Melvin P Ehrlich, 97East Hills, NY

2002017, Nov 21, 2002

Nov 8, 1999

09/436207

JOSEPH CANTER - LEXINGTON MA, US
YONGWU YANG - BELMONT MA, US
WANGLONG ZHOU - READING MA, US
VICTOR SAPIRSTEIN - POUND RIDGE NY, US
MELVIN EHRLICH - ROSLYN ESTATES NY, US
JAMES HARRISON - RINGWOOD NJ, US
EUGENE KATSMAN - ARLINGTON MA, US
OMANAND KOUL - BURLINGTON MA, US
MICHAEL LU - LEXINGTON MA, US
MICHAEL GREENWALD - BROOKLINE MA, US

C12Q001/70

435/005000

The present invention relates to an apparatus and method for disease detection. The apparatus and method use a radiation source to irradiate a sample. An analyzer measures the absorption and/or emission spectra from the sample to detect the presence of the disease state in the sample. In this regard, a comparator may compare the measured spectra with the spectrum of a control. Analysis of the parameters of the spectra including, but not limited to, peak intensity wavelength, amplitude at the peak intensity, area ratio of left and right portions of the emission spectra, and shifts of the peak intensity wavelength, allows determination of HIV infection, Hepatitis A, B and C, and other diseases. Selective absorbents, such as C-M Affi Gel Blue and activated charcoal, may be used to treat the samples before measurements, which is found to improve discrimination of diseased and non-diseased samples. The present invention is capable of detecting HIV infection at a stage when it is still undetectable by conventional diagnosis methods.

6159159, Dec 12, 2000

Dec 31, 1998

9/224182

Joseph M. Canter - Lexington MA
Yongwu Yang - Belmont MA
Wanglong Zhou - Reading MA
Victor S. Sapirstein - Pound Ridge NY
Melvin P. Ehrlich - Roslyn Estates NY
James S. Harrison - Ringwood NJ
Eugene Katsman - Arlington MA
Omanand Koul - Burlington MA
Michael Y. Lu - Lexington MA
Michael A. Greenwald - Brookline MA

SerOptix, Inc. - Woburn MA

A61B 1000

600551

A quantitative process for monitoring female fertility cycle wherein the process involves directing a laser beam, preferably generated by a diode laser, onto an area of a slide containing an air-dried sample of a female body fluid. The diffraction pattern resulting from the sample is detected by a two-dimensional photo diode array and analyzed by a microprocessor. If a ferning pattern exists, such pattern will generate a characteristic structure in the diffraction pattern which is then detected by the photo diode array. If no ferning occurs, the corresponding diffraction pattern will be structureless. The microprocessor is programmed with an algorithm to produce a quantitative index of ferning indicating quantitatively the ferning level. Preferably, a plurality of spots on the sample are measured to determine the ferning level at each spot, and the microprocessor then makes a final determination as to final ferning level on the basis of the test results of all of the spots. This significantly increases the reliability of the final test result, since a defect at one test spot or anomaly of one test result will not be fatal to the final result.

4134853, Jan 16, 1979

Dec 30, 1976

5/755740

Robert Ehrlich - Roslyn Estates NY
Melvin Ehrlich - Roslyn Estates NY

G03C 100
A63H 900

252300

A photochromic composition consisting essentially of titanium dioxide, ferric oxide and lead nitrate. This photochromic compositon can be combined with moldable materials such as a plastisol and formed into toys, such as dolls.