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Keith A Oberg, 5924347 Crestview Dr, Santa Clarita, CA 91321

Keith Oberg Phones & Addresses

24347 Crestview Dr, Newhall, CA 91321    661-2547667   

25850 El Gato Pl, Valencia, CA 91355   

Santa Clarita, CA   

Watsonville, CA   

123 Carl Ave, Santa Cruz, CA 95062   

Princeville, HI   

Sylmar, CA   

Mentions for Keith A Oberg

Keith Oberg resumes & CV records

Resumes

Keith Oberg Photo 34

Consultant

Location:
Los Angeles, CA
Industry:
Medical Devices
Work:
Alfred Mann Foundation since Mar 2012
Principal Scientist
Infusion Systems (Alfred Mann Foundation) Nov 2005 - Mar 2012
Manager, Pharmaceutics
MannKind Corporation 2001 - 2005
Principal Scientist
Minimed - MRG 2000 - 2001
Senior Scientist
University of California, Santa Cruz Apr 1999 - Oct 2000
Postdoctoral Scientist VII
Free University of Brussels (ULB) Jan 1996 - Mar 1999
Chercheur Libre (Free Researcher)
Education:
University of California, Santa Cruz 1985 - 1994
Ph.D., Chemsitry (Biophysical)
Skills:
R&D, Team Leadership, Product Development, Project Planning, Cross Functional Team Leadership, Biotechnology, Multidisciplinary Design, Protein Chemistry, Medical Diagnostics, Chemistry, Drug Delivery, Medical Devices, Validation, Analytical Chemistry, V&V, Fda, Cross Functional Problem Solving, Team Management, Mass Spectrometry, Cgmp Practices, Pharmaceutical Industry, Formulation, Spectroscopy, Quality System, Research and Development, Life Sciences, U.s. Food and Drug Administration, Project Management, Intellectual Property
Interests:
Classical Music
Macro and Micro
Barbershop Quartetting
Science
Outdoor Adventures
Photography
The Desert In Springtime
Woodworking
Keith Oberg Photo 35

Keith Oberg

Publications & IP owners

Us Patents

Method Of Drug Formulation Based On Increasing The Affinity Of Active Agents For Crystalline Microparticle Surfaces

US Patent:
7803404, Sep 28, 2010
Filed:
Sep 14, 2006
Appl. No.:
11/532065
Inventors:
Mark Hokenson - Valencia CA, US
Keith A. Oberg - Valencia CA, US
Assignee:
MannKind Corporation - Valencia CA
International Classification:
A61K 9/14
A61K 9/28
A61K 38/28
US Classification:
424489, 424490, 424491, 424499, 424434, 514 2, 514 3
Abstract:
Methods are provided for promoting the adsorption of an active agent to microparticles by modifying the structural properties of the active agent in order to facilitate favorable association to the microparticle.

Barrier Catheter Apparatus And Method

US Patent:
7875008, Jan 25, 2011
Filed:
Aug 23, 2004
Appl. No.:
10/924519
Inventors:
Colin Chong - Glendale CA, US
Keith Oberg - Valencia CA, US
Paul Mounce - Burbank CA, US
Peter C. Lord - Valencia CA, US
William P. Van Antwerp - Valencia CA, US
Assignee:
Medtronic Minimed, Inc. - Northridge CA
International Classification:
A61M 5/00
A61M 25/18
US Classification:
604247, 604264, 604537
Abstract:
A catheter for use in delivery or withdrawal of a formulation, wherein the catheter has an outer layer comprising a bio-compatible material and a barrier layer comprising a material that provides a more effective barrier than the outer layer against inward and outward diffusion of substances that may cause destabilization of the formulation. The catheter may include a flared distal end tip to aid in the release, during a bolus delivery or catheter flush, of any obstruction situated at the distal end tip of the catheter. The catheter may also include a slit valve at the distal end tip which has one or more and, preferably a plurality of slits that may be elastically extended to an open position by the expulsion of the formulation during an IIP pump stroke. During the interval between IIP pump strokes, the slits return to a closed position and hinder the inflow of body fluid into the distal end tip.

Valves, Valved Fluid Transfer Devices And Ambulatory Infusion Devices Including The Same

US Patent:
8251960, Aug 28, 2012
Filed:
Mar 24, 2008
Appl. No.:
12/054009
Inventors:
Susan McConnell - Woodland Hills CA, US
Keith A. Oberg - Valencia CA, US
Lawrence S. Ring - Valencia CA, US
Peter C. Lord - Kihei HI, US
Assignee:
The Alfred E. Mann Foundation For Scientific Research - Santa Clarita CA
International Classification:
A61M 5/00
US Classification:
604249
Abstract:
Valves, valved fluid transfer devices and ambulatory infusion devices including the same. The valves includes a valve element and a valve seat, and one of the valve seat and the valve element includes a main portion and a seal portion that is less tacky than the main portion.

