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Mark A Burlingame, 62845 45Th St, Oakland, CA 94608

Known as:
Mark Alma Burlingame Nark A Burlingame
Related to:
Charlotte B Burlingame 91 Larry C Burlingame 70

Mark Burlingame Phones & Addresses

845 45Th St, Emeryville, CA 94608    510-6534737   

Oakland, CA   

1075 Calle Empinado, Novato, CA 94949    415-8837059   

59 Albion St, San Francisco, CA 94103    415-6262540   

Berkeley, CA   

Chico, CA   

Alameda, CA   

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Mentions for Mark A Burlingame

Career records & work history

Medicine Doctors

Mark W. Burlingame

Specialties:
Congenital Cardiac Surgery (Thoracic Surgery)
Work:
Cardiothoracic Surgeons Lancaster General Health
540 N Duke St STE 110, Lancaster, PA 17602
717-2904995 (phone) 717-2996577 (fax)
Education:
Medical School
Creighton University School of Medicine
Graduated: 1975
Procedures:
Lung Biopsy, Thoracic Aortic Aneurysm Repair, Abdominal Aortic Aneurysm, Aortic Aneurysm Repair, Coronary Artery Bypass, Heart Valve Procedures, Removal Procedures on the Lungs and Pleura, Septal Defect Repair, Thoracoscopy
Conditions:
Congenital Anomalies of the Heart, Lung Cancer
Languages:
English
Description:
Dr. Burlingame graduated from the Creighton University School of Medicine in 1975. He works in Lancaster, PA and specializes in Congenital Cardiac Surgery (Thoracic Surgery). Dr. Burlingame is affiliated with Lancaster General Hospital.

Mark Burlingame resumes & CV records

Resumes

Mark Burlingame Photo 43

Mark Burlingame

Location:
San Francisco, CA
Industry:
Biotechnology
Skills:
Drug Discovery, Molecular Biology, Biochemistry, Protein Purification, Purification, Hplc, Lc Ms, Biotechnology, Organic Synthesis
Mark Burlingame Photo 44

Mark Burlingame

Mark Burlingame Photo 45

Mark Burlingame

Publications & IP owners

Us Patents

Racemic Thioesters For Production Of Polyketides

US Patent:
6492562, Dec 10, 2002
Filed:
Jan 27, 2000
Appl. No.:
09/492733
Inventors:
Gary Ashley - Alameda CA
Isaac C. Chan-Kai - Hayward CA
Mark A. Burlingame - San Francisco CA
Assignee:
Kosan Biosciences, Inc. - Hayward CA
International Classification:
C07C 1100
US Classification:
568 75, 424 7051
Abstract:
Facile methods for preparing diketide and triketide thioesters are disclosed. The resulting thioesters may be used as intermediates in the synthesis of desired polyketides, and may contain functional groups which ultimately reside in side chains on the resulting polyketide and thus can be used further to manipulate the polyketide so as form derivatives. The polyketides produced may also be tailored by glycosylation, hydroxylation and the like. New polyketides and their derivatives and tailored forms are thereby produced.

