Joseph B Dipisa, 61153 Woodcutters Ln, Staten Island, NY 10306

4705517, Nov 10, 1987

Sep 3, 1985

6/772217

Joseph A. DiPisa - Flushing NY

Becton, Dickinson and Company - Franklin Lakes NJ

A61F 206
A61B 1712

623 12

An intravascular prosthesis comprises a lining rolled upon itself around an axis so that it is introducible into a vascular lumen. An inflatable channel is included for unrolling the lining when the prosthesis is positioned within the lumen so that the lining may engage the vascular wall to provide support therefor. An occlusion member is provided for occluding the vascular lumen, when the lining is unrolled, by preventing blood from passing through the prosthesis.

4662885, May 5, 1987

Sep 3, 1985

6/772218

Joseph A. DiPisa - Flushing NY

Becton, Dickinson and Company - Franklin Lakes NJ

A61F 204

623 12

An intravascular prosthesis comprises a lining rolled upon itself around an axis so that it is introducible into a vascular lumen. An inflatable channel is included for unrolling the lining when the prosthesis is positioned within the lumen so that the lining may engage the vascular wall to provide support therefor. A filter is provided for filtering the blood which passes through the prosthesis when the lining is unrolled.

5441539, Aug 15, 1995

Jul 22, 1993

8/096216

Paul G. Alchas - Wayne NJ
Jonathan B. Gabel - Clifton NJ
Stuart K. Williams - Wilmington DE
Bruce E. Jarrell - Philadelphia PA
Deborah G. Rose - Warrington PA
Pauline K. Park - Philadelphia PA
Thomas L. Carter - Philadelphia PA
Frank A. Augello - Cedar Knolls NJ
Joseph A. DiPisa - Wyckoff NJ

Thomas Jefferson University - Philadelphia PA
Becton Dickinson and Company - Franklin Lakes NJ

A61F 206
A01N 102

623 66

Apparatus for depositing a cell product, such as endothelial cell product, in a graft and inserting the graft in a vessel is disclosed. The apparatus preferably comprises a tunneler tube that has a hollow portion for supporting the graft therein, apertures to permit the flow of cell product, and a pointed end cap attached to a distal end of the tunneler tube. The apparatus also has a handle connected to the graft and releaseably connected to a proximal end of the tunneler tube that provides an inlet for cell product and outlet in fluid communication with the lumen of the graft. During deposition, the cell product thus flows through the handle, into the graft and exits through the apertures. During insertion, the tunneler tube is manipulated by the handle to enter a vessel, and is then released from the handle and removed to accommodate anastomoses.

4923464, May 8, 1990

Sep 3, 1985

6/772216

Joseph A. DiPisa - Flushing NY

Becton, Dickinson and Company - Franklin Lakes NJ

A61M 2902

606195

An intravascular prosthesis comprises a lining rolled upon itself around an axis so that it is introducible into a vascular lumen. An inflatable channel is included for unrolling the lining when the prosthesis is positioned within the lumen so that the lining may engage the vascular wall to provide support therefor.

5312380, May 17, 1994

Sep 25, 1992

7/951353

Paul G. Alchas - Wayne NJ
Frank A. Augello - Cedar Knolls NJ
Christopher J. Brooks - Glen Cove NY
Tony A. Cutshall - Boonton NJ
Joseph A. DiPisa - Wyckoff NJ
Stuart K. Williams - Wilmington DE
Jonathan B. Gabel - Clifton NJ
Paul J. Mulhauser - New York NY
Wes Prais - Hewitt NJ
Bruce E. Jarrell - Philadelphia PA
Deborah G. Rose - Warrington PA

Thomas Jefferson University - Philadelphia PA
Becton Dickinson and Company - Franklin Lakes NJ

A61J 100
A61M 100

604319

The invention is an endothelial cell procurement and deposition kit for collecting fat from a patient, processing said fat to produce an endothelial cell deposition product, and depositing said product on the surface of a graft, all under sterile conditions established and maintained within the components of said kit comprised of: fat collection means for collecting subcutaneous fat from a patient; digestion means connectable to said fat collection means to maintain sterility during reception of said fat and for retaining said fat under sterile conditions during rinsing and digestion to produce a digested product; endothelial cell isolation means connectable to said digestion means for maintaining sterile conditions during reception of said digested product and for separating and isolating microvessel endothelial cells from said digested product to produce an endothelial cell product; cell deposition means connectable to said isolation means for maintaining sterile conditions during reception of said endothelial cell product and for depositing said cells on the surface of a graft to be implanted in a patient and facilitating implantation of said endothelial graft into a patient.

D262942, Feb 9, 1982

Jan 30, 1980

6/116917

Joseph A. DiPisa - Lyndhurst NJ

Puritan Industries - Auburn MA

D0901

D 9302

5035708, Jul 30, 1991

May 24, 1989

7/356431

Paul G. Alchas - Wayne NJ
Frank A. Augello - Cedar Knolls NJ
Christopher J. Brooks - Glen Cove NY
Tony A. Cutshall - Boonton NJ
Joseph A. DiPisa - Wyckoff NJ
Stuart K. Williams - Wilmington DE
Jonathan B. Gabel - Clifton NJ
Paul J. Mulhauser - New York NY
Wes Prais - Hewitt NJ
Bruce E. Jarrell - Philadelphia PA
Deborah G. Rose - Warrington PA

Thomas Jefferson University - Philadelphia PA
Becton - Franklin Lakes NJ

A61F 206

623 1

The invention is an endothelial cell procurement and deposition kit for collecting fat from a patient, processing said fat to produce an endothelial cell deposition product, and depositing said product on the surface of a graft, all under sterile conditions established and maintained within the components of said kit comprised of: fat collection means for collecting subcutaneous fat from a patient; digestion means connectable to said fat collection means to maintain sterility during reception of said fat and for retaining said fat under sterile conditions during rinsing and digestion to produce a digested product; endothelial cell isolation means connectable to said digestion means for maintaining sterile conditions during reception of said digested product and for separating and isolating microvessel endothelial cells from said digested product to produce an endothelial cell product; cell deposition means connectable to said isolation means for maintaining sterile conditions during reception of said endothelial cell product and for depositing said cells on the surface of a graft to be implanted in a patient and facilitating implantation of said endothelial graft into a patient.

5372945, Dec 13, 1994

Jul 31, 1992

7/923384

Paul G. Alchas - Wayne NJ
Alfred W. Prais - Hewitt NJ
Bruce E. Jarrell - Tucson AZ
Stuart K. Williams - Tucson AZ
Joseph A. DiPisa - Wyckoff NJ

C12S 300
C12M 140

435267

Methods and apparatus for collecting and processing tissue to produce an endothelial cell product having a vessel for rinsing, draining, digesting and isolating tissue. The vessel has a rinsing and digesting chamber for containing tissue during processing. An inlet in the rinsing and digesting chamber allows entry of rinsing solution and tissue from a liposuction device. A waste chamber in fluid communication with the rinsing and digesting chamber preferably connects with a vacuum source. An isolation chamber is separated from the rinsing and digesting chamber by a screen. An ampule in fluid communication with the isolation chamber includes a pair of ports controlled by valve devices to be selectively in fluid communication with the isolation chamber. After processing, the ampule isolates a pellet of endothelial cells and the valve devices permit the pellet to be in fluid communication with the ports. The method includes providing the vessel, introducing tissue to be processed, orienting the vessel to screen the tissue, introducing an enzyme and agitating to digest the tissue, centrifuging the vessel to transfer the cells from the digested tissue, and isolating the cells for retrieval.