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Lloyd M Greene, 77Bayshore, NY

Lloyd Greene Phones & Addresses

Bay Shore, NY   

Little Neck, NY   

Woodbury, NJ   

West Islip, NY   

PO Box 5298, Bay Shore, NY 11706   

Work

Position: Precision Production Occupations

Education

Degree: Associate degree or higher

Emails

Mentions for Lloyd M Greene

Career records & work history

Medicine Doctors

Lloyd H. Greene

Specialties:
Cardiovascular Disease
Work:
University Hospital Medical PhysiciansUniversity Hospital Case Medical Center Cardiology
11100 Euclid Ave Mather Pavilion 1800, Cleveland, OH 44106
216-8443800 (phone) 216-8448954 (fax)
Site
Education:
Medical School
New York University School of Medicine
Graduated: 1987
Languages:
English
Description:
Dr. Greene graduated from the New York University School of Medicine in 1987. He works in Cleveland, OH and specializes in Cardiovascular Disease. Dr. Greene is affiliated with University Hospitals Cleveland Medical Center.

Lloyd Greene resumes & CV records

Resumes

Lloyd Greene Photo 29

Director Of Sales At At&T Corp

Location:
Greater New York City Area
Industry:
Telecommunications
Lloyd Greene Photo 30

Lloyd Greene

Lloyd Greene Photo 31

Lloyd Greene

Lloyd Greene Photo 32

Lloyd Greene

Publications & IP owners

Us Patents

Methods For Promoting Apoptosis And Treating Tumor Cells Inhibiting The Expression Or Function Of The Transcription Factor Atf5

US Patent:
7888326, Feb 15, 2011
Filed:
Apr 3, 2008
Appl. No.:
12/062178
Inventors:
Lloyd A Greene - Larchmont NY, US
James M Angelastro - Davis CA, US
Assignee:
The Trustees of Columbia University in the City of New York - New York NY
International Classification:
A61K 48/00
A61K 39/395
A01N 63/00
A01N 65/00
US Classification:
514 44R, 424 931, 4241301
Abstract:
The present invention provides methods for regulating the growth and/or survival of tumor cells and stem cells by modulating the expression or function of ATF5. The present invention also provides methods for promoting or suppressing differentiation of stem/progenitor cells, for producing differentiated cells and for isolating/purifying differentiated cells, including neural cells. Also provided are differentiated cells, cell populations and transgenic animals comprising same and uses of same. The present invention further provides methods for treating nervous tissue degeneration and for identifying an agent for use in treating nervous tissue degeneration. Methods for promoting apoptosis in neoplastic cells and for treating or preventing tumors, and identifying agents for use in treating or preventing tumors are also provided by the present invention. The present invention further provides methods for identifying agents that inhibit ATF5, agents identified by these methods. Also provided are methods for diagnosing tumors, for assessing the efficacy of therapy to treat tumors and for assessing the prognosis of a subject who has a neural tumor.

Methods For Inhibiting The Differentation Of Proliferative Telencephalic Cells In Vitro By Addition Of Atf5

US Patent:
8158420, Apr 17, 2012
Filed:
Oct 22, 2004
Appl. No.:
10/971483
Inventors:
Lloyd A Greene - Larchmont NY, US
James M Angelastro - Davis CA, US
Assignee:
The Trustees of Columbia University in the City of New York - New York NY
International Classification:
C12N 5/02
C12N 5/04
C12N 5/00
G03C 5/16
US Classification:
435376, 435325, 435377, 430350
Abstract:
The present invention provides methods for regulating the growth and/or survival of tumor cells and stem cells by modulating the expression or function of ATF5. The present invention also provides methods for promoting or suppressing differentiation of stem/progenitor cells, for producing differentiated cells and for isolating/purifying differentiated cells, including neural cells. Also provided are differentiated cells, cell populations and transgenic animals comprising same and uses of same. The present invention further provides methods for treating nervous tissue degeneration and for identifying an agent for use in treating nervous tissue degeneration. Methods for promoting apoptosis in neoplastic cells and for treating or preventing tumors, and identifying agents for use in treating or preventing tumors are also provided by the present invention. The present invention further provides methods for identifying agents that inhibit ATF5, agents identified by these methods. Also provided are methods for diagnosing tumors, for assessing the efficacy of therapy to treat tumors and for assessing the prognosis of a subject who has a neural tumor.

Complex For Facilitating Delivery Of Dsrna Into A Cell And Uses Thereof

US Patent:
2004014, Jul 29, 2004
Filed:
Jan 28, 2003
Appl. No.:
10/353902
Inventors:
Carol Troy - Hastings-on-Hudson NY, US
Lloyd Greene - Larchmont NY, US
International Classification:
A61K048/00
C12N015/88
US Classification:
435/458000, 514/044000
Abstract:
The present invention provides a membrane-permeable complex for facilitating the delivery of a double-stranded ribonucleic acid molecule into a cell. Specifically, the invention provides a membrane-permeable complex that comprises a double-stranded ribonucleic acid molecule, such as a small interfering RNA, a cell-penetrating peptide, and a covalent bond linking the double-stranded ribonucleic acid to the cell-penetrating peptide. Also provided are methods of using the membrane-permeable complex of the present invention to deliver the double-stranded ribonucleic acid molecule to a cell or to inhibit expression of a gene product by a cell.

