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John M Venit, 84820 South Ave, Secane, PA 19018

Related to:
Dawn M Ryan 56 Tarassia J Erony 57

John Venit Phones & Addresses

820 South Ave, Clifton Heights, PA 19018    610-5443974   

820 South Ave #M5, Clifton Heights, PA 19018    610-5443974   

Secane, PA   

3050 Hellerman St, Philadelphia, PA 19149   

2617 Hobson St, Philadelphia, PA 19142    215-4920499   

628 Poplar Ave, Wildwood, NJ 08260    609-5220147   

West Wildwood, NJ   

2522 Brooke Rd, Pennsburg, PA 18073    610-7419828   

Warminster, PA   

Work

Position: Retired

Education

Degree: High school graduate or higher

Emails

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Publications & IP owners

Us Patents

Preparation Of (S)-2-Amino-6,6-Dimethoxyhexanoic Acid Methyl Ester Via Novel Dioxolanes

US Patent:
6248882, Jun 19, 2001
Filed:
Oct 12, 2000
Appl. No.:
9/689209
Inventors:
Jollie D. Godfrey - Trenton NJ
David R. Kronenthal - Yardley PA
Mark D. Schwinden - Holland PA
Sushil K. Srivastava - Dayton NJ
Keith Ramig - Orange NJ
John J. Venit - North Brunswick NJ
Paul A. Jass - Charles City IA
Saibaba Racha - East Syracuse NY
John L. Dillon - East Syracuse NY
Nachimuthu Soundararajan - Kendall Park NJ
Gerald L. Powers - North Brunswick NJ
Atul S. Kotnis - Kendall Park NJ
Assignee:
Bristol-Myers Squibb Co. - Princeton NJ
International Classification:
C07D26702
US Classification:
540490
Abstract:
The glycinamide of the formula ##STR1## is reacted with the dioxolane of the formula ##STR2## wherein L is a leaving group such as iodo, bromo, alkylsulfonyloxy, or arylsulfonyloxy to give the dioxolane of the formula ##STR3## Treating the dioxolane of formula III under aqueous refluxing conditions followed by exchanging the dioxolane acetal with a dimethoxy acetal and introduction of the methyl ester gives (S)-2-amino-6,6-dimethoxyhexanoic acid, methyl ester which is an intermediate in the preparation of the dual inhibitor [4S-[4. alpha. (R*),7. alpha. , 10a. beta. ]]-)octahydro-4-[(2-mercapto-1-oxo-3-phenylpropy)-amino]-5-oxo-7H -pyrido[2,1-b][1,3]thiazepine-7-carboxylic acid. Also disclosed are storage stable salts of (S)-2-amino-6,6-dimethoxyhexanoic acid, methyl ester.

Preparation Of (S)-2-Amino-6,6-Dimethoxyhexanoic Acid Methyl Ester Via Novel Dioxolanes

US Patent:
6329542, Dec 11, 2001
Filed:
Oct 12, 2000
Appl. No.:
9/689215
Inventors:
Jollie D. Godfrey - Trenton NJ
David R. Kronenthal - Yardley PA
Mark D. Schwinden - Holland PA
Sushil K. Srivastava - Dayton NJ
Keith Ramig - Orange NJ
John J. Venit - North Brunswick NJ
Paul A. Jass - Charles City IA
Saibaba Racha - East Syracuse NY
John L. Dillon - East Syracuse NY
Nachimuthu Soundararajan - Kendall Park NJ
Gerald L. Powers - North Brunswick NJ
Atul S. Kotnis - Kendall Park NJ
Assignee:
Bristol-Myers Squibb Co. - Princeton NJ
International Classification:
C07C 6966
US Classification:
560186
Abstract:
The glycinamide of the formula ##STR1## is reacted with the dioxolane of the formula ##STR2## wherein L is a leaving group such as iodo, bromo, alkylsulfonyloxy, or arylsulfonyloxy to give the dioxolane of the formula ##STR3## Treating the dioxolane of formula III under aqueous refluxing conditions followed by exchanging the dioxolane acetal with a dimethoxy acetal and introduction of the methyl ester gives (S)-2-amino-6,6-dimethoxyhexanoic acid, methyl ester which is an intermediate in the preparation of the dual inhibitor [4S-[4. alpha. (R*),7. alpha. ,10a. beta. ]]-octahydro-4-[(2-mercapto-1-oxo-3-ph enylpropyl)-amino]-5-oxo-7H-pyrido[2,1-b][1,3]thiazepine-7-carboxylic acid. Also disclosed are storage stable salts of (S)-2-amino-6, 6-dimethoxyhexanoic acid, methyl ester.

Possible Relatives

Hannah Venit  Ronald P Venit  John M Johnson  John Stamps  John R Stan  John Stanard  John R Stanaway  John R Stanbery  John L Stanbrough  John C Stanchak 

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