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Jun Hayashi, 7310200 Savoy Ct, Ellicott, MD 21042

Jun Hayashi Phones & Addresses

10200 Savoy Ct, Ellicott City, MD 21042    410-2030562   

Far Rockaway, NY   

Columbia, MD   

Kissimmee, FL   

Lake Placid, NY   

10200 Savoy Ct, Ellicott City, MD 21042    410-9132164   

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Jun Hayashi

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Work

Company: A&g pharmaceutical/precision antibody service Position: Vp

Education

Degree: Ph.D. School / High School: The University of Connecticut 1976 to 1981 Specialities: Developmental Immunology

Skills

Biotechnology • Biochemistry • Molecular Biology • Drug Discovery • Cell Culture • Life Sciences • Strategic Planning • Data Analysis • Leadership • Strategy • Project Management • Oncology • Research • Clinical Trials • Medical Devices • Science • Product Development • Lifesciences • Clinical Research • Pharmaceutical Industry

Languages

English • Japanese

Industries

Biotechnology

Mentions for Jun Hayashi

Jun Hayashi resumes & CV records

Resumes

Jun Hayashi Photo 25

Vice President A And G Pharmaceutical Inc., President, Precision Antibody

Location:
Ellicott City, MD
Industry:
Biotechnology
Work:
A&G Pharmaceutical/Precision Antibody Service
VP
Univ. of Maryland School of Pharmacy Aug 1995 - Jan 2008
Associate Professor
Education:
The University of Connecticut 1976 - 1981
Ph.D., Developmental Immunology
Skills:
Biotechnology, Biochemistry, Molecular Biology, Drug Discovery, Cell Culture, Life Sciences, Strategic Planning, Data Analysis, Leadership, Strategy, Project Management, Oncology, Research, Clinical Trials, Medical Devices, Science, Product Development, Lifesciences, Clinical Research, Pharmaceutical Industry
Languages:
English
Japanese

Publications & IP owners

Us Patents

Immunomodulatory Compounds

US Patent:
7521463, Apr 21, 2009
Filed:
Jul 31, 2001
Appl. No.:
10/333605
Inventors:
Jun Hayashi - Ellicott City MD, US
Alexander Mackerell - Baltimore MD, US
Assignee:
University of Maryland, Baltimore - Baltimore MD
International Classification:
A01N 37/02
A01N 57/10
A61K 31/19
A61K 31/22
A61K 31/44
A61K 31/225
US Classification:
514345, 514546, 514547, 514568
Abstract:
Compounds are described which modulate the tzrosine kinase activity of p56and signal transduction pathways in which this enzyme is involved. The invention also relates to compounds which have immunomodulatory activity, e. g. , which have immunosuppressant or immunostimulatory activity, and/or which have an antineoplastic effect. The invention further relates to compositions comprising these compounds, and methods of using them. Compounds are described which modulate the tyrosine kinase activity of p56.

Small Molecule Inhibitors Of Lck Sh2 Domain Binding

US Patent:
8476273, Jul 2, 2013
Filed:
Aug 18, 2008
Appl. No.:
12/674685
Inventors:
Jun Hayashi - Ellicott City MD, US
Alexander Mackerell - Baltimore MD, US
Younus Mia - Ellicott City MD, US
Guanjun Xia - Baltimore MD, US
Assignee:
University of Maryland, Baltimore - Baltimore MD
International Classification:
A61K 31/501
A61K 31/44
A61K 31/16
A61K 31/15
US Classification:
51425201, 514299, 514345, 514615, 514639
Abstract:
The present invention provides materials and methods for modulating an immune response. The materials and methods may be used to treat diseases associated with an aberrant immune response. In some embodiments, materials and methods of the invention may be used to treat autoimmune diseases, for example, rheumatoid arthritis.

Immunomodulatory Compounds That Target And Inhibit The Py'binding Site Of Tyrosene Kinase P56 Lck Sh2 Domain

US Patent:
2007009, May 3, 2007
Filed:
Aug 21, 2006
Appl. No.:
11/507038
Inventors:
Alexander Mackerell - Baltimore MD, US
Jun Hayashi - Ellicott City MD, US
International Classification:
A61K 31/427
A61K 31/426
US Classification:
514369000
Abstract:
Small molecular-weight non-peptidic compounds block Lck SH2 domain-dependent interactions. The inhibitors omit phosphotyrosine (pY) or related moieties.

