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Lucian V Dipietro, 43Nashua, NH

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Nashua, NH   

Cashtown, PA   

Gloucester, MA   

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Us Patents

Substituted Alkylamine Derivatives And Methods Of Use

US Patent:
6878714, Apr 12, 2005
Filed:
Jul 17, 2002
Appl. No.:
10/197974
Inventors:
Benny Askew - Newbury Park CA, US
Jeffrey Adams - Thousand Oaks CA, US
Shon Booker - Thousand Oaks CA, US
Guoqing Chen - Thousand Oaks CA, US
Lucian V. DiPietro - Gloucester MA, US
Daniel Elbaum - Newton MA, US
Julie Germain - Medford MA, US
Stephanie D. Geuns-Meyer - Medford MA, US
Gregory J. Habgood - Merrimac MA, US
Michael Handley - Greenbrae CA, US
Qi Huang - Moorpark CA, US
Aiwen Li - Westlake Village CA, US
Nobuko Nishimura - West Hills CA, US
Rana Nomak - Istanbul, TR
Vinod F. Patel - Acton MA, US
Babak Riahi - Woodland Hills CA, US
Joseph L. Kim - Wayland MA, US
Ning Xi - Thousand Oaks CA, US
Kevin Yang - San Gabriel CA, US
Chester Chenguang Yuan - Newbury Park CA, US
Assignee:
Amgen Inc. - Thousand Oaks CA
International Classification:
A61K031/4427
C07D401/12
US Classification:
514256, 514300, 514314, 514333, 514336, 514337, 544333, 546113, 546175, 546256, 546262, 5462717, 5462821, 5462827
Abstract:
Selected amines are effective for prophylaxis and treatment of diseases, such as angiogenesis mediated diseases. The invention encompasses novel compounds, analogs, prodrugs and pharmaceutically acceptable salts thereof, pharmaceutical compositions and methods for prophylaxis and treatment of diseases and other maladies or conditions involving, cancer and the like. The subject invention also relates to processes for making such compounds as well as to intermediates useful in such processes.

Kinase Inhibitors

US Patent:
7074789, Jul 11, 2006
Filed:
Oct 31, 2003
Appl. No.:
10/699518
Inventors:
David M. Armistead - Sudbury MA, US
Jean E. Bemis - Arlington MA, US
John L. Buchanan - Brookline MA, US
Lucian V. DiPietro - Gloucester MA, US
Daniel Elbaum - Newton MA, US
Stephanie D. Geuns-Meyer - Medford MA, US
Gregory J. Habgood - Merrimack MA, US
Joseph L. Kim - Wayland MA, US
Teresa L. Marshall - Stow MA, US
Perry M. Novak - Milford MA, US
Joseph J. Nunes - Andover MA, US
Vinod F. Patel - Acton MA, US
Leticia M. Toledo-Sherman - Venice CA, US
Xiaotian Zhu - Watertown MA, US
Assignee:
Amgen Inc. - Thousand Oaks CA
International Classification:
C07D 403/12
C07D 403/14
A61K 31/4155
A61P 35/04
US Classification:
514241, 544206, 544207, 544208, 544209, 544210, 544219
Abstract:
The invention relates to inhibitors of enzymes that bind to ATP or GTP and/or catalyze phosphoryl transfer, compositions comprising the inhibitors, and methods of using the inhibitors and inhibitor compositions. The inhibitors and compositions comprising them are useful for treating disease or disease symptoms. The invention also provides for methods of making phosphoryl transferase inhibitor compounds, methods of inhibiting phosphoryl transferase activity, and methods for treating disease or disease symptoms.

Substituted Amine Derivatives And Methods Of Use

US Patent:
7102009, Sep 5, 2006
Filed:
Jul 17, 2002
Appl. No.:
10/197918
Inventors:
Vinod F. Patel - Acton MA, US
Benny Askew - Newbury Park CA, US
Shon Booker - Newbury Park CA, US
Guoqing Chen - Thousand Oaks CA, US
Lucian V. DiPietro - Gloucester MA, US
Julie Germain - Somerville MA, US
Gregory J. Habgood - Merrimac MA, US
Qi Huang - Moorpark CA, US
Aiwen Li - Westlake Village CA, US
Nobuko Nishimura - West Hills CA, US
Rana Nomak - Westlake Village CA, US
Babak Riahi - Woodland Hills CA, US
Chester Chenguang Yuan - Newbury Park CA, US
Daniel Elbaum - Newton MA, US
Assignee:
Amgen Inc. - Thousand Oaks CA
International Classification:
C07D 401/02
A61K 31/44
US Classification:
5462771, 5462737, 5462757, 544253, 514255, 514338, 514339
Abstract:
Selected amines are effective for prophylaxis and treatment of diseases, such as angiogenesis mediated diseases. The invention encompasses novel compounds, analogs, prodrugs and pharmaceutically acceptable salts thereof, pharmaceutical compositions and methods for prophylaxis and treatment of diseases and other maladies or conditions involving, cancer and the like. The subject invention also relates to processes for making such compounds as well as to intermediates useful in such processes.