Dopaminergic Cell Lines Stably Expressing A53T Alpha-Synuclein And Methods Of Using Same

US Patent:
2004019, Oct 7, 2004
Filed:
Dec 15, 2003
Appl. No.:
10/737262
Inventors:
Leonidas Stefanis - Ilisia, GR
Lloyd Greene - Larchmont NY, US
International Classification:
A61K048/00
C12N005/06
C12N015/85
US Classification:
424/093210, 435/455000, 435/353000
Abstract:
The present invention discloses a PC12 cell line stably expressing human A53T -synuclein, wherein a cell of the cell line is characterized by proteasomal dysfunction, dopaminergic dysfunction, lysosomal dysfunction, and increased non-apoptotic cell death, as compared to cells of suitable control cell line not expressing mutant -synuclein. Also provided are methods of making the cells of the present invention. The unique phenotype associated with the cells described herein provide a cellular model for the study of Parkinson's Disease, as well as for other synucleinopathic neurodegenerative disorders, including, but not limited to, Dementia with Lewy Bodies, Lewy Body Variant of Alzheimer's Disease, Multiple System Atrophy and Hallervorden-Spatz syndrome.

Methods For Regulating Differentiation Of Neural Cells And Uses Thereof

US Patent:
2005016, Jul 28, 2005
Filed:
Mar 24, 2004
Appl. No.:
10/809312
Inventors:
Lloyd Greene - Larchmont NY, US
James Angelastro - Davis CA, US
International Classification:
C12N005/08
US Classification:
435368000
Abstract:
The present invention provides methods for promoting or suppressing differentiation of neural stem/progenitor cells, for producing differentiated neural cells, and for isolating/purifying differentiated neural cells. Also provided are differentiated neural cells, cell populations and transgenic animals comprising same, and uses of same. The present invention further provides methods for treating nervous tissue degeneration, and for identifying an agent for use in treating nervous tissue degeneration. Additionally, the present invention provides a therapeutic composition, and methods for treating neural tumors using same. The present invention further provides methods for identifying agents which inhibit ATF5, agents identified by these methods, and uses of same. Also provided are methods for diagnosing neural tumors, for assessing the efficacy of therapy to treat neural tumors, and for assessing the prognosis of a subject who has a neural tumor. Finally, the present invention provides a kit for use in detecting a neural tumor.

Complex For Facilitating Delivery Of Dsrna Into A Cell And Uses Thereof

US Patent:
2005026, Nov 24, 2005
Filed:
Feb 25, 2005
Appl. No.:
11/067092
Inventors:
Carol Troy - Hastings-on-Hudson NY, US
Lloyd Greene - Larchmont NY, US
International Classification:
C12N015/88
US Classification:
435458000
Abstract:
The present invention provides a membrane-permeable complex for facilitating the delivery of a double-stranded ribonucleic acid molecule into a cell. Specifically, the invention provides a membrane-permeable complex that comprises a double-stranded ribonucleic acid molecule, such as a small interfering RNA, a cell-penetrating peptide, and a covalent bond linking the double-stranded ribonucleic acid to the cell-penetrating peptide. Also provided are methods of using the membrane-permeable complex of the present invention to deliver the double-stranded ribonucleic acid molecule to a cell or to inhibit expression of a gene product by a cell.

Systems And Methods For Silencing Expression Of A Gene In A Cell And Uses Thereof

US Patent:
2006017, Aug 10, 2006
Filed:
May 23, 2005
Appl. No.:
11/136344
Inventors:
Carol Troy - Hastings-on-Hudson NY, US
Lloyd Greene - Larchmont NY, US
International Classification:
A61K 48/00
C12N 5/08
C12N 15/87
US Classification:
514007000, 514044000, 435455000, 435368000
Abstract:
The present invention provides RNA-based systems that are capable of silencing expression of a gene in a cell. Also provided are pharmaceutical compositions, cells, and kits that include the systems; cultures of primary cells that have been contacted with the systems; use of the systems in methods of studying protein function in one or more cells; and use of the systems in methods of studying interactions between neurons in culture; and use of the systems in a method of studying the function of mRNA. The present invention further provides methods for silencing expression of a gene in a cell, and methods for determining the function of a gene in a cell. Additionally, the present invention provides systems for use in genetic screening, and methods for performing genetic screening.

Methods For Regulating Differentiation Of Neural Cells And Uses Thereof

US Patent:
2007009, Apr 26, 2007
Filed:
Sep 20, 2006
Appl. No.:
11/524162
Inventors:
Lloyd Greene - Larchmont NY, US
James Angelastro - Davis CA, US
International Classification:
A61K 35/30
C12N 5/08
US Classification:
424093700, 435368000
Abstract:
The present invention provides methods for promoting or suppressing differentiation of neural stem/progenitor cells, for producing differentiated neural cells, and for isolating/purifying differentiated neural cells. Also provided are differentiated neural cells, cell populations and transgenic animals comprising same, and uses of same. The present invention further provides methods for treating nervous tissue degeneration, and for identifying an agent for use in treating nervous tissue degeneration. Additionally, the present invention provides a therapeutic composition, and methods for treating neural tumors using same. The present invention further provides methods for identifying agents which inhibit ATF5, agents identified by these methods, and uses of same. Also provided are methods for diagnosing neural tumors, for assessing the efficacy of therapy to treat neural tumors, and for assessing the prognosis of a subject who has a neural tumor. Finally, the present invention provides a kit for use in detecting a neural tumor.

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