Lejla Pilipovic resumes & CV records
Resumes
Scientist, Oncology
Location:
Greater Boston Area
Industry:
Pharmaceuticals
Lejla P Pilipovic, 53Somerville, MA
Lejla Pilipovic Phones & Addresses
Somerville, MA
Allston, MA
Arlington, MA
Medford, MA
Malden, MA
Andover, MA
Mentions for Lejla P Pilipovic
Publications & IP owners
Us Patents
Identification Of Multigene Biomarkers
US Patent:
2013016, Jun 27, 2013
Filed:
Nov 5, 2012
Appl. No.:
13/669275
Inventors:
AVEO PHARMACEUTICALS, INC. - Cambridge MA, US
Bin Feng - North Reading MA, US
Richard Nicoletti - Southborough MA, US
Joshua P. Frederick - Boston MA, US
Lejla Pilipovic - Somerville MA, US
Bin Feng - North Reading MA, US
Richard Nicoletti - Southborough MA, US
Joshua P. Frederick - Boston MA, US
Lejla Pilipovic - Somerville MA, US
Assignee:
AVEO PHARMACEUTICALS, INC. - Cambridge MA
International Classification:
C40B 30/04
C40B 40/06
C40B 40/06
US Classification:
506 9, 506 16, 702 19
Abstract:
Methods for identifying multigene biomarkers for predicting sensitivity or resistance to an anti-cancer drug of interest, or multigene cancer prognostic biomarkers are disclosed. The disclosed methods are based on the classification of the mammalian genome into 51 transcription clusters, i.e., non-overlapping, functionally relevant groups of genes whose intra-group transcript levels are highly correlated. Also disclosed are specific multigene biomarkers for predicting sensitivity or resistance to tivozanib, or rapamycin, and a specific multigene biomarker for determining breast cancer prognosis, all of which were identified using the methods disclosed herein.
Identification Of Multigene Biomarkers
US Patent:
2013016, Jun 27, 2013
Filed:
Feb 25, 2013
Appl. No.:
13/775928
Inventors:
AVEO Pharmaceuticals, Inc. - Cambridge MA, US
Bin Feng - Newton MA, US
Richard Nicoletti - Southborough MA, US
Joshua P. Frederick - Boston MA, US
Lejla Pilipovic - Somerville MA, US
Bin Feng - Newton MA, US
Richard Nicoletti - Southborough MA, US
Joshua P. Frederick - Boston MA, US
Lejla Pilipovic - Somerville MA, US
Assignee:
AVEO Pharmaceuticals, Inc. - Cambridge MA
International Classification:
C12Q 1/68
US Classification:
506 9, 435 612, 702 19
Abstract:
Methods for identifying multigene biomarkers for predicting sensitivity or resistance to an anti-cancer drug of interest, or multigene cancer prognostic biomarkers are disclosed. The disclosed methods are based on the classification of the mammalian genome into 51 transcription clusters, i.e., non-overlapping, functionally relevant groups of genes whose intra-group transcript levels are highly correlated. Also disclosed are specific multigene biomarkers for predicting sensitivity or resistance to tivozanib, or rapamycin, and a specific multigene biomarker for determining breast cancer prognosis, all of which were identified using the methods disclosed herein.
Possible Relatives
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