Kishore R Shah, 81568 Cabot Hill Rd, Bridgewater, NJ 08807

8257719, Sep 4, 2012

Mar 6, 2008

12/043743

Kishore R. Shah - Bridgewater NJ, US
Raynold M. Petrocelli - Grand Rapids MI, US
Jeffrey J. Fisher - Ada MI, US

Ranir, LLC - Grand Rapids MI

A61K 8/02
A61Q 11/00

424401, 424 53

An oral care composition including a hydrophilic, aliphatic, polyether-based thermoplastic polyurethane, a glycol polymer, and a poly(N-vinyl lactam). These components form a tacky film having a thickness of about 1 mils to about 50 mils. A whitening agent, such as a peroxide, can be absorbed into the tacky film, and adapted to desorb from the tacky film to whiten teeth to which the film is joined. A method is also provided in which the components are extruded through a twin screw extruder and output to a die to produce the film. The whitening agent can be deposited on the film and absorbed by the film to form a relatively stable oral care composition including the whitening agent.

2004014, Jul 22, 2004

Dec 27, 2003

10/748625

Kishore Shah - Bridgewater NJ, US

A61K009/00
A61K047/30

514/772300, 424/400000

A composition and method for treating mammalian skin by the application of a film-forming composition which is hydrophilic, but water insoluble; said film moisturizing said mammalian skin, providing increased skin retentivity of cosmetic ingredients, and providing sustained release of biologically active agents contained in the composition.

2012015, Jun 21, 2012

Dec 15, 2011

13/327180

Kishore R. SHAH - Bridgewater NJ, US

Polytherapeutics, Inc. - Bridgewater NJ

A61K 31/196
A61P 25/00
A61P 29/00

514567

This invention pertains to compositions and method for transdermal administration of non-steroidal anti-inflammatory and analgesic drugs (NSAID) for the treatment of inflammation and pain caused by conditions such as arthritis, degenerative joint disease, minor strains, pains, and contusions. This invention particularly relates to transdermal compositions comprising an NSAID, a bioadhesive graft copolymer, and a skin penetration enhancer, selected from pyrrolidone or its derivatives and dialkyl sulfoxides and combinations thereof.

5827525, Oct 27, 1998

Sep 10, 1996

8/711754

Wei-Chi Liao - Princetion Junction NJ
Agis Kydonieus - Kendall Park NJ
Kishore R. Shah - Bridgewater NJ

Bristol-Myers Squibb Company - Princeton NJ

A61F 1300

424435

A unidirectional buccal delivery system for the delivery of therapeutic agents over an extended period of time. The delivery system includes a matrix for releasing the drug into the oral cavity at a sustained rate and a means for securing the matrix to the palate or other adequate regions in the oral cavity.

4370380, Jan 25, 1983

Apr 12, 1982

6/367256

Kishore R. Shah - Chelmsford MA

The Kendall Company - Boston MA

C09J 702
C08L 3500
C08L 3906

428355

An optically clear blend of (1) a water-soluble polymer of a vinyl lactam having the structure ##STR1## in which X represents an alkylene bridge having three to five carbon atoms or a copolymer thereof with 1 to 80 mole percent of a copolymerizable monomer containing a polymerizable ethylenic unsaturation; and (2) a tacky water-insoluble copolymer of (A) an ester or a mixture of esters having the structure ##STR2## in which R' represents hydrogen or methyl and R. sub. 1 represents alkyl having from 1 to 14 carbon atoms and (B) from 1 to 12% by weight, based on the copolymer, of an ethylenic monomer containing an acid group, the vinyl lactam polymer or copolymer being present in an amount from 1 to 30% by weight of the blend and having a glass transition temperature from 20. degree. to 150. degree. C. , and the tacky copolymer having a glass transition temperature below 0. degree. C. and being present in an amount from 70 to 99% by weight of the blend and having a viscosity less than 50,000 cp at 350. degree. F.

4337325, Jun 29, 1982

Apr 4, 1980

6/137297

Kishore R. Shah - Chelmsford MA

The Kendall Company - Boston MA

C08L 3500
C08L 3906

525205

An optically clear blend of (1) a water-soluble polymer of a vinyl lactam having the structure ##STR1## in which X represents an alkylene bridge having three to five carbon atoms or a copolymer thereof with 1 to 80 mole percent of a copolymerizable monomer containing a polymerizable ethylenic unsaturation; and (2) a tacky water-insoluble copolymer of (A) an ester or a mixture of esters having the structure ##STR2## in which R' represents hydrogen or methyl and R. sub. 1 represents alkyl having from 1 to 14 carbon atoms and (B) from 1 to 12% by weight, based on the copolymer, of an ethylenic monomer containing an acid group, the vinyl lactam polymer or copolymer being present in an amount from 1 to 30% by weight of the blend and having a glass transition temperature from 20. degree. to 150. degree. C. , and the tacky copolymer having a glass transition temperature below 0. degree. C. and being present in an amount from 70 to 99% by weight of the blend and having a viscosity less than 50,000 cp at 350. degree. F.

5591820, Jan 7, 1997

May 9, 1995

8/437069

Agis Kydonieus - Kendall Park NJ
Ladislav Bastar - North Brunswick NJ
Kishore Shah - Bridgewater NJ
Khosrow Jamshidi - Princeton NJ
Sheng-hung Kuo - Princeton NJ

E. R. Squibb & Sons, Inc. - Princeton NJ

C08G 1830

528 76

Pressure-sensitive adhesives which possess absorptivity and/or permeability properties to remove transepidermal water loss and/or other bodily fluids that come into contact with the adhesive, in combination with a fine balance of cohesion and adhesion properties, can be formulated by controlling the crosslinking of a polyurethane polymer having excess hydroxyl functionality, a glass transition temperature of less than about 0. degree. C. , a moisture absorption of at least about 20% of its weight and/or a moisture vapor transmission rate of at least about 300 grams/meter. sup. 2 /24 hours measured at 37. degree. C. and a 90% relative humidity gradient. Adhesives of these polymers possess a peel adhesion to human skin of between about 0. 3 and 4 newtons/cm width of the polymer or adhesive.

4767808, Aug 30, 1988

Nov 19, 1987

7/122862

Agis Kydonieus - Kendall Park NJ
Kishore R. Shah - Bridgewater NJ
Bret Berner - Ardsley on Hudson NY

Hercon Laboratories Corporation - S. Plainfield NJ

C08J 534

524 98

Described is an article of manufacture useful for administration of pharmacologically-active substances, transdermally, orally or by means of subdermal implant comprising a solid vinyl plastisol layer for contacting a patient's tissue, internally or externally, the layer containing from about 20 up to about 70% by weight of a polyvinyl chloride resin or a polyvinyl chloride-polyvinyl acetate copolymer containing a minor proportion of vinyl acetate; from about 20-70% plasticizer composition; from about 0. 5 up to 35% of a pharmacologically-active substance such as isosorbide dinitrate, nicotine, clonidine, guanfacine, indomethacin, glyceryl trinitrate and prostaglandin and optionally excipients. Also described is the novel plasticizer-polyvinyl chloride composition of matter comprising 1-dodecylhexahydro-2H-azepin-2-one and polyvinyl chloride resin taken together with a pharmacologically-active substance wherein the 1-dodecylhexahydro-2H-azepin-2-one not only acts as a plasticizer but also acts as a penetration enhancer (through tissue) for the pharmacologically-active substance.