Joseph J Kirkland, 9919 Kendall Ct, Wilmington, DE 19803

6482324, Nov 19, 2002

Dec 26, 2001

10/035901

Joseph J. Kirkland - Wilmington DE
Timothy J. Langlois - West Chester PA

Agilent Technologies, Inc. - Palo Alto CA

B01D 1508

210656, 2101982, 2105021, 502408

Highly purified, porous silica microspheres contain functional groups which are capable of selectively binding to reaction impurities, such as excess reactant or reaction by-products, which are contained in a reaction medium. The reaction impurities can thereby be efficiently removed from the reaction medium, providing a convenient method for product purification.

7041623, May 9, 2006

Oct 23, 2002

10/278517

Joseph J. Kirkland - Wilmington DE, US
Timothy J. Langlois - West Chester PA, US

Agilent Technologies, Inc. - Palo Alto CA

B01J 20/00
C02E 1/28

502439, 502408, 502407, 210656, 2101982, 2105021, 427220, 428405

Highly purified, porous silica microspheres contain functional groups which are capable of selectively binding to reaction impurities, such as excess reactant or reaction by-products, which are contained in a reaction medium. The reaction impurities can thereby be efficiently removed from the reaction medium, providing a convenient method for product purification.

7128884, Oct 31, 2006

Oct 28, 2003

10/694918

Joseph J. Kirkland - Wilmington DE, US
Timothy J. Langlois - West Chester PA, US
Qunjie Wang - Hockessin DE, US

Agilent Technologies, Inc. - Palo Alto CA

C01B 33/12
B01J 20/12
B01D 15/08

423335, 502408, 210656

Highly purified, porous silica microspheres contain functional groups which are capable of selectively binding to reaction impurities, such as excess reactant or reaction by-products, which are contained in a reaction medium. The reaction impurities can thereby be efficiently removed from the reaction medium, providing a convenient method for product purification.

2007018, Aug 16, 2007

Feb 13, 2007

11/705629

Joseph J. Kirkland - Wilmington DE, US
Timothy J. Langlois - Wilmington DE, US

C01B 33/26
G01N 30/02
B01D 15/08

4231181, 422 70, 2101982

The present invention relates to microparticles, particularly spherical silica microparticles, which may be useful in liquid chromatography. Specifically, the microparticles include a solid core and an outer porous shell surrounding and irreversibly joined to the core. The shell is composed of a plurality of colloidal nanoparticles, which are applied using an electrostatic multi-multilayering method. The resulting microparticles have a small particle diameter, such as about 1 μm to 3.5 μm, a high particle density, such as about 1.2 g/cc to 1.9 g/cc, and a high surface area, such as about 50 m/g to 165 m/g. These microparticles can be used to form packed beds and liquid chromatographic columns, which are more efficient and rugged than conventional liquid chromatographic columns.

2008027, Nov 13, 2008

Feb 13, 2007

11/705620

Joseph J. Kirkland - Wilmington DE, US
Timothy J. Langlois - Wilmington DE, US

B01D 15/08
B05D 1/36
B32B 15/02

210656, 427202, 42840224

A process for preparing nanoparticle coated surfaces including the steps of electrostatically coating surfaces with polyelectrolyte by exposing the surface to a solution or suspension of polyelectrolyte, removing excess non-bound polyelectrolyte, then further coating the particles with a multi-layer of charged nanoparticles by exposing the polyelectrolyte-coated surface to a fluid dispersion including the charged nanoparticles. The process steps can optionally be repeated thereby adding further layers of polyelectrolyte followed by nanoparticles as many times as desired to produce a second and subsequent layers. The polyelectrolyte has an opposite surface charge to the charged nanoparticles and a molecular weight at the ionic strength of the fluid that is effective so that the first, second, and subsequent layers independently comprise a multiplicity of nanoparticle layers that are thicker than monolayers.

2009029, Dec 3, 2009

Jun 23, 2009

12/489943

Joseph J. Kirkland - Wilmington DE, US
Timothy J. Langlois - Wilmington DE, US

Advanced Materials Technology, Inc. - Wilmington DE

B05D 3/10
B01D 15/08
B32B 1/00

428403, 427301, 2101982

A process for preparing nanoparticle coated surfaces including the steps of electrostatically coating surfaces with polyelectrolyte by exposing the surface to a solution or suspension of polyelectrolyte, removing excess non-bound polyelectrolyte, then further coating the particles with a multi-layer of charged nanoparticles by exposing the polyelectrolyte-coated surface to a fluid dispersion including the charged nanoparticles. The process steps can optionally be repeated thereby adding further layers of polyelectrolyte followed by nanoparticles as many times as desired to produce a second and subsequent layers. The polyelectrolyte has an opposite surface charge to the charged nanoparticles and a molecular weight at the ionic strength of the fluid that is effective so that the first, second, and subsequent layers independently comprise a multiplicity of nanoparticle layers that are thicker than monolayers.

4446015, May 1, 1984

Nov 30, 1981

6/326158

Joseph J. Kirkland - Wilmington DE

E. I. Du Pont de Nemours and Company - Wilmington DE

B03B 562

209155

A free floating plastic channel for sedimentation field flow fractionation is suspended in a centrifuge rotor filled with a compensating liquid. The channel is constructed of a plastic central hub assembly fitted with a plastic outer ring preferably having a lower density than the hub. The outer ring contains a shallow channel on its radially inner surface and is interference-fitted to the inner ring to insure a liquid tight seal at zero force field. With the liquid totally surrounding the hub-outer ring assembly, stresses on the plastic parts are essentially equalized even under high force fields and leakage from the channel at the hub-ring interface is greatly reduced.

4448679, May 15, 1984

Nov 30, 1981

6/326156

Charles H. Dilks - Newark DE
Joseph J. Kirkland - Wilmington DE
Wallace W. Yau - Wilmington DE

E. I. Du Pont de Nemours and Company - Wilmington DE

B03B 562

209155

A plastic ring has a circumferential groove formed in its outer peripheral surface. The ring is fitted in a bowl-type centrifuge rotor such that the ring's outer surface contacts the inner wall of the rotor. The channel is defined by the groove and rotor wall. The rotor is filled with a compensating liquid to reduce centrifugal stress on the plastic and to reduce leakage from the channel.