Michael W Senko, 56994 La Mesa Ter UNIT B, Sunnyvale, CA 94086

6573495, Jun 3, 2003

Dec 26, 2000

09/750503

Michael Senko - Sunnyvale CA

Thermo Finnigan LLC - San Jose CA

H01J 4938

250290, 250291, 250292, 250423 R

An ion cyclotron resonance cell having a large ion trapping volume is described. The cell includes elongated spaced concentric electrodes having a common axis in which the trapping volume is the space between the electrodes. The cell may also include trapping electrodes disposed at the ends of the elongated concentric electrodes.

6608303, Aug 19, 2003

Jun 6, 2001

09/875714

Jonathan W. Amy - West Lafayette IN
Michael Senko - Sunnyvale CA
Dennis M. Taylor - San Jose CA

Thermo Finnigan LLC - San Jose CA

B01D 5944

250292

There is provided a quadrupole ion trap mass spectrometer of the type having a plurality of ring electrodes and defining a trapping volume. The quadrupole potential faults arising from apertures in the electrodes are corrected by an apertured shim electrode placed within and spaced from the walls of the electrode apertures.

6797950, Sep 28, 2004

Feb 3, 2003

10/357712

Jae C. Schwartz - San Jose CA
Michael W. Senko - Sunnyvale CA

Thermo Finnegan LLC - San Jose CA

H01J 4942

250292

A three section linear or two-dimensional (2D) quadrupole ion trap as a high performance mass spectrometer is described. Mass analysis is performed by ejecting ions radically out a slot formed in one of the rods using the mass selective instability mode of operation. The slot geometry is optimized to yield high ejection efficiencies. Resolution can be controlled by using appropriate end section potentials to control the axial spread of the ion cloud. Multiple detectors can be used for enhancing sensitivity and for enabling enhanced ion analysis techniques in the ion trap.

6872938, Mar 29, 2005

Mar 20, 2002

10/472917

Alexander Makarov - Cheshire, GB
Mark E. Hardman - Manchester, GB
Jae C. Schwartz - San Jose CA, US
Michael W. Senko - Sunnyvale CA, US

Thermo Finnigan LLC - San Jose CA

B01D059/44

250281, 250292, 250287, 250288

A mass spectrometer comprises an ion source which generates nebulized ions which enter an ion cooler via an ion source block Ions within a window of m/z of interest are extracted via a quadrupole mass filter and passed to a linear trap Ions are trapped in a potential well in the linear trap and are bunched at the bottom of the potential well adjacent an exit segment Ions are gated out of the linear trap into an electrostatic ion trap and are detected by a secondary electron multiplier By bunching the ions in the linear trap prior to ejection, and by focussing the ions in time of flight (TOF) upon the entrance of the electrostatic trap the ions arrive at the electrostatic trap as a convolution of short, energetic packets of similar m/z. Such packets are particularly suited to an electrostatic trap because the FWHM of each packet's TOF distribution is less than the period of oscillation of those ions in the electrostatic trap.

6884996, Apr 26, 2005

Feb 2, 2004

10/771073

Michael W. Senko - Sunnyvale CA, US

Thermo Finnigan LLC - San Jose CA

H01J049/42

250282, 250292, 250283, 250290

Methods, systems and apparatus, including computer program products, for operating a quadrupole ion trap in mass spectrometry. A calibrated resonant frequency is determined precursor ions in a first ion population in an ion trap. A frequency adjustment is determined for the precursor ions in a second ion population based on the number of ions in the second ion population. The ion trap is operated using an adjusted resonant frequency that is based on the calibrated resonant frequency and the determined frequency adjustment.

6911651, Jun 28, 2005

May 8, 2002

10/477022

Michael W. Senko - Sunnyvale CA, US
Jae C. Schwartz - San Jose CA, US

Thermo Finnigan LLC - San Jose CA

H01J049/42

250292, 250282, 250281, 250290

There is provided a quadruple ion trap () of the type including a ring electrode () and first and second end cap electrodes (), which define a trapping volume. The end cap electrodes () include central apertures () for the injection of ions or electrons into the trapping volume and for the ejection of stored ions during the analysis of a sample. Field faults in the RF trapping field are compensated by addition of a concentric recess or depression in the surface of at least one end cap () around the aperture (). There is also provided an ion trap mass spectrometer employing the ion trap.

6936815, Aug 30, 2005

Jun 5, 2003

10/456894

Berg A. Tehlirian - Daly City CA, US
Michael W. Senko - Sunnyvale CA, US
Nigel P. Gore - San Jose CA, US

Thermo Finnigan LLC - San Jose CA

H01J049/00
B01D059/44

250292, 250290

Multipole rod assemblies for guiding or trapping ions in a mass spectrometer. A multipole rod assembly includes a plurality of modules. Each module includes a shield element, one or more insulating elements coupled to the shield element, and one or more multipole rods mounted on the insulating elements, wherein the modules are coupled together to form the multipole rod assembly such that the multipole rods of the modules define an interior volume for guiding or trapping ions.

6995364, Feb 7, 2006

Mar 24, 2005

11/089991

Alexander Makarov - Cheshire, GB
Mark E Hardman - Manchester, GB
Jae C. Schwartz - San Jose CA, US
Michael W. Senko - Sunnyvale CA, US

Thermo Finnigan LLC - San Jose CA

B01D 59/44
H01J 49/00

250290, 250281, 250282, 250292

A mass spectrometer comprises an ion source which generates nebulized ions which enter an ion cooler via an ion source block. Ions within a window of m/z of interest are extracted via a quadrupole mass filter and passed to a linear trap. Ions are trapped in a potential well in the linear trap and are bunched at the bottom of the potential well adjacent an exit segment. Ions are gated out of the linear trap into an electrostatic ion trap and are detected by a secondary electron multiplier. By bunching the ions in the linear trap prior to ejection, and by focussing the ions in time of flight (TOF) upon the entrance of the electrostatic trap , the ions arrive at the electrostatic trap as a convolution of short, energetic packets of similar m/z. Such packets are particularly suited to an electrostatic trap because the FWHM of each packet's TOF distribution is less than the period of oscillation of those ions in the electrostatic trap.