Motilide Compounds

US Patent:
6562795, May 13, 2003
Filed:
Feb 15, 2001
Appl. No.:
09/788314
Inventors:
Gary Ashley - Alameda CA
Mark Burlingame - San Francisco CA
Christopher Carreras - Belmont CA
Daniel Santi - San Francisco CA
Assignee:
Kosan Biosciences, Inc. - Hayward CA
International Classification:
A61K 3170
US Classification:
514 29, 536 72, 536 74
Abstract:
The present invention provides novel macrolide compounds of the formulas wherein: R is hydroxyl or methoxy; R is selected from the group consisting of hydrogen, hydroxyl, halide, NH , OR , âwhere R is C -C alkyl, C -C alkenyl, C -C alkynyl, aryl or heteroaryl and R and R are each independently hydrogen, C -C alkyl, C -C alkenyl, C -C alkynyl, or aryl; R and R are each independently selected from the group consisting of hydrogen, C -C alkyl, C -C alkenyl, C -C alkynyl, aryl, alkylaryl, alkenylaryl, alkynylaryl or R and R together form a cycloalkyl or a cycloaryl moiety; R is hydrogen or methyl; R is hydrogen, hydroxyl, oxo, or together with R and the carbons to which they are attached form a cyclic carbonate; R is hydrogen, hydroxyl, OR where R is C -C alkyl, C -C alkenyl, C -C alkynyl, or together with R and the carbons to which they are attached form a cyclic carbonate; R is methyl, C -C alkyl, C -C alkenyl, C -C alkynyl, alkylaryl, alkenylaryl, alkynylaryl, amidoalkylaryl, amidoalkenylaryl, or amidoalkynylaryl; R is C -C alkyl, C -C alkenyl, C -C alkynyl, alkylaryl, alkenylaryl, alkynylaryl, amidoalkylaryl, amidoalkenylaryl, or amidoalkynylaryl; and, x is a single or a double bond.

Motilide Compounds

US Patent:
6750205, Jun 15, 2004
Filed:
Apr 7, 2003
Appl. No.:
10/409429
Inventors:
Gary Ashley - Alameda CA
Mark Burlingame - San Francisco CA
Christopher Carreras - Belmont CA
Daniel Santi - San Francisco CA
Assignee:
Kosan Biosciences, Inc. - Hayward CA
International Classification:
A61K 3170
US Classification:
514 29, 536 72, 536 74
Abstract:
The present invention provides novel macrolide compounds of the formulas wherein: R is hydroxyl or methoxy; R is selected from the group consisting of hydrogen, hydroxyl, halide, NH , OR , where R is C -C alkyl, C -C alkenyl, C -C alkynyl, aryl or heteroaryl and R and R are each independently hydrogen, C -C alkyl, C -C alkenyl, C -C alkynyl, or aryl; R and R are each independently selected from the group consisting of hydrogen, C -C alkyl, C -C alkenyl, C -C alkynyl, aryl, alkylaryl, alkenylaryl alkynylaryl or R and R together form a cycloalkyl or a cycloaryl moiety; R is hydrogen or methyl; R is hydrogen, hydroxyl, oxo, or together with R and the carbons to which they are attached form a cyclic carbonate; R is hydrogen, hydroxyl, OR where R is C -C alkyl, C -C alkenyl, C -C alkynyl, or together with R and the carbons to which they are attached form a cyclic carbonate; R is methyl, C -C alkyl, C -C alkenyl, C -C alkynyl, alkylaryl, alkenylaryl, alkynylaryl, amidoalkylaryl, amidoalkenylaryl, or amidoalkynylaryl; R is C -C alkyl, C -C alkenyl, C -C alkynyl, alkylaryl, alkenylaryl, alkynylaryl, amidoalkylaryl, amidoalkenylaryl, or amidoalkynylaryl; and, x is a single or a double bond.

Polyketides And Antibiotics

US Patent:
7022825, Apr 4, 2006
Filed:
Aug 8, 2002
Appl. No.:
10/215964
Inventors:
Gary Ashley - Alameda CA, US
Isaac C. Chan-Kai - Hayward CA, US
Mark A. Burlingame - San Francisco CA, US
Assignee:
Kosan Biosciences, Inc. - Hayward CA
International Classification:
C07H 17/08
A16K 31/7048
C12P 19/62
US Classification:
536 72, 514 29, 435 75
Abstract:
Facile methods for preparing diketide and triketide thioesters are disclosed. The resulting thioesters may be used as intermediates in the synthesis of desired polyketides, and may contain functional groups which ultimately reside in side chains on the resulting polyketide and thus can be used further to manipulate the polyketide so as form derivatives. The polyketides produced may also be tailored by glycosylation, hydroxylation and the like. New polyketides and their derivatives and tailored forms are thereby produced.

