Inventors:
- Oakland CA, US
Kaixiang ZHANG - Irvine CA, US
Md Monsur ALI - Irvine CA, US
Mark A. ECKERT - Irvine CA, US
Feng LI - Irvine CA, US
Enrico GRATTON - Irvine CA, US
MIchelle A. DIGMAN - Irvine CA, US
Louai LABANIEH - Irvine CA, US
Mengrou LU - Irvine CA, US
International Classification:
G01N 33/574
G01N 33/569
Abstract:
In alternative embodiments, the invention provides high throughput, multiplexed systems or methods for detecting a biological, a physiological or a pathological maker, or a single molecule or a single cell using a droplet microfluidics system integrated with use of a sensor or a sensing system, an aptamer, or a DNAzyme. In alternative embodiments, the sensor or sensing system comprises a nucleic acid based, an antibody based, an enzyme based or a chemical based sensor or sensing system. In alternative embodiments, the invention provides methods for detecting a biological, a physiological or a pathological marker, or a single molecule or a single cell using a droplet system integrated with rapid and sensitive fluorescence detection systems including, for example, a 3D Particle Detector. In alternative embodiments, the invention provides systems comprising Integrated Comprehensive Droplet Digitial Detection (IC 3D).