Kinase Inhibitors

US Patent:
7282504, Oct 16, 2007
Filed:
May 9, 2005
Appl. No.:
11/125614
Inventors:
David M. Armistead - Sudbury MA, US
Jean E Bemis - Arlington MA, US
Lucian V DiPietro - Gloucester MA, US
Stephanie D. Geuns-Meyer - Medford MA, US
Gregory J. Habgood - Merrimac MA, US
Joseph L. Kim - Wayland MA, US
Joseph J. Nunes - Andover MA, US
Vinod F. Patel - Acton MA, US
Leticia M. Toledo-Sherman - Venice CA, US
Assignee:
Amgen Inc. - Thousand Oaks CA
International Classification:
C07D 403/04
A61K 31/404
US Classification:
514275, 544122, 544323, 544324
Abstract:
The invention relates to inhibitors of kinases, compositions comprising the inhibitors, and methods of using the inhibitors and inhibitor compositions. The inhibitors and compositions comprising them are useful for treating disease or disease symptoms. The invention also provides for methods of making kinase inhibitor compounds, methods of inhibiting kinase activity, and methods for treating disease or disease symptoms.

Compounds And Methods Of Use

US Patent:
7435823, Oct 14, 2008
Filed:
Jan 24, 2005
Appl. No.:
11/042634
Inventors:
Michele Potashman - Cambridge MA, US
Steven Bellon - Wellesley MA, US
Shon Booker - Thousand Oaks CA, US
Yuan Cheng - Newbury Park CA, US
Joseph L. Kim - Wayland MA, US
Andrew Tasker - Simi Valley CA, US
Ning Xi - Thousand Oaks CA, US
Shimin Xu - Ventura CA, US
Jean-Christophe Harmange - Andover MA, US
George Borg - Cambridge MA, US
Matthew Weiss - Boston MA, US
Brian L. Hodous - Cambridge MA, US
Russell Graceffa - Hampton NH, US
William H. Buckner - Arlington MA, US
Craig E. Masse - Cambridge MA, US
Deborah Choquette - Medford MA, US
Matthew W. Martin - Cambridge MA, US
Julie Germain - Medford MA, US
Lucian V. DiPietro - Gloucester MA, US
Stuart C. Chaffee - Cambridge MA, US
Joseph J. Nunes - Andover MA, US
John L. Buchanan - Brookline MA, US
Gregory J. Habgood - Merrimac MA, US
David C. McGowan - Woluwe St. Pierre, BE
Douglas A. Whittington - Waltham MA, US
Daniel La - Brookline MA, US
Vinod F. Patel - Acton MA, US
Assignee:
Amgen Inc. - Thousand Oaks CA
International Classification:
C07D 215/38
C07D 265/34
US Classification:
546153, 546 15, 544 99, 544105
Abstract:
Selected compounds are effective for prophylaxis and treatment of diseases, such as HGF mediated diseases. The invention encompasses novel compounds, analogs, prodrugs and pharmaceutically acceptable salts thereof, pharmaceutical compositions and methods for prophylaxis and treatment of diseases and other maladies or conditions involving, cancer and the like. The subject invention also relates to processes for making such compounds as well as to intermediates useful in such processes.

