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Mark A Mortellaro, 56Clarksburg, MD

Mark Mortellaro Phones & Addresses

Clarksburg, MD   

Carlisle, PA   

San Francisco, CA   

Newville, PA   

804 Apache Ct, Frederick, MD 21701    240-3796135    301-6634375    301-3796135   

Woodstock, GA   

Roswell, GA   

Columbus, OH   

East Lansing, MI   

804 Apache Ct, Frederick, MD 21701    301-3796135   

Work

Position: Food Preparation and Serving Related Occupations

Education

Degree: Associate degree or higher

Mentions for Mark A Mortellaro

Mark Mortellaro resumes & CV records

Resumes

Mark Mortellaro Photo 10

Senior Principal Regulatory Scientist

Location:
12344 Cherry Branch Dr, Clarksburg, MD 20871
Industry:
Medical Devices
Work:
Senseonics, Incorporated
Senior Principal Regulatory Scientist
Senseonics, Incorporated Aug 2002 - Mar 2018
Director of Chemistry, R and D
Sano Intelligence Aug 2002 - Mar 2018
Vice President of Sensor Development
Roche 1996 - 2002
Research Chemist
Education:
The Ohio State University 1990 - 1994
Doctorates, Doctor of Philosophy, Organic Chemistry
Youngstown State University 1986 - 1990
Bachelors, Bachelor of Science, Chemistry
Mcdonald High School
Skills:
R&D, Chemistry, Organic Chemistry, Project Management, Medical Devices, Research and Development, Fluorescence, Laboratory, Biotechnology, Hplc, Uv/Vis, Polymers, Fda, Life Sciences, Technology Transfer, Validation, Gmp, Iso 13485, Lifesciences, U.s. Food and Drug Administration, High Performance Liquid Chromatography, Medical Device R&D, Optical Sensors, Combination Products, Analyte Sensors, Molecular Recognition, Quality System Compliance
Certifications:
Learning Gantt Charts
Project Management: Solving Common Project Problems
Project Management Simplified
Project Management Foundations: Stakeholders
Project Management Foundations: Communication
Mark Mortellaro Photo 11

Mark Mortellaro

Mark Mortellaro Photo 12

Mark Mortellaro

Location:
United States
Mark Mortellaro Photo 13

Mark Mortellaro

Location:
United States

Publications & IP owners

Us Patents

Oxidation Resistant Indicator Molecules

US Patent:
7851225, Dec 14, 2010
Filed:
Nov 30, 2007
Appl. No.:
11/948419
Inventors:
Mark Alan Mortellaro - Frederick MD, US
Aneta Modzelewska - Germantown MD, US
Assignee:
Sensors for Medicine and Science, Inc. - Germantown MD
International Classification:
G01N 33/66
G01N 33/50
G01N 33/00
C07F 5/02
C07F 5/00
US Classification:
436 95, 436164, 436 94, 436 93, 436 91, 562 7, 562 1
Abstract:
Compounds having enhanced oxidation stability are disclosed. The compounds have an aryl boronic acid residue having one or more electron withdrawing groups on the aromatic moiety which contains the boronic acid residue, such that the molecule has enhanced oxidation resistance as compared to a corresponding molecule without the one or more electron withdrawing groups.

Luminescent Indicator Dye And Optical Sensor

US Patent:
8097725, Jan 17, 2012
Filed:
Dec 3, 2004
Appl. No.:
11/003163
Inventors:
Huarui He - Alpharetta GA, US
Mark A. Mortellaro - Frederick MD, US
Susanne T. Young - Norcross GA, US
Assignee:
Roche Diagnostics Operations, Inc. - Indianapolis IN
International Classification:
C07D 221/14
US Classification:
546 79, 73435
Abstract:
The present invention relates to a chemical compound that has applications as a luminescent indicator dye, and to an optical sensor, typically employed for determination of near-neutral pH values of aqueous samples. The optical sensor has particular application in the pH determination of body liquids such as, for example, blood, plasma and serum.

Oxidation Resistant Indicator Molecules

US Patent:
8143068, Mar 27, 2012
Filed:
Dec 13, 2010
Appl. No.:
12/966693
Inventors:
Mark Alan Mortellaro - Frederick MD, US
Aneta Modzelewska - Germantown MD, US
Assignee:
Sensors for Medicine and Science, Inc. - Germantown MD
International Classification:
G01N 33/66
G01N 33/00
G01N 21/00
C07F 5/02
US Classification:
436 95, 436164, 436 94, 436 93, 436 91, 562 7, 562 1
Abstract:
Compounds having enhanced oxidation stability are disclosed. The compounds have an aryl boronic acid residue having one or more electron withdrawing groups on the aromatic moiety which contains the boronic acid residue, such that the molecule has enhanced oxidation resistance as compared to a corresponding molecule without the one or more electron withdrawing groups.

Oxidation-Resistant Indicator Macromolecule

US Patent:
2007001, Jan 18, 2007
Filed:
Jul 17, 2006
Appl. No.:
11/487435
Inventors:
Kandace Merical - Mt. Airy MD, US
Arthur Colvin - Mt. Airy MD, US
Mark Mortellaro - Frederick MD, US
Assignee:
Sensors for Medicine and Science - Germantown MD
International Classification:
A61K 49/00
US Classification:
424009100
Abstract:
In one aspect, the present invention relates to an implantable device for detecting the presence or concentration of an analyte in an aqueous environment in vivo. The device includes a macromolecule that comprises a copolymer of: a) one or more indicator component monomers which individually are not sufficiently water soluble to permit their use in an aqueous environment for detecting the presence or concentration of said analyte; b) one or more hydrophilic monomers; and c) one or more catalytic antioxidant monomers; such that the macromolecule is capable of detecting the presence or concentration of the analyte in an aqueous environment. The presence of the catalytic antioxidant reduces or prevents oxidative damage to the macromolecule.

