Kirk T Lentz, 63Normal, IL
Kirk Lentz Phones & Addresses
Normal, IL
Waukegan, IL
Mentions for Kirk T Lentz
Publications & IP owners
Us Patents
Pyrrolo[3,2-B]Pyridinylalkyl Benzamide Derivatives
US Patent:
5360907, Nov 1, 1994
Filed:
Jun 14, 1993
Appl. No.:
8/077598
Inventors:
Kirk T. Lentz - Niles IL
Richard M. Weier - Lake Bluff IL
Richard M. Weier - Lake Bluff IL
Assignee:
G.D. Searle & Co. - Chicago IL
International Classification:
C07D47102
C07D47106
C07D47106
US Classification:
546113
Abstract:
The present invention relates to compounds of the formula ##STR1## wherein HET is either ##STR2## and pharmaceutical compositions containing a therapeutically effective amount of the compounds in combination with a pharmaceutically acceptable carrier and a method for treating diseases mediated by platelet activating factor.
Substituted-Phenyl (N,N'-Cycloalkyl/Alkyl Carboxamide)-1H/3H-Imidazo[4,5-B]Pyridine Compounds As Paf Antagonists
US Patent:
5359073, Oct 25, 1994
Filed:
Nov 24, 1992
Appl. No.:
7/981957
Inventors:
Richard M. Weier - Lake Bluff IL
Ish K. Khanna - Vernon Hills IL
Michael A. Stealey - Libertyville IL
Janet A. Julien - Glenview IL
Kirk T. Lentz - Niles IL
Ish K. Khanna - Vernon Hills IL
Michael A. Stealey - Libertyville IL
Janet A. Julien - Glenview IL
Kirk T. Lentz - Niles IL
Assignee:
G. D. Searle & Co. - Chicago IL
International Classification:
C07D47104
C07D47106
C07D47106
US Classification:
546118
Abstract:
A class of N,N'-cycloalkyl/alkyl benzamides of certain 1H-imidazo[4,5-b]pyridine and 3H-imidazo[4,5-b]pyridine compounds is described for treating cardiovascular and immuno-inflammatory related disorders mediated by platelet activating factor (PAF). Compounds of particular interest are those of the formula: ##STR1## wherein each of X. sup. a and X. sup. b is independently selected from nitrogen atom and --CH--, with the proviso that when one of X. sup. a and X. sup. b is selected as nitrogen atom, then the other of X. sup. a and X. sup. b must be --CH--; wherein R. sup. 1 is selected from hydrido, alkyl, hydroxyalkyl, alkoxyalkyl, phenyl, halophenyl, alkylsilyloxyalkyl, amino, monoalkylamino, dialkylamino, aminoalkyl, monoalkylaminoalkyl and dialkylaminoalkyl; wherein each of R. sup. 5, R. sup. 6, R. sup. 7 and R. sup. 8 is independently selected from hydrido, hydroxy, alkyl, alkoxy, fluoro, chloro, bromo, haloalkyl, alkylthio, alkoxyalkyl, hydroxyalkyl, alkylthioalkyl, cyano, amino, monoalkylamino and dialkylamino; wherein each of R. sup. 9 and R. sup. 10 is independently selected from hydrido, alkyl, cycloalkyl, bicycloalkyl, heteroaryl, aryl, alkenyl and cycloalkenyl, and wherein any of said R. sup. 9 and R. sup.
5-Substituted Imidazo[4,5-C]Pyridines
US Patent:
5302601, Apr 12, 1994
Filed:
Nov 6, 1992
Appl. No.:
7/973127
Inventors:
Ish K. Khannal - Vernon Hills IL
Roger Nosal - Buffalo Grove IL
Richard M. Weier - Lake Bluff IL
Kirk T. Lentz - Niles IL
Roger Nosal - Buffalo Grove IL
Richard M. Weier - Lake Bluff IL
Kirk T. Lentz - Niles IL
Assignee:
G. D. Searle & Co. - Chicago IL
International Classification:
A61K 31395
C07D47104
C07D47104
US Classification:
514303
Abstract:
The present invention relates to a class of compounds represented by the formula ##STR1## or a pharmaceutically acceptable salt thereof useful in the treatment of diseases or disorders mediated by platelet activating factor (PAF).
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