Method Of Drug Formulation Of Compositions Comprising Crystalline Microparticle Surfaces

US Patent:
8420604, Apr 16, 2013
Filed:
Jun 14, 2010
Appl. No.:
12/815276
Inventors:
Mark Hokenson - Valencia CA, US
Keith A. Oberg - Valencia CA, US
Assignee:
Mannkind Corporation - Valencia CA
International Classification:
A61K 38/13
A61K 9/14
A61K 9/28
A61P 37/04
US Classification:
514 205, 424490
Abstract:
Methods are provided for promoting the adsorption of an active agent to microparticles by modifying the structural properties of the active agent in order to facilitate favorable association to the microparticle.

Valves, Valved Fluid Transfer Devices And Ambulatory Infusion Devices Including The Same

US Patent:
8551055, Oct 8, 2013
Filed:
Aug 24, 2012
Appl. No.:
13/594737
Inventors:
Susan McConnell - Woodland Hills CA, US
Keith A. Oberg - Valencia CA, US
Lawrence S. Ring - Valencia CA, US
Peter C. Lord - Kihei HI, US
Assignee:
The Alfred E. Mann Foundation for Scientific Research - Santa Clarita CA
International Classification:
A61M 5/00
US Classification:
604249
Abstract:
An ambulatory medical device including a reservoir, a fluid transfer device operably connected to the reservoir, and a pressure regulator that has a valve seat and a valve element movable between a closed position where the valve element engages the valve seat and prevents fluid flow and an open position where the valve element is in spaced relation to the valve seat and does not prevent fluid flow. One of the valve seat and the valve element includes a main portion and a seal portion that is less tacky than the main portion and is engaged by the other of the valve seat and the valve element when the valve element is in the closed position.

Barrier Catheter Apparatus And Method

US Patent:
2003006, Mar 27, 2003
Filed:
Dec 28, 2001
Appl. No.:
10/036081
Inventors:
Colin Chong - Glendale CA, US
Keith Oberg - Valencia CA, US
Paul Mounce - Burbank CA, US
Peter Lord - Valencia CA, US
William Van Antwerp - Valencia CA, US
International Classification:
A61M031/00
A61M025/00
US Classification:
604/523000, 138/137000
Abstract:
A catheter for use in delivery or withdrawal of a formulation, wherein the catheter has an outer layer comprising a bio-compatible material and a barrier layer comprising a material that provides a more effective barrier than the outer layer against inward and outward diffusion of substances that may cause destabilization of the formulation. The outer surface of the barrier layer contacts at least a portion of the inner surface of the outer layer. The catheter may include a flared distal end tip to aid in the release, during a bolus delivery or catheter flush, of any obstruction situated at the distal end tip of the catheter. The larger cross-sectional area at the flared distal end tip minimizes the chances that any obstruction that develops at the distal end tip will be sufficient to hinder the flow of the formulation within the lumen of the catheter. The catheter may also include a slit valve at the distal end tip which has one or more and, preferably a plurality of slits that may be elastically extended to an open position by the expulsion of the formulation during an IIP pump stroke. During the interval between IIP pump strokes, the slits return to a closed position and hinder the inflow of body fluid into the distal end tip.

Method Of Drug Formulation Based On Increasing The Affinity Of Crystalline Microparticle Surfaces For Active Agents

US Patent:
2007005, Mar 15, 2007
Filed:
Sep 14, 2006
Appl. No.:
11/532063
Inventors:
Keith Oberg - Valencia CA, US
International Classification:
A61K 9/28
A61K 38/28
US Classification:
424489000, 514003000, 427002140
Abstract:
Methods are provided for coating crystalline microparticles with an active agent by altering the surface properties of the microparticles in order to facilitate favorable association on the microparticle by the active agent. Type of surface properties that are altered by the disclosed methods include by electrostatic properties, hydrophobic properties and hydrogen bonding properties.

Glucagon-Like Peptide 1 (Glp-1) Pharmaceutical Formulations

US Patent:
2008026, Oct 23, 2008
Filed:
Apr 16, 2007
Appl. No.:
11/735957
Inventors:
Mark J. Hokenson - Valencia CA, US
David Brandt - Valencia CA, US
Mark King - Pasadena CA, US
Stephanie Greene - Ventura CA, US
Mary Faris - Los Angeles CA, US
Keith Oberg - Valencia CA, US
Wayman Wendell Cheatham - Columbia MD, US
Cohava Gelber - Manassas VA, US
Assignee:
MANNKIND CORPORATION - Valencia CA
International Classification:
A61K 9/14
A61K 38/16
A61P 3/10
A61P 3/04
A61P 35/00
US Classification:
424489, 514 12
Abstract:
A composition is disclosed comprising glucagon-like peptide 1 (GLP-1) particles in combination with diketopiperazine (DKP) that is stable both in vitro and in vivo. The composition has utility as a pharmaceutical formulation for treating diseases such as diabetes, cancers, and obesity but is not limited to such diseases or conditions. In particularly, the composition has utility as a pharmaceutical formulation for pulmonary delivery.

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