Inventors:
Dae-Kyun Ro - Calgary, CA
Karyn Newman - Berkeley CA, US
Eric M. Paradise - Oakland CA, US
Jay D. Keasling - Berkeley CA, US
Mario Ouellet - El Cerrito CA, US
Rachel a. Krupa - San Francisco CA, US
Kimberly Ho - Novato CA, US
Timothy Ham - El Cerrito CA, US
International Classification:
C12P 17/18
C12N 15/63
A01H 5/00
C12N 5/10
C12N 1/15
C12N 1/13
C12N 15/53
C12N 1/19
US Classification:
435119, 536 232, 4353201, 4352542, 435348, 435419, 43525411, 4352572, 43525423, 43525421, 43525422, 4352543, 4352546, 4352547, 4352544, 43525233, 43525234, 43525231, 4352523, 800298, 8003173
Abstract:
The present invention provides isolated nucleic acids comprising nucleotide sequences encoding isoprenoid modifying enzymes, as well as recombinant vectors comprising the nucleic acids. The present invention further provides genetically modified host cells comprising a subject nucleic acid or recombinant vector. The present invention further provides a transgenic plant comprising a subject nucleic acid. The present invention further provides methods of producing an isoprenoid compound, the method generally involving culturing a subject genetically modified host cell under conditions that permit synthesis of an isoprenoid compound modifying enzyme encoded by a subject nucleic acid.