals (Public Company; ALTU; Biotechnology industry): Vice President, Business Development,  (2006-2009) Bi...
John Sorvillo Photo 15

John Sorvillo

John Sorvillo Photo 16

John Sorvillo

Publications & IP owners

Us Patents

Immunoassay For Detection Of Mutant P53 Polypeptide In Serum

US Patent:
6083709, Jul 4, 2000
Filed:
Nov 23, 1993
Appl. No.:
8/094071
Inventors:
Frederick H. Reynolds - Syosset NY
Ron Zeheb - Tucson AZ
John R. Stephenson - Santa Cruz CA
John M. Sorvillo - Sudbury MA
Assignee:
OSI Pharmaceuticals, Inc. - Uniondale NY
International Classification:
G01N 33574
G01N 3353
G01N 33537
G01N 33543
US Classification:
435 794
Abstract:
The invention provides a method for diagnosing in a subject a neoplastic condition which comprises (a) obtaining from the subject a sample of a biological fluid; and (b) detecting the presence in the sample of a mutant p53 polypeptide encoded by an activated p53 oncogene, the presence of the mutant p53 polypeptide in the sample indicating that the subject has the neoplastic condition.

Monoclonal Antibodies Recognizing Parathyroid Hormone-Like Protein

US Patent:
5217896, Jun 8, 1993
Filed:
Dec 30, 1988
Appl. No.:
7/292263
Inventors:
Steven P. Kramer - Kew Gardens NY
David M. Valenzuela - Franklin Square NY
Frederick H. Reynolds - Syosset NY
John M. Sorvillo - Merrick NY
Assignee:
Oncogene Science, Inc. - Uniondale NY
International Classification:
C12N 520
C12N 1502
C07K 1528
C12P 2108
US Classification:
43524027
Abstract:
This invention provides a monoclonal antibody which specifically forms a complex with amino acids 1-87 of PTHLP which does not form a complex with amino acids 1-34 of PTHLP, and which forms a complex with the epitope to which any of the monoclonal antibodies produced by the hybridomas 212-10. 7, (ATCC Accession No. HB9930), 199-999 (ATCC Accession No. HB9929), 199-278 (ATCC Accession No. HB9931), is directed. This invention further provides methods of detecting PTHLP and of diagnosing and treating humoral hypercalcemia of malignancy.

Monoclonal Antibodies Directed To Epitopes Of Human Transforming Growth Factor--.Alpha. And Uses Thereof

US Patent:
5190858, Mar 2, 1993
Filed:
Feb 1, 1989
Appl. No.:
7/304947
Inventors:
John M. Sorvillo - Merrick NY
David M. Valenzuela - Franklin Square NY
Frederick H. Reynolds - Syosset NY
Assignee:
Oncogene Science, Inc. - Uniondale NY
International Classification:
C12Q 100
G01N 3353
US Classification:
435 723
Abstract:
The present invention provides a monoclonal antibody which specifically forms a complex with TGF. alpha. in formalin-fixed, paraffin-embedded tissue sections which has an affinity of a least 10. sup. 7, and which is directed to the epitope to which monoclonal antibody 213-4. 4 (ATCC No. HB9992) is directed. The invention further provides the above-described monoclonal antibody wherein the epitope consists essentially of amino acids 34-43 of TGF. alpha. Additionally, the invention concerns the monoclonal antibody 213-4. 4 (ATCC No. HB9992). The invention also provides a method of detecting TGF. alpha. in tissue sections of a tissue in which normal tissue is characterized by the absence of TGF. alpha. and neoplastic tissue is characterized by the presence of TGF. alpha. in a subset of such neoplastic tissue which comprises contacting the tissue sections with an antibody directed to an epitope on TGF. alpha.

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