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Joseph HerseyPunta Gorda, FL

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Punta Gorda, FL   

Hingham, MA   

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Joseph Hersey

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United States

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Wilhelm Winternitz

Joseph Hersey Pratt. The Present Status of Hydrotherapy and Other Forms of Physical Therapeutics. Modern Medicine, vol. XIII (1904), no. 1, pp. ...

Us Patents

Doping Agents And Polymeric Compositions Thereof For Controlled Drug Delivery

US Patent:
2015003, Feb 5, 2015
Filed:
Jul 19, 2012
Appl. No.:
14/233570
Inventors:
Mark W. Grinstaff - Brookline MA, US
Jesse Wolinsky - Brookline MA, US
Stefan Yohe - Cambridge MA, US
Jonah Andrew Kaplan - Newton MA, US
Eric John Falde - Maplewood MN, US
Joseph Steven Hersey - Boston MA, US
Assignee:
TRUSTEES OF BOSTON UNIVERSITY ET AL - Boston MA
International Classification:
A61L 31/14
A61L 31/16
A61L 31/06
US Classification:
424400, 514283
Abstract:
Provided herein are 3-dimensional drug-eluting materials comprising biodegradable polymer(s), one or more bioactive agents and entrapped air. Various embodiments of the methods and compositions described herein are based, in part, on the discovery of hydrophobic doping agents that can be used in the manufacture of polymeric drug delivery compositions that permit the encapsulation of air, thereby permitting tunable drug release via controlled air removal. Such compositions are particularly useful for delivering therapeutically effective doses of one or more bioactive agents to a subject over an extended period of time (e.g., days, weeks, or months).

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