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Liv E Jensen, 35Oakland, CA

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Emeryville, CA   

Berkeley, CA   

2140 Dartmouth St, Palo Alto, CA 94306    650-4930322   

Redwood City, CA   

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Liv Jensen

Liv Jensen was a Norwegian luger who competed in the late 1930s. She won a silver medal in the women's singles event at the 1937 European luge ...

Us Patents

Alpha-Hemolysin Variants

US Patent:
2020032, Oct 15, 2020
Filed:
Jun 30, 2020
Appl. No.:
16/917435
Inventors:
- Pleasanton CA, US
Cynthia Ann CECH - Newcastle WA, US
Michael DORWART - Mountain View CA, US
Liv Elisabeth JENSEN - Palo Alto CA, US
Marshall Winston PORTER - Santa Clara CA, US
Alexander Hyun-min YANG - Campbell CA, US
Assignee:
Roche Sequencing Solutions, Inc. - Pleasanton CA
International Classification:
C12Q 1/6869
C07K 14/31
Abstract:
Described herein are engineered alpha-hemolysin subunits having mutated oligomerization domains for assembling into heptameric nanopores in lipid bilayers.

Nanopore Sequencing Complexes

US Patent:
2020021, Jul 9, 2020
Filed:
Jan 20, 2017
Appl. No.:
16/071406
Inventors:
- Santa Clara CA, US
- Mannheim, DE
Alexander H. Yang - Campbell CA, US
Liv E. Jensen - Palo Alto CA, US
Marshall Porter - Santa Clara CA, US
Charlotte Yang - San Jose CA, US
Corissa Harris - Santa Clara CA, US
Matt Dipetro - Gilroy CA, US
Assignee:
Genia Technologies, Inc. - Santa Clara CA
International Classification:
C12Q 1/6869
C12N 9/12
Abstract:
A method is provided for preparing nanopore sequencing complexes in membranes for sequencing of polymers, e.g., polynucleotides and polypeptides. The nanopore sequencing complex is formed by the sequential linking of an enzyme to a nanopore that is inserted in a membrane, and of a polymer to the enzyme. Alternatively, the nanopore sequencing complex is formed by linking a preformed enzyme-polymer complex to a nanopore that is inserted in a membrane. The enzyme polymer complex is interchangeable.

Ompg Variants

US Patent:
2018036, Dec 20, 2018
Filed:
Sep 20, 2016
Appl. No.:
15/762092
Inventors:
- Santa Clara CA, US
Tim CRAIG - Mountain View CA, US
Alexander YANG - Mountain View CA, US
Liv JENSEN - Mountain View CA, US
Charlotte YANG - Mountain View CA, US
Corissa HARRIS - Mountain View CA, US
Assignee:
GENIA TECHNOLOGIES, INC. - Santa Clara CA
International Classification:
C07K 14/245
C12N 9/12
C12Q 1/6874
Abstract:
The present disclosure provides variant OmpG polypeptides, compositions comprising the OmpG variant polypeptides, and methods for using the variant OmpG polypeptides as nanopores for determining the sequence of single stranded nucleic acids. The variant OmpG nanopores reduce the ionic current noise versus the parental OmpG polypeptide from which they are derived and thereby enable sequencing of polynucleotides with single nucleotide resolution. The reduced ionic current noise also provides for the use of these OmpG nanopore variants in other single molecule sensing applications, e.g., protein sequencing.

Alpha-Hemolysin Variants

US Patent:
2017008, Mar 30, 2017
Filed:
Sep 23, 2016
Appl. No.:
15/274770
Inventors:
- Santa Clara CA, US
Cynthia Ann CECH - Newcastle WA, US
Michael DORWART - Mtn. View CA, US
Liv Elisabeth JENSEN - Palo Alto CA, US
Marshall Winston PORTER - Santa Clara CA, US
Alexander Hyun-min YANG - Campbell CA, US
International Classification:
C12Q 1/68
C07K 14/31
Abstract:
Described herein are engineered alpha-hemolysin subunits having mutated oligomerization domains for assembling into heptameric nanopores in lipid bilayers.

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