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Karyn L Newman, 571340 Arch St, Berkeley, CA 94708

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1340 Arch St, Berkeley, CA 94708    510-5482859   

1715 Sacramento St, Berkeley, CA 94702   

Soda Springs, CA   

San Francisco, CA   

Madison, WI   

Chicago, IL   

Crossville, TN   

Alameda, CA   

1340 Arch St, Berkeley, CA 94708   

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Biotechnology

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Karyn Newman

Location:
San Francisco Bay Area
Industry:
Biotechnology

Publications & IP owners

Us Patents

Biological Control Of Pathogenicity In Microbes That Use Alpha, Beta Unsaturated Fatty Acid Signal Molecules

US Patent:
8247648, Aug 21, 2012
Filed:
Apr 13, 2009
Appl. No.:
12/422825
Inventors:
Karyn L. Newman - Berkeley CA, US
Steven E. Lindow - Walnut Creek CA, US
Assignee:
The Regents of the University of California - Oakland CA
International Classification:
C12N 15/09
C12N 15/82
C12N 15/31
A01H 5/00
US Classification:
800279, 800278, 800288, 800298, 8003202, 800306, 800317
Abstract:
DSF-based microbial pathogens may be controlled by certain methods and compositions. A method of controlling diseases caused in a host organism by pathogenic microbial expression of α,β unsaturated fatty acid signal (DSF) molecules involves inoculating the host organism with a non-pathogenic microbe that disrupts α,β unsaturated fatty acid signal molecule-mediated cell-cell communication by the pathogenic microbe in the host organism. Microbes having protein expression that interferes with α,β unsaturated fatty acid signal molecule-mediated cell-cell communication by the pathogenic microbe in the host organism can be identified and isolated or engineered by transformation with DSF-interference (inhibition or activation) gene or genes. Genes conferring DSF-interference activity can also be expressed in organisms (e. g. , plants) susceptible to diseases caused by microbes that use DSF, resulting in genetically resistant organisms.

Polynucleotides Encoding Isoprenoid Modifying Enzymes And Methods Of Use Thereof

US Patent:
2010021, Aug 26, 2010
Filed:
Jun 29, 2006
Appl. No.:
11/917875
Inventors:
Dae-Kyun Ro - Calgary, CA
Karyn Newman - Berkeley CA, US
Eric M. Paradise - Oakland CA, US
Jay D. Keasling - Berkeley CA, US
Mario Ouellet - El Cerrito CA, US
Rachel Eachus - San Francisco CA, US
Kimberly Ho - Novato CA, US
Timothy Ham - El Cerrito CA, US
International Classification:
A01H 5/00
C07H 21/00
C12N 15/74
C12N 1/19
C12N 5/10
C12P 5/02
C12N 1/21
US Classification:
8003173, 536 232, 4353201, 4352542, 435419, 435167, 43525233, 800295, 800298
Abstract:
The present invention provides isolated nucleic acids comprising nucleotide sequences encoding isoprenoid modifying enzymes, as well as recombinant vectors comprising the nucleic acids. The present invention further provides genetically modified host cells comprising a subject nucleic acid or recombinant vector. The present invention further provides a transgenic plant comprising a subject nucleic acid. The present invention further provides methods of producing an isoprenoid compound, the method generally involving culturing a subject genetically modified host cell under conditions that permit synthesis of an isoprenoid compound modifying enzyme encoded by a subject nucleic acid.

Polynucleotides Encoding Isoprenoid Modifying Enzymes And Methods Of Use Thereof

US Patent:
2012028, Nov 15, 2012
Filed:
Mar 21, 2012
Appl. No.:
13/426387
Inventors:
Dae-Kyun Ro - Calgary, CA
Karyn Newman - Berkeley CA, US
Eric M. Paradise - Oakland CA, US
Jay D. Keasling - Berkeley CA, US
Mario Ouellet - El Cerrito CA, US
Rachel a. Krupa - San Francisco CA, US
Kimberly Ho - Novato CA, US
Timothy Ham - El Cerrito CA, US
International Classification:
C12P 17/18
C12N 15/63
A01H 5/00
C12N 5/10
C12N 1/15
C12N 1/13
C12N 15/53
C12N 1/19
US Classification:
435119, 536 232, 4353201, 4352542, 435348, 435419, 43525411, 4352572, 43525423, 43525421, 43525422, 4352543, 4352546, 4352547, 4352544, 43525233, 43525234, 43525231, 4352523, 800298, 8003173
Abstract:
The present invention provides isolated nucleic acids comprising nucleotide sequences encoding isoprenoid modifying enzymes, as well as recombinant vectors comprising the nucleic acids. The present invention further provides genetically modified host cells comprising a subject nucleic acid or recombinant vector. The present invention further provides a transgenic plant comprising a subject nucleic acid. The present invention further provides methods of producing an isoprenoid compound, the method generally involving culturing a subject genetically modified host cell under conditions that permit synthesis of an isoprenoid compound modifying enzyme encoded by a subject nucleic acid.

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