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Megan S Mcafee, 36Wayland, MA

Megan Mcafee Phones & Addresses

Wayland, MA   

Seattle, WA   

Mercer Island, WA   

Chandler, AZ   

West Linn, OR   

Tualatin, OR   

Mentions for Megan S Mcafee

Megan Mcafee resumes & CV records

Resumes

Megan Mcafee Photo 23

Scientist Ii

Location:
Seattle, WA
Work:
Takeda Pharmaceuticals
Scientist Ii
Education:
Arizona State University 2011 - 2015
Doctorates, Doctor of Philosophy, Philosophy
Megan Mcafee Photo 24

Megan Mcafee

Megan Mcafee Photo 25

Megan Mcafee

Skills:
Mcafee

Publications & IP owners

Us Patents

Merkel Cell Polyomavirus T Antigen-Specific Tcrs And Uses Thereof

US Patent:
2021025, Aug 19, 2021
Filed:
May 15, 2019
Appl. No.:
17/055969
Inventors:
- Seattle WA, US
Megan MCAFEE - Seattle WA, US
Natalie MILLER - Seattle WA, US
Kelly PAULSON - Shoreline WA, US
David KOELLE - Seattle WA, US
Thomas SCHMITT - Seattle WA, US
Candice CHURCH - Seattle WA, US
International Classification:
A61K 35/17
A61K 38/20
A61K 38/21
C12N 5/0783
Abstract:
The present disclosure provides binding proteins and TCRs with high affinity and specificity against Merkel cell polyomavirus T antigen epitopes or peptides, T cells expressing such high affinity Merkel cell polyomavirus T antigen specific TCRs, nucleic acids encoding the same, and compositions for use in treating Merkel cell carcinoma.

High Affinity Merkel Cell Polyomavirus T Antigen-Specific Tcrs And Uses Thereof

US Patent:
2020003, Jan 30, 2020
Filed:
Nov 14, 2017
Appl. No.:
16/348378
Inventors:
- Seattle WA, US
Megan S. McAfee - Seattle WA, US
Natalie J. Miller - Seattle WA, US
Kelly Garneski Paulson - Shoreline WA, US
David Martin Koelle - Seattle WA, US
Thomas M. Schmitt - Seattle WA, US
Candice Church - Seattle WA, US
International Classification:
A61K 35/17
C07K 14/725
C07K 16/28
Abstract:
The present disclosure provides binding proteins and TCRs with high affinity and specificity against Merkel cell Poly-omavirus T antigen epitopes or peptides, T cells expressing such high affinity Merkel cell polyomavirus T antigen specific TCRs, nucleic acids encoding the same, and compositions for use in treating Merkel cell carcinoma.

High Affinity Mage-A1-Specific Tcrs And Uses Thereof

US Patent:
2020001, Jan 16, 2020
Filed:
Sep 13, 2019
Appl. No.:
16/571013
Inventors:
- Seattle WA, US
Thomas SCHMITT - Seattle WA, US
Megan MCAFEE - Seattle WA, US
International Classification:
C07K 14/725
A61P 35/00
A61K 35/17
C07K 14/705
C12N 5/0783
Abstract:
The present disclosure provides TCRs with high or enhanced affinity against various tumor associated antigens (including human MAGE-A1 epitopes), T cells expressing such high affinity antigen-specific TCRs, nucleic acids encoding the same, and compositions for use in treating diseases or disorders in which cells overexpress one or more of these antigens, such as in cancer.

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