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Mark Ammirati, 6417 Dunns Ct, Stonington, CT 06378

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17 Dunns Ct, Stonington, CT 06378    860-5362390   

Mystic, CT   

Colchester, CT   

Meriden, CT   

Southbury, CT   

17 Dunns Ct, Stonington, CT 06378    860-9784388   

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Position: Professional/Technical

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Degree: Graduate or professional degree

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Mark Ammirati Photo 12

Mark Ammirati

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Us Patents

Crystal Structure Of Staphylococcus Undecaprenyl Pyrophosphate Synthase And Uses Thereof

US Patent:
2005020, Sep 22, 2005
Filed:
Oct 17, 2003
Appl. No.:
10/688167
Inventors:
Mark Ammirati - Stonington CT, US
Jayvardhan Pandit - Mystic CT, US
International Classification:
C12N009/12
G06F019/00
G01N033/48
G01N033/50
US Classification:
435194000, 702019000
Abstract:
The invention is directed generally to the structure of prenyltransferases, particularly undecaprenyl pyrophosphate synthase, an enzyme important in bacterial cell wall synthesis. The invention relates to the crystal structure of undecaprenyl pyrophosphate synthase from and the interaction with a cofactor and ligands. The invention also relates to the structure of ligand and cofactor binding sites.

Method Of Inhibition Of Human Glycogen Phosphorylase

US Patent:
2002003, Mar 14, 2002
Filed:
Aug 5, 1999
Appl. No.:
09/369214
Inventors:
VIRGINIA LEIGH RATH - STONINGTON CT, US
DENNIS JAY HOOVER - MYSTIC CT, US
MARK AMMIRATI - STONINGTON CT, US
International Classification:
C12N009/12
C12Q001/48
G06F019/00
US Classification:
435/194000, 702/027000, 435/015000
Abstract:
The present invention is directed to a novel binding site for a glycogen phosphorylase inhibitor found within a glycogen phosphorylase enzyme. The novel binding site allows the design novel of glycogen phosphorylase inhibitors.

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