Detecting And Correcting For Interference In An Analyte Monitoring System

US Patent:
2022028, Sep 15, 2022
Filed:
May 26, 2022
Appl. No.:
17/825137
Inventors:
- Germantown MD, US
Mark Mortellaro - Germantown MD, US
Abhi Chavan - Germantown MD, US
Venkata Velvadapu - Germantown MD, US
Philip Huffstetler - Germantown MD, US
James Masciotti - Germantown MD, US
Patricia Sanchez - Germantown MD, US
Assignee:
Senseonics, Incorporated - Germantown MD
International Classification:
A61B 5/1495
A61B 5/145
A61B 5/1455
A61B 5/1459
A61B 5/00
A61B 5/07
Abstract:
A sensor, system, and method for detecting and correcting for an effect on an analyte indicator of an analyte sensor. The analyte indicator may be configured to exhibit a first detectable property that varies in accordance with an analyte concentration and an effect on (e.g., degradation of) the analyte indicator. The analyte sensor may also include an interferent indicator configured to exhibit a second detectable property (e.g., absorption) that varies in accordance the effect on the analyte indicator. The analyte sensor may generate (i) an analyte measurement based on the first detectable property exhibited by the analyte indicator and (ii) an interferent measurement based on the second detectable property exhibited by the interferent indicator. The analyte sensor may be part of a system that also includes a transceiver. The transceiver may use the analyte and interferent measurements to calculate an analyte level.

Detecting And Correcting For Changes To An Analyte Indicator

US Patent:
2023010, Apr 6, 2023
Filed:
Dec 2, 2022
Appl. No.:
18/061334
Inventors:
- Germantown MD, US
Mark Mortellaro - Germantown MD, US
Abhi Chavan - Germantown MD, US
Venkata Velvadapu - Germantown MD, US
Philip Huffstetler - Germantown MD, US
Tina HyunJung Kim - Germantown MD, US
James Masciotti - Germantown MD, US
Assignee:
Senseonics, Incorporated - Germantown MD
International Classification:
A61B 5/1495
A61B 5/145
A61B 5/1455
A61B 5/1459
A61B 5/00
A61B 5/07
Abstract:
A sensor, system, and method for detecting and correcting for changes to an analyte indicator of an analyte sensor. The analyte indicator may be configured to exhibit a first detectable property that varies in accordance with an analyte concentration and an extent to which the analyte indicator has degraded. The analyte sensor may also include a degradation indicator configured to exhibit a second detectable property that varies in accordance with an extent to which the degradation indicator has degraded. The analyte sensor may generate (i) an analyte measurement based on the first detectable property exhibited by the analyte indicator and (ii) a degradation measurement based on the second detectable property exhibited by the degradation indicator. The analyte sensor may be part of a system that also includes a transceiver. The transceiver may use the analyte and degradation measurements to calculate an analyte level.

Identification Of Degradative Species

US Patent:
2021014, May 13, 2021
Filed:
Nov 13, 2020
Appl. No.:
17/097678
Inventors:
- Germantown MD, US
Mark Mortellaro - Germantown MD, US
Assignee:
Senseonics, Incorporated - Germantown MD
International Classification:
G01N 21/64
G01N 33/52
G01N 33/66
A61B 5/145
A61B 5/1486
Abstract:
A sensor (e.g., an optical sensor) that may be implanted within a living animal (e.g., a human) and may be used to measure an analyte (e.g., glucose or oxygen) in a medium (e.g., interstitial fluid, blood, or intraperitoneal fluid) within the animal. The sensor may include a sensor substrate, electrode or housing, an analyte indicator covering at least a portion of the sensor, and one or more probes that identify degradative species in an environment of the sensor.

Detecting And Correcting For Changes To An Analyte Indicator

US Patent:
2021005, Feb 25, 2021
Filed:
Nov 9, 2020
Appl. No.:
17/092830
Inventors:
- Germantown MD, US
Mark Mortellaro - Germantown MD, US
Abhi Chavan - Germantown MD, US
Venkata Velvadapu - Germantown MD, US
Philip Huffstetler - Germantown MD, US
Tina HyunJung Kim - Germantown MD, US
James Masciotti - Germantown MD, US
Assignee:
Senseonics, Incorporated - Germantown MD
International Classification:
A61B 5/1495
A61B 5/145
A61B 5/1455
A61B 5/1459
A61B 5/00
A61B 5/07
Abstract:
A sensor, system, and method for detecting and correcting for changes to an analyte indicator of an analyte sensor. The analyte indicator may be configured to exhibit a first detectable property that varies in accordance with an analyte concentration and an extent to which the analyte indicator has degraded. The analyte sensor may also include a degradation indicator configured to exhibit a second detectable property that varies in accordance with an extent to which the degradation indicator has degraded. The analyte sensor may generate (i) an analyte measurement based on the first detectable property exhibited by the analyte indicator and (ii) a degradation measurement based on the second detectable property exhibited by the degradation indicator. The analyte sensor may be part of a system that also includes a transceiver. The transceiver may use the analyte and degradation measurements to calculate an analyte level.

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