Synthetic Techniques And Intermediates For Polyhydroxy Dienyl Lactones And Mimics Thereof

US Patent:
7342124, Mar 11, 2008
Filed:
Apr 2, 2004
Appl. No.:
10/817532
Inventors:
David C. Myles - Kensington CA, US
Mark Burlingame - Oakland CA, US
Simon James Shaw - San Francisco CA, US
Kurt F. Sundermann - Burlingame CA, US
Brian Scott Freeze - Philadelphia PA, US
Ignació Brouard Martin - Canary Islands, ES
Tomoyasu Hirose - Tokyo, JP
Assignee:
The Trustees Of The University Of Pennsylvania - Philadelphia PA
Kosan Biosciences, Inc. - Hayward CA
International Classification:
C07F 9/02
C07C 67/02
US Classification:
556404, 560262, 568 11
Abstract:
Synthetic methods and intermediates useful in the preparation of lactone containing compounds such as discodermolide and compounds which mimic the chemical or biological activity of discodermolide are provided.

Motilide Compounds

US Patent:
7582611, Sep 1, 2009
Filed:
May 2, 2006
Appl. No.:
11/416519
Inventors:
Yaoquan Liu - Castro Valley CA, US
Christopher Carreras - Belmont CA, US
David C. Myles - Kensington CA, US
Yong Li - Palo Alto CA, US
Simon James Shaw - San Francisco CA, US
Hong Fu - Union City CA, US
Yue Chen - Hayward CA, US
Hao Zheng - Hayward CA, US
Yandong Li - San Jose CA, US
Mark A. Burlingame - Oakland CA, US
Assignee:
Pfizer Inc. - New York NY
International Classification:
A61K 31/70
C07H 17/08
US Classification:
514 29, 536 72, 536 73, 536 74
Abstract:
Compounds having a structure according to formula (I).

7-Quinolyl Ketolide Antibacterial Agents

US Patent:
7595300, Sep 29, 2009
Filed:
Dec 7, 2006
Appl. No.:
11/636206
Inventors:
Simon James Shaw - San Francisco CA, US
Gary W Ashley - Alameda CA, US
Mark A. Burlingame - Oakland CA, US
Assignee:
Kosan Biosciences Incorporated - Princeton NJ
International Classification:
A61K 31/70
C07H 17/08
US Classification:
514 29, 536 74
Abstract:
15-fluoroketolides of the formula.

Sixteen-Membered Macrolide Compounds

US Patent:
2002012, Sep 12, 2002
Filed:
Sep 24, 2001
Appl. No.:
09/969177
Inventors:
Leonard Katz - Oakland CA, US
Gary Ashley - Alameda CA, US
Mark Burlingame - San Francisco CA, US
Steven Dong - San Francisco CA, US
Hong Fu - Union City CA, US
Yong Li - Palo Alto CA, US
David Myles - Kensington CA, US
International Classification:
A61K031/7048
C07H017/08
US Classification:
514/030000, 536/007100
Abstract:
The present invention provides novel sixteen-membered macrolide compounds that are useful as anti-infective agents or as intermediates thereto. The present invention also provides methods for the preparation of these compounds, and methods and formulations for their use. In one aspect of the present invention, sixteen-membered macrolide possessing a side chain Z are provided where Z is aliphatic, aryl, alkylaryl, halide, NOR, NNHR, or —W—Rwhere W is O, S, NC( O)R, NC( O)OR, NC( O)NHRor NRwhere Rand Rare each independently hydrogen, aliphatic, aryl or alkylaryl. In another aspect of the present invention, bicyclic compounds are provided where one of the cyclic-components is a sixteen-membered macrolide and the other is a cyclic moiety whose cyclic structure is formed by between 3 and 10 atoms. In another aspect of the present invention, sixteen-membered macrolide compounds that bind to the domain II region of the 23S RNA are provided.

Possible Relatives

David H Burlingame  Deborah A Burlingame  Dana S Burlingame  Daniel A Burlingame  Dennis R Burlingame  Darlene A Burlingame  Diane J Burlingame  Mark W Johnson  Mark E Stamps  Mark Stancil 

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