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Marie Archer, 37Arlington, VA

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Arlington, VA   

Portland, ME   

Brentwood, NY   

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Marie Archer Photo 41

Personal Support Specialist

Location:
Portland, ME
Industry:
Health, Wellness And Fitness
Work:
Home Care For Maine
Personal Support Specialist
Skills:
Healthcare, Coaching, Wellness, Strategic Planning, Microsoft Office, Microsoft Word
Marie Archer Photo 42

Marie Archer

Marie Archer Photo 43

Research Biologist At Naval Research Laboratory

Location:
Washington D.C. Metro Area
Industry:
Defense & Space

Publications & IP owners

Us Patents

Solid Phase For Capture Of Nucleic Acids

US Patent:
2008029, Nov 27, 2008
Filed:
May 21, 2007
Appl. No.:
11/751096
Inventors:
Marie J. Archer - Alexandria VA, US
Baochuan Lin - Bethesda MD, US
David A. Stenger - Herndon VA, US
Assignee:
The Govermment of the US, as represented by the Secretary of the Navy - Washington DC
International Classification:
C40B 40/08
C40B 50/18
US Classification:
506 17, 506 32
Abstract:
A method of: providing a solid surface having a dendrimer molecule bound thereto and a single-stranded probe nucleic acid immobilized to the dendrimer; contacting the solid surface with a sample suspected or known to contain a double-stranded complimentary target nucleic acid; denaturing the target nucleic acids at thermal conditions and in a salt concentration sufficient to denature the target nucleic acids to produce denatured nucleic acids; and cooling the sample to allow hybridization of the denatured nucleic acids to the probe nucleic acids. An article having: one or more paramagnetic microbeads; a dendrimer molecule bound to the beads; and a probe nucleic acid immobilized to the dendrimer.

Method For Direct Capture Of Ribonucleic Acid

US Patent:
2010011, May 6, 2010
Filed:
Nov 4, 2008
Appl. No.:
12/264462
Inventors:
Marie J. Archer - Alexandria VA, US
Baochuan Lin - Bethesda MD, US
David A. Stenger - Herndon VA, US
Assignee:
The Government of the United States of America, as represented by the Secretary of the Navy - Washington DC
International Classification:
C12P 19/34
C07H 21/02
US Classification:
435 912, 536 243
Abstract:
A method of: providing a solid surface having a dendrimer molecule bound thereto and a single-stranded probe nucleic acid immobilized to the dendrimer; contacting the solid surface with a sample suspected or known to contain a target ribonucleic acid; denaturing the target ribonucleic acid; and incubating the sample to allow hybridization of the denatured ribonucleic acid to the probe nucleic acids. The target ribonucleic acid is complementary to the probe nucleic acid.

Automated Sample-To-Microarray System

US Patent:
2007009, Apr 26, 2007
Filed:
Nov 14, 2006
Appl. No.:
11/559513
Inventors:
Frances Ligler - Potomac MD, US
David Stenger - Herndon VA, US
Jeff Erickson - Bethesda MD, US
Marie Archer - Alexandria VA, US
Assignee:
The Government of the US, as represented by the Secretary of the Navy - Washington DC
International Classification:
C12Q 1/68
C12M 1/34
US Classification:
435006000, 435287200
Abstract:
An apparatus having within or as part of a housing; a sample port; a microarray port; a lysis module; a purification module for containing a solid phase for binding of oligonucleotides; a thermocycling module for containing a polymerase chain reaction; a fragmentation module; and a microarray module for holding a microarray and a liquid in contact with the microarray. The apparatus is configured to be coupled to a device for: pumping a liquid through, in order, the lysis, purification, thermocycling, fragmentation, and microarray modules; sonicating any contents of the lysis module; thermocycling the thermocycling module to perform the polymerase chain reaction; heating the fragmentation module to fragment any oligonucleotides contained therein; circulating a fluid over the surface of the microarray; and performing one or more washing or staining steps on the microarray.

Large Scale Preparation Method For Functionalizing The Surface Of Magnetic Microparticles With An Inorganic Phosphorous Dendrimer

US Patent:
2014027, Sep 18, 2014
Filed:
Mar 13, 2014
Appl. No.:
14/208265
Inventors:
Marie J. Archer - Berwyn Heights MD, US
Baochuan Lin - Bethesda MD, US
International Classification:
C07F 9/6593
US Classification:
568 12
Abstract:
A method of attaching a phosphorous dendrimer onto magnetic microparticles by taking magnetic microparticles in a water-based solution, then performing a solvent exchange, then suspending the microparticles in a phosphorous dendrimer solution and shaking, then washing the microparticles with an organic solvent, and then washing the microparticles with a transition solvent. The solvent exchange is done by washing the microparticles with a first concentration of a transition solvent, then washing the microparticles with a second concentration of the transition solvent where the second concentration is greater than the first concentration, then washing the microparticles with an organic solvent, then washing the microparticles with the transition solvent, then washing the microparticles with the organic solvent, and then suspending the microparticles in the transition solvent. Also disclosed is the related phosphorous dendrimer made by this method.

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