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Mark E Hediger, 62418 Stearns Rd, Marlboro, MA 01752

Known as:
Diger H Mark Mark R
Related to:
Cole J Hediger 27 Madison Hediger 24

Mark Hediger Phones & Addresses

418 Stearns Rd, Marlborough, MA 01752    508-4816293   

Richmond, CA   

Chicago, IL   

Park Ridge, IL   

Oklahoma City, OK   

Oakland, CA   

418 Stearns Rd, Marlborough, MA 01752    508-4987661   

Work

Position: Professional/Technical

Education

Degree: Graduate or professional degree

Emails

i***[email protected]
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Mentions for Mark E Hediger

Publications & IP owners

Us Patents

Multiple Substituted Fluoromethanes As Selective And Bioactive Isosteres

US Patent:
2012030, Nov 29, 2012
Filed:
Feb 3, 2011
Appl. No.:
13/576911
Inventors:
Mark E. Hediger - Marlborough MA, US
Assignee:
MEH ASSOCIATES, INC. - Marlborough MA
International Classification:
A61K 31/198
C12N 9/99
G01N 21/75
C07C 229/20
C07C 323/63
C07C 323/58
C07H 5/10
A61K 31/70
C07C 323/25
A61K 31/145
A61K 31/19
C07C 279/14
C07H 19/207
A61K 31/7076
C07D 213/66
A61K 31/44
A61P 31/04
A61P 33/00
A61P 33/06
A61P 33/02
C07C 229/24
US Classification:
514 47, 562571, 514561, 435184, 435 15, 562575, 562426, 514562, 562557, 536122, 514 23, 564501, 514665, 562598, 514557, 562560, 514565, 536 2623, 546298, 514350
Abstract:
Disclosed herein are substituted fluoromethanes; pharmaceutical compositions comprising a therapeutically effective amount of the same; processes for preparing these fluoromethanes; and methods of using the same in alleviating infection and parasitism. Also disclosed are methods for identifying substituted fluoromethanes for modulating the activity of receptors and enzymes that bind and/or modify phosphate containing ligands and substrates.

Method Of Identifying Inhibitors Of Cdc25

US Patent:
2002018, Dec 5, 2002
Filed:
Mar 1, 2001
Appl. No.:
09/797500
Inventors:
Neil Taylor - Sydney, AU
David Borhani - Worcester MA, US
David Epstein - Belmont MA, US
Johannes Rudolph - Durham NC, US
Kurt Ritter - Newton MA, US
Taro Fujimori - Shrewsbury MA, US
Simon Robinson - Stow MA, US
Jens Eckstein - Arlington MA, US
Andreas Haupt - Schwetzingen, DE
Nigel Walker - Burlingame CA, US
Richard Dixon - Jefferson MA, US
Deborah Choquette - Rutland MA, US
Jill Blanchard - Arlington MA, US
Arthur Kluge - Lincoln MA, US
Kollol Pal - Needham MA, US
Nicholas Bockovich - Malden MA, US
Jon Come - Cambridge MA, US
Mark Hediger - Marlboro MA, US
International Classification:
A61K038/17
G06F019/00
G01N033/48
G01N033/50
C12N009/64
US Classification:
514/012000, 435/226000, 702/019000
Abstract:
The present invention relates to polypeptides which comprise the ligand binding domain of Cdc25, crystalline forms of these polypeptides and the use of these crystalline forms to determine the three dimensional structure of the catalytic domain of Cdc25. The invention also relates to the use of the three dimensional structure of the Cdc25 catalytic domain in methods of designing and/or identifying potential inhibitors of Cdc25 activity, for example, compounds which inhibit the binding of a native substrate to the Cdc25 catalytic domain.

Possible Relatives

Donald Hediger  James D Hediger  Kenneth C Hediger  Kevin L Hediger  Lynn Hediger  Scott J Hediger  Mark W Johnson  Mark E Stamps  Mark Stancil  Mark D Stancombe 

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