Immunomodulatory Compounds That Target And Inhibit The Py'binding Site Of Tyrosene Kinase P56 Lck Sh2 Domain

US Patent:
2007019, Aug 23, 2007
Filed:
Dec 12, 2003
Appl. No.:
10/582640
Inventors:
Alexander Mackerell - Baltimore MD, US
Jun Hayashi - Ellicott City MD, US
Ashish Nagarsekar - Gaithersburg MD, US
Niu Huang - San Francisco CA, US
Alba Macias - Cambridge, GB
International Classification:
A61K 31/33
US Classification:
424277100, 424184100
Abstract:
Small molecular-weight non-peptidic compounds block Lck SH2 domain-dependent interactions. The inhibitors omit phosphotyrosine (pY) or related moieties.

Materials And Methods For The Development Of An Antigen-Specific Immune Non-Responsiveness State

US Patent:
2012020, Aug 16, 2012
Filed:
Aug 17, 2010
Appl. No.:
13/391127
Inventors:
Jun Hayashi - Columbia MD, US
International Classification:
A61K 39/00
A61P 13/12
A61P 25/00
A61P 37/06
A61K 31/455
A61P 1/00
A61P 5/14
A61P 3/00
A61K 31/195
A61K 31/502
A61P 29/00
A61P 3/10
US Classification:
4241841, 514563, 514248, 514355
Abstract:
The present invention provides materials and methods for making a subject non-responsive to an antigen. Methods of the invention may comprise contacting the subject with the antigen and a compound that induces anergy. In some embodiments, the antigen may be an autoimmune antigen, examples of which include, but are not limited to acetylcholine receptor for myasthenia gravis, glutamic acid decarboxylase for type I diabetes mellitus and rheumatoid factor in rheumatoid arthritis, hi some embodiments, the present invention provides a method of transplanting an organ, tissue, or cells into a subject (e.g., a mammal such as a human).

Materials And Methods For The Development Of An Antigen-Specific Immune Non-Responsiveness State

US Patent:
2021031, Oct 14, 2021
Filed:
Dec 18, 2020
Appl. No.:
17/126706
Inventors:
- Columbia MD, US
Jun Hayashi - Columbia MD, US
International Classification:
A61K 39/00
A61K 31/455
A61K 31/502
A61K 31/609
Abstract:
The present invention provides materials and methods for making a subject non-responsive to an antigen. Methods of the invention may comprise contacting the subject with the antigen and a compound that induces anergy. In some embodiments, the antigen may be an autoimmune antigen, examples of which include, but are not limited to acetylcholine receptor for myasthenia gravis, glutamic acid decarboxylase for type I diabetes mellitus and rheumatoid factor in rheumatoid arthritis. In some embodiments, the present invention provides a method of transplanting an organ, tissue, or cells into a subject (e.g. a mammal such as a human).

Materials And Methods For The Development Of An Antigen-Specific Immune Non-Responsiveness State

US Patent:
2020000, Jan 2, 2020
Filed:
Sep 3, 2019
Appl. No.:
16/558600
Inventors:
- Columbia MD, US
Jun HAYASHI - Columbia MD, US
International Classification:
A61K 39/00
A61K 31/455
A61K 31/502
A61K 31/609
Abstract:
The present invention provides materials and methods for making a subject non-responsive to an antigen. Methods of the invention may comprise contacting the subject with the antigen and a compound that induces anergy. In some embodiments, the antigen may be an autoimmune antigen, examples of which include, but are not limited to acetylcholine receptor for myasthenia gravis, glutamic acid decarboxylase for type I diabetes mellitus and rheumatoid factor in rheumatoid arthritis. In some embodiments, the present invention provides a method of transplanting an organ, tissue, or cells into a subject (e.g. a mammal such as a human).

Materials And Methods For The Development Of An Antigen-Specific Immune Non-Responsiveness State

US Patent:
2016035, Dec 8, 2016
Filed:
Aug 8, 2016
Appl. No.:
15/231234
Inventors:
- Columbia MD, US
Jun HAYASHI - Columbia MD, US
Assignee:
A&G PHARMACEUTICAL, INC - Columbia MD
International Classification:
A61K 39/00
A61K 31/502
A61K 31/455
A61K 31/609
Abstract:
The present invention provides materials and methods for making a subject non-responsive to an antigen. Methods of the invention may comprise contacting the subject with the antigen and a compound that induces anergy. In some embodiments, the antigen may be an autoimmune antigen, examples of which include, but are not limited to acetylcholine receptor for myasthenia gravis, glutamic acid decarboxylase for type I diabetes mellitus and rheumatoid factor in rheumatoid arthritis. In some embodiments, the present invention provides a method of transplanting an organ, tissue, or cells into a subject (e.g. a mammal such as a human).

Isbn (Books And Publications)

Cellular Endocrinology: Hormonal Control Of Embryonic And Cellular Differentiation Proceedings Of The First International Symposium On Cellular Endocrinology, Held In Lake Placid, New York, August 12

Author:
Jun Hayashi
ISBN #:
0845150766

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