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Martin Tremblay, 50Melrose, MA

Martin Tremblay Phones & Addresses

Melrose, MA   

Medford, MA   

San Diego, CA   

Work

Company: Smart & Biggar Address:

Mentions for Martin Tremblay

Career records & work history

Lawyers & Attorneys

Martin Tremblay Photo 1

Martin Tremblay - Lawyer

Office:
Smart & Biggar
Specialties:
Industrial/Mechanical, Software/Internet/Information Technologies, Electrical/Electronics, Patents, Industrial Designs, IP Management & Strategic Counselling, Cleantech
ISLN:
918034142
Admitted:
Registered Patent Agent, 2004; Registered to practise before the United States Patent and Trademark Office
University:
Concordia University, 2003; Concordia University, 2003; Concordia University, 2003; Professional Engineer

Martin Tremblay resumes & CV records

Resumes

Martin Tremblay Photo 51

Director, Chemistry At Infinity Pharmaceuticals, Inc.

Position:
Director at Infinity Pharmaceuticals
Location:
Greater Boston Area
Industry:
Pharmaceuticals
Work:
Infinity Pharmaceuticals - Cambridge, MA since Mar 2012
Director
Infinity Pharmaceuticals - Cambridge, MA Jul 2008 - Feb 2012
Associate Director, Chemistry
Infinity Pharmaceuticals - Cambridge, MA Oct 2006 - Jun 2008
Lead Sr. Scientist
Infinity Pharmaceuticals - Cambridge, MA May 2004 - Sep 2006
Sr. Scientist
Eisai - Andover, MA May 2003 - Apr 2004
Sr. Research Investigator
Eisai - Andover, MA Jul 2001 - Apr 2003
Research Investigator
Education:
The Scripps Research Institute 1999 - 2001
Postdoctoral, Chemistry
Université Laval 1993 - 1999
Doctorate, Medicinal chemistry
Martin Tremblay Photo 52

Martin Tremblay

Location:
United States
Martin Tremblay Photo 53

Supervisor Chez Videotron

Position:
supervisor at Videotron
Location:
Région de Miami/Fort Lauderdale , États-Unis
Industry:
Telecommunications
Work:
Videotron Occupe actuellement ce poste
supervisor

Publications & IP owners

Us Patents

Cyclopamine Analogues And Methods Of Use Thereof

US Patent:
7230004, Jun 12, 2007
Filed:
Aug 26, 2005
Appl. No.:
11/213534
Inventors:
Julian Adams - Boston MA, US
Alfredo C. Castro - Winchester MA, US
Michael A. Foley - Chestnut Hill MA, US
Somarajan Nair Janardanan Nair - Belmont MA, US
Marta Nevalainen - Quincy MA, US
James R. Porter - Brighton MA, US
Martin R. Tremblay - Melrose MA, US
Assignee:
Infinity Discovery, Inc. - Cambridge MA
International Classification:
A61K 31/438
A61K 31/4355
C07D 491/10
C07D 491/048
US Classification:
514278, 546 18, 546 15
Abstract:
The present invention provides compositions and methods for modulating smoothened-dependent pathway activation. The present invention provides analogs of cyclopamine that can be used to counteract the phenotypic effects of unwanted activation of a hedgehog pathway, such as resulting from hedgehog gain-of-function, Ptc loss-of-function or smoothened gain-of-function mutations. The compounds of the present invention are particularly useful in treating cancers.

Cyclopamine Analogues And Methods Of Use Thereof

US Patent:
7407967, Aug 5, 2008
Filed:
Apr 18, 2007
Appl. No.:
11/737035
Inventors:
Julian Adams - Boston MA, US
Alfredo C. Castro - Winchester MA, US
Michael A. Foley - Chestnut Hill MA, US
Somarajan Nair Janardanan Nair - Belmont MA, US
Marta Nevalainen - Quincy MA, US
James R. Porter - Brighton MA, US
Martin R. Tremblay - Melrose MA, US
Assignee:
Infinity Pharmaceuticals, Inc. - Cambridge MA
International Classification:
A61K 31/4355
C07D 491/048
US Classification:
514302, 546115, 546 15, 514278
Abstract:
The present invention provides compositions and methods for modulating smoothened-dependent pathway activation. The present invention provides analogs of cyclopamine that can be used to counteract the phenotypic effects of unwanted activation of a hedgehog pathway, such as resulting from hedgehog gain-of-function, Ptc loss-of-function or smoothened gain-of-function mutations. The compounds of the present invention are particularly useful in treating cancers.

