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Marc T Boudreau, 56Wells, ME

Known as:
Mac Boudreau Mark Boudrou
Related to:
David Rd Bloom 72 James E Moran 47 Wayne Wilson 69 Bryanna Wilson 26 Margaret Wilkens 70 Laurie A Marr 44 Colleen Moran 52

Marc Boudreau Phones & Addresses

Wells, ME   

Abbot, ME   

Seabrook, NH   

13 Pocahontas Dr, Peabody, MA 01960    978-5354504   

Middleton, MA   

Danvers, MA   

13 Pocahontas Dr, Peabody, MA 01960   

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Marc Boudreau resumes & CV records

Resumes

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Marc Boudreau

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Marc Boudreau

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Marc Boudreau

Location:
United States
Marc Boudreau Photo 42

Marc Boudreau

Location:
United States

Publications & IP owners

Us Patents

Potentiators Of Beta-Lactam Antibiotics

US Patent:
2018004, Feb 15, 2018
Filed:
Mar 7, 2016
Appl. No.:
15/555851
Inventors:
- South Bend IN, US
Marc A. BOUDREAU - Durham NH, US
Assignee:
UNIVERSITY OF NOTRE DAME DU LAC - South Bend IN
International Classification:
C07D 401/04
A61K 45/06
C07D 401/14
C07D 413/14
A61K 31/454
C07D 403/04
A61K 31/506
C07D 233/64
A61K 31/4164
C07D 409/04
A61K 31/4178
C07D 277/22
A61K 31/426
C07D 417/04
C07D 405/14
A61K 31/4439
Abstract:
We disclose herein that the BlaR1 protein of methicillin-resistant (MRSA), an antibiotic sensor/signal transducer, is phosphorylated on exposure to β-lactam antibiotics. This event is critical for the onset of the biochemical events that unleash induction of antibiotic resistance. The BlaR1 phosphorylation and the antibiotic-resistance phenotype are abrogated in the presence of inhibitors described herein that restore susceptibility of the organism to β-lactam antibiotics. The invention thus provides compounds and methods for abrogating antibiotic resistance to β-lactam antibiotics and for treating infections causes by antibiotics prone to developing resistance.

Possible Relatives

David E Boudreau  Dayna L Boudreau  Dean P Boudreau  Damien E Boudreau  Dan J Boudreau  Danelle K Boudreau  Debra L Boudreau  Marc R Johnson  Marc E Stander  Marc R Johnston 

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