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Monica A Goldberg Deceased1880 Strasburg Rd, Romansville, PA 19320

Related to:
Yetta Goldberg Sylvia Goldberg 63

Monica Goldberg Phones & Addresses

1880 Strasburg Rd, Coatesville, PA 19320    610-4860503    610-4860506   

3 Stanford Rd, Somers Point, NJ 08244    610-4860506   

Philadelphia, PA   

Chester, PA   

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Us Patents

Humanized Anti-Cd134 (Ox40) Antibodies And Uses Thereof

US Patent:
2017036, Dec 28, 2017
Filed:
Sep 11, 2017
Appl. No.:
15/700986
Inventors:
- GJ Almere, NL
- Titusville NJ, US
Jinquan LUO - Spring House PA, US
Randall BREZSKI - Spring House PA, US
Monica GOLDBERG - Spring House PA, US
International Classification:
C07K 16/30
C07K 16/28
Abstract:
The invention provides antibodies that specifically bind to human CD134. Anti-human CD134 antibodies specifically bind to the extracellular domain of human CD134, including non-OX40 ligand (OX40L) binding domains on human CD134, which is expressed on e.g. activated human conventional effector CD4 and/or CD8 T lymphocytes (Teffs) and on activated human suppressive regulatory CD4 T lymphocytes (Tregs). Humanized anti-human CD134 antibodies are useful (e.g. to empower Teffs anti-cancer effector function and/or to inhibit Tregs suppressive function) for cancer treatment.

Humanized Anti-Cd134 (Ox40) Antibodies And Uses Thereof

US Patent:
2014037, Dec 25, 2014
Filed:
Mar 20, 2014
Appl. No.:
14/221212
Inventors:
- Titusville NJ, US
- Utrecht, NL
Jinquan LUO - Spring House PA, US
Randall BREZSKI - Spring House PA, US
Monica GOLDBERG - Spring House PA, US
Assignee:
JANSSEN PHARMACEUTICALS, INC. - Titusville NJ
BIOCEROX PRODUCTS B.V. - Utrecht
International Classification:
C07K 16/30
US Classification:
4241741, 5303897, 536 2353, 4353201, 5303873, 435334
Abstract:
The invention provides antibodies that specifically bind to human CD134. Anti-human CD134 antibodies specifically bind to the extracellular domain of human CD134, including non-OX40 ligand (OX40L) binding domains on human CD134, which is expressed on e.g. activated human conventional effector CD4 and/or CD8 T lymphocytes (Teffs) and on activated human suppressive regulatory CD4 T lymphocytes (Tregs). Humanized anti-human CD134 antibodies are useful (e.g. to empower Teffs anti-cancer effector function and/or to inhibit Tregs suppressive function) for cancer treatment.

Possible Relatives

David R Goldberg  Dean G Goldberg  Deanna Goldberg  Dale Goldberg  Deborah R Goldberg  Daniel Goldberg  Deidre E Goldberg  Monica A Johnson  Monica J Johnston  Monica L White 

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