Compounds And Methods Of Use

US Patent:
8178557, May 15, 2012
Filed:
Jun 9, 2008
Appl. No.:
12/157303
Inventors:
Michele Potashman - Cambridge MA, US
Steven Bellon - Wellesley MA, US
Shon Booker - Thousand Oaks CA, US
Yuan Cheng - Newbury Park CA, US
Joseph L. Kim - Wayland MA, US
Andrew Tasker - Simi Valley CA, US
Ning Xi - Thousand Oaks CA, US
Shimin Xu - San Diego CA, US
Jean-Christophe Harmange - Andover MA, US
George Borg - Somerville MA, US
Matthew Weiss - Boston MA, US
Brian L. Hodous - Cambridge MA, US
Russell Graceffa - Hampton NH, US
William H. Buckner - Kittery ME, US
Craig E. Masse - Cambridge MA, US
Deborah Choquette - Medford MA, US
Matthew W. Martin - Arlington MA, US
Julie Germain - Quebec, CA
Lucian V. DiPietro - Gloucester MA, US
Stuart C. Chaffee - Boston MA, US
Joseph J. Nunes - Andover MA, US
John L. Buchanan - Newton MA, US
David C. McGowan - Brussels, BE
Douglas A. Whittington - Waltham MA, US
Gregory J. Habgood - Merrimac MA, US
Vinod F. Patel - Acton MA, US
Daniel La - Brookline MA, US
Assignee:
Amgen Inc. - Thousand Oaks CA
International Classification:
A61K 31/04
US Classification:
514312
Abstract:
Selected compounds are effective for prophylaxis and treatment of diseases, such as HGF mediated diseases. The invention encompasses novel compounds, analogs, prodrugs and pharmaceutically acceptable salts thereof, pharmaceutical compositions and methods for prophylaxis and treatment of diseases and other maladies or conditions involving, cancer and the like. The subject invention also relates to processes for making such compounds as well as to intermediates useful in such processes.

Substituted Alkylamine Derivatives And Methods Of Use

US Patent:
8642624, Feb 4, 2014
Filed:
Nov 15, 2011
Appl. No.:
13/297213
Inventors:
Guoqing Chen - Thousand Oaks CA, US
Jeffrey A. Adams - Chagrin Falls OH, US
Jean E. Bemis - Arlington MA, US
Shon Booker - Thousand Oaks CA, US
Guolin Cai - Thousand Oaks CA, US
Lucian V. DiPietro - Gloucester MA, US
Celia Dominguez - Los Angeles CA, US
Daniel Elbaum - Newton MA, US
Julie Germain - Somerville MA, US
Stephanie Geuns-Meyer - Medford MA, US
Michael K. Handley - Greenbrae CA, US
Qi Huang - Moorpark CA, US
Joseph L. Kim - Wayland MA, US
Alexander S. Kiselyov - Jersey City NJ, US
Xiaohu Ouyang - Brooklyn NY, US
Vinod F. Patel - Acton MA, US
Leon M. Smith - Somerset NJ, US
Markian M. Stec - Moorpark CA, US
Andrew Tasker - Simi Valley CA, US
Ning Xi - Thousand Oaks CA, US
Shimin Xu - San Diego CA, US
Chester Chenguang Yuan - Newbury Park CA, US
Michael D. Croghan - Thousand Oaks CA, US
Assignee:
Amgen Inc. - Thousand Oaks CA
International Classification:
A01N 43/40
A61K 31/44
A01N 43/38
A61K 31/40
A61K 31/405
US Classification:
514333, 514352, 514355, 514415, 514277, 514414
Abstract:
Selected heterocyclic compounds are effective for prophylaxis and treatment of diseases, such as angiogenesis mediated diseases. The invention encompasses novel compounds, analogs, prodrugs and pharmaceutically acceptable derivatives thereof, pharmaceutical compositions and methods for prophylaxis and treatment of diseases and other maladies or conditions involving, cancer and the like.

Kinase Inhibitors

US Patent:
2002005, May 2, 2002
Filed:
Feb 16, 2001
Appl. No.:
09/785599
Inventors:
David Armistead - Sudbury MA, US
Jean Bemis - Arlington MA, US
Lucian DiPietro - Gloucester MA, US
Stephanie Geuns-Meyer - Medford MA, US
Gregory Habgood - Merrimac MA, US
Joseph Kim - Wayland MA, US
Joseph Nunes - Andover MA, US
Vinod Patel - Acton MA, US
Leticia Toledo-Sherman - Somerville MA, US
International Classification:
A61K031/513
A61K031/505
C07D239/02
US Classification:
514/269000, 514/272000, 544/309000, 544/323000
Abstract:
The invention relates to inhibitors of kinases, compositions comprising the inhibitors, and methods of using the inhibitors and inhibitor compositions. The inhibitors and compositions comprising them are useful for treating disease or disease symptoms. The invention also provides for methods of making kinase inhibitor compounds, methods of inhibiting kinase activity, and methods for treating disease or disease symptoms.

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