Heterocyclic Cyclopamine Analogs And Methods Of Use Thereof

US Patent:
7648994, Jan 19, 2010
Filed:
Mar 7, 2008
Appl. No.:
12/044817
Inventors:
Alfredo C. Castro - Winchester MA, US
Michael J. Grogan - Winchester MA, US
Martin Tremblay - Melrose MA, US
Assignee:
Infinity Discovery, Inc. - Cambridge MA
International Classification:
A61K 31/4355
C07D 491/20
US Classification:
514278, 546 15, 546115, 514302
Abstract:
The present invention relates to steroidal alkaloids that can be used in the treatment of hedgehog pathway related disorders, particularly cancer.

Cyclopamine Analogs

US Patent:
7812164, Oct 12, 2010
Filed:
Dec 27, 2007
Appl. No.:
11/965688
Inventors:
Brian Austad - Tewksbury MA, US
Mark L. Behnke - Somerville MA, US
Alfredo C. Castro - Winchester MA, US
Michael J. Grogan - Winchester MA, US
Andre Lescarbeau - Somerville MA, US
Stephane Peluso - Somerville MA, US
Martin Tremblay - Melrose MA, US
Assignee:
Infinity Pharmaceuticals, Inc. - Cambridge MA
International Classification:
C07D 401/00
C07D 515/02
US Classification:
546 17, 546115, 549331, 549345
Abstract:
The invention provides novel derivatives of cyclopamine having the following formula:.

Cyclopamine Analogues And Methods Of Use Thereof

US Patent:
7875628, Jan 25, 2011
Filed:
Jul 10, 2008
Appl. No.:
12/171208
Inventors:
Julian Adams - Boston MA, US
Alfredo C. Castro - Winchester MA, US
Michael A. Foley - Chestnut Hill MA, US
Marta Nevalainen - Quincy MA, US
James R. Porter - Rowley MA, US
Martin R. Tremblay - Melrose MA, US
Assignee:
Infinity Discovery, Inc. - Cambridge MA
International Classification:
A61K 31/4355
C12N 9/99
US Classification:
514302, 514278, 435184
Abstract:
The present invention provides compositions and methods for modulating smoothened-dependent pathway activation. The present invention provides analogs of cyclopamine that can be used to counteract the phenotypic effects of unwanted activation of a hedgehog pathway, such as resulting from hedgehog gain-of-function, Ptc loss-of-function or smoothened gain-of-function mutations. The compounds of the present invention are particularly useful in treating cancers.

Cyclopamine Lactam Analogs And Methods Of Use Thereof

US Patent:
7964590, Jun 21, 2011
Filed:
Mar 7, 2008
Appl. No.:
12/044878
Inventors:
Alfredo C. Castro - Winchester MA, US
Michael J. Grogan - Winchester MA, US
Andre Lescarbeau - Somerville MA, US
Martin Tremblay - Melrose MA, US
Assignee:
Infinity Discovery, Inc. - Cambridge MA
International Classification:
A61K 31/55
C07D 491/20
US Classification:
514215, 540521, 540578
Abstract:
The present invention relates to steroidal alkaloids useful in the treatment of hedgehog pathway related disorders, particularly cancer.

Methods Of Use Of Cyclopamine Analogs

US Patent:
8017648, Sep 13, 2011
Filed:
Dec 27, 2007
Appl. No.:
11/965675
Inventors:
Alfredo C. Castro - Winchester MA, US
Michael J. Grogan - Winchester MA, US
Karen J. McGovern - Groton MA, US
Martin Tremblay - Melrose MA, US
Assignee:
Infinity Pharmaceuticals, Inc. - Cambridge MA
International Classification:
A61K 31/35
A61K 31/27
A61K 31/54
A61K 31/56
US Classification:
514455, 514 47, 514169, 514222, 514226, 514261, 514262, 514278
Abstract:
The invention provides methods for treating various conditions using derivatives of cyclopamine having the following formula:.

Methods Of Use Of Cyclopamine Analogs

US Patent:
8227509, Jul 24, 2012
Filed:
Jul 27, 2011
Appl. No.:
13/191545
Inventors:
Alfredo C. Castro - Winchester MA, US
Michael J. Grogan - Winchester MA, US
William Matsui - Baltimore MD, US
Karen J. McGovern - Groton MA, US
Martin R. Tremblay - Melrose MA, US
Assignee:
Infinity Pharmaceuticals, Inc. - Cambridge MA
International Classification:
A61K 315/35
A61K 31/27
A61K 31/54
A61K 31/56
US Classification:
514455, 514 47, 514169, 514278
Abstract:
The invention provides methods for treating various conditions using derivatives of cyclopamine having the following formula:.

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