Kenneth Phares resumes & CV records
Resumes
Kenneth T Phares Deceased6608 Dodge St, Mesa, AZ 85205
Kenneth Phares Phones & Addresses
6608 Dodge St, Mesa, AZ 85205
Chicago, IL
Conshohocken, PA
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Publications & IP owners
Us Patents
Combinatorial Library Approach To Iminocyclitols With Biological Activity
US Patent:
8445670, May 21, 2013
Filed:
Mar 17, 2009
Appl. No.:
12/382460
Inventors:
Robert M. Moriarty - Chicago IL, US
Carmen Mitan - Bucuresti, RO
Kenneth R. Phares - Chapel Hill NC, US
Carmen Mitan - Bucuresti, RO
Kenneth R. Phares - Chapel Hill NC, US
Assignee:
United Therapeutics Corporation - Silver Spring MD
International Classification:
C08B 37/00
C07H 5/04
C07H 5/06
C07H 5/04
C07H 5/06
US Classification:
536 553
Abstract:
A method of synthesizing stereochemically defined iminocyclitol comprises replacing an intraring oxygen in a cyclic sugar by an intraring imine to form an iminocyclitol, wherein said iminocyclitol has a defined stereochemical configuration different from a stereochemical configuration of the cyclic sugar. The invention also provides combinatorial libraries of iminocyclitol compounds, allowing for diverse C1 and N-substitution. In addition, provided are methods of treating viral infections with iminocyclitols compounds.
Combinatorial Library Approach To Iminocyclitols With Biological Activity
US Patent:
2007008, Apr 19, 2007
Filed:
Sep 1, 2006
Appl. No.:
11/514339
Inventors:
Robert Moriarity - Chicago IL, US
Carmen Mitan - Bucuresti, RO
Kenneth Phares - Chapel Hill NC, US
Carmen Mitan - Bucuresti, RO
Kenneth Phares - Chapel Hill NC, US
International Classification:
C07D 211/00
C07D 295/00
C07D 295/00
US Classification:
546184000
Abstract:
A method of synthesizing stereochemically defined iminocyclitol comprises replacing an intraring oxygen in a cyclic sugar by an intraring imine to form an iminocyclitol, wherein said iminocyclitol has a defined stereochemical configuration different from a stereochemical configuration of the cyclic sugar. The invention also provides combinatorial libraries of iminocyclitol compounds, allowing for diverse C1 and N-substitution. In addition, provided are methods of treating viral infections with iminocyclitols compounds.
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