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Lisha D Allen, 35Sacramento, CA

Known as:
Lisha Danielle Allen
Related to:
Kelly A Thurmond 38

Lisha Allen Phones & Addresses

Sacramento, CA   

1202 Theresa Way, Yuba City, CA 95993   

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Lisha Allen

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Us Patents

Homogenous Antibody Drug Conjugates Via Enzymatic Methods

US Patent:
2018036, Dec 20, 2018
Filed:
May 22, 2018
Appl. No.:
15/986665
Inventors:
- Sacramento CA, US
Lisha ALLEN - Sacramento CA, US
International Classification:
A61K 31/255
C07K 16/28
C07K 16/32
A61K 47/68
C12N 9/10
C07K 16/30
Abstract:
The present application in one aspect provide Fc-containing polypeptide conjugates comprising an Fc-containing polypeptide conjugated to a conjugate moiety, wherein the Fc-containing polypeptide comprises an N-glycosylated Fc region comprising an acceptor glutamine residue flanked by an N-glycosylation site and wherein the conjugate moiety is conjugated to the Fc-containing polypeptide via the acceptor glutamine residue. Also provided are methods of making such Fc-containing polypeptide conjugates by using a wildtype or engineered transglutaminases. Further provided are engineered transglutaminases specifically designed for carrying out such reactions.

Homogenous Antibody Drug Conjugates Via Enzymatic Methods

US Patent:
2018036, Dec 20, 2018
Filed:
May 22, 2018
Appl. No.:
15/986668
Inventors:
- Sacramento CA, US
Lisha Allen - Sacramento CA, US
International Classification:
A61K 31/255
C07K 16/28
C07K 16/32
A61K 47/68
C12N 9/10
C07K 16/30
Abstract:
The present application in one aspect provide Fc-containing polypeptide conjugates comprising an Fc-containing polypeptide conjugated to a conjugate moiety, wherein the Fc-containing polypeptide comprises an N-glycosylated Fc region comprising an acceptor glutamine residue flanked by an N-glycosylation site and wherein the conjugate moiety is conjugated to the Fc-containing polypeptide via the acceptor glutamine residue. Also provided are methods of making such Fc-containing polypeptide conjugates by using a wildtype or engineered transglutaminases. Further provided are engineered transglutaminases specifically designed for carrying out such reactions.

Homogenous Antibody Drug Conjugates Via Enzymatic Methods

US Patent:
2017010, Apr 20, 2017
Filed:
Jun 11, 2015
Appl. No.:
15/317907
Inventors:
- Sacramento CA, US
Lisha ALLEN - Sacramento CA, US
International Classification:
C07K 16/00
C07K 16/28
C12N 9/10
A61K 31/255
Abstract:
The present application in one aspect provide Fc-containing polypeptide conjugates comprising an Fc-containing polypeptide conjugated to a conjugate moiety, wherein the Fc-containing polypeptide comprises an N-glycosylated Fc region comprising an acceptor glutamine residue flanked by an N-glycosylation site and wherein the conjugate moiety is conjugated to the Fc-containing polypeptide via the acceptor glutamine residue. Also provided are methods of making such Fc-containing polypeptide conjugates by using a wildtype or engineered transglutaminases. Further provided are engineered transglutaminases specifically designed for carrying out such reactions.

Possible Relatives

Cynthia M Allen  David A Allen  Cyril J Allen  Davida N Allen  Davie C Allen  Davone L Allen  Dawn Allen  Lisha J Kerr  Lisha A Lambert  Lisha M